Search Results - "Karkala Sreedhara Ranganath Pai"
-
1
Oxidative stress and female reproductive disorder: A review
Published in Asian pacific journal of reproduction (01-05-2022)“…Oxidative stress arises from an imbalance between the body’s pro-oxidants and antioxidants. Recently, oxidative stress has been proven a contributing factor to…”
Get full text
Journal Article -
2
Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?
Published in Environmental science and pollution research international (01-12-2021)“…The pool of primordial follicles formed in the ovaries during early development determines the span and quality of fertility in the reproductive life of a…”
Get full text
Journal Article -
3
Beneficial Effect of Cissus quadrangularis Linn. on Osteopenia Associated with Streptozotocin-Induced Type 1 Diabetes Mellitus in Male Wistar Rats
Published in Advances in Pharmacological Sciences (01-01-2014)“…Petroleum ether fraction of Cissus quadrangularis (PECQ) impact on the development of osteopenia in type 1 diabetic rat model has been evaluated. Diabetic rats…”
Get full text
Journal Article -
4
Computational drug repurposing of Akt-1 allosteric inhibitors for non-small cell lung cancer
Published in Scientific reports (16-05-2023)“…Non-small cell lung carcinomas (NSCLC) are the predominant form of lung malignancy and the reason for the highest number of cancer-related deaths. Widespread…”
Get full text
Journal Article -
5
Docking Studies and Biological Activity of Fosinopril Analogs
Published in International Journal of Medicinal Chemistry (Online) (01-01-2014)“…The purpose of the present study was to determine the angiotensin-I converting enzyme inhibitory activity of few novel Fosinopril derivatives which were…”
Get full text
Journal Article -
6
Influence of Ascorbic Acid on Di-(2-Ethylhexyl) Phthalate-induced Ovarian Gene Alterations in Pubertal Female Wistar Rats
Published in Journal of pharmacology & pharmacotherapeutics (01-06-2024)“…Background Di-(2-ethylhexyl) phthalate (DEHP), a plasticizer compound affecting female reproduction, leads to scenarios, such as polycystic ovarian syndrome…”
Get full text
Journal Article -
7
Retracted: Bisindole‐oxadiazole hybrids, T3P mediated® ‐synthesis and appraisal of their apoptotic, antimetastatic and computational Bcl‐2 binding potential
Published in Journal of biochemical and molecular toxicology (01-11-2017)“…Retraction: Kamath PR, Joseph MM, Ajees AA, et al. Bisindole‐oxadiazole hybrids, T3P mediated synthesis and appraisal of their apoptotic, antimetastatic and…”
Get full text
Journal Article -
8
Antitumor and antioxidant activity of Polyalthia longifolia stem bark ethanol extract
Published in Pharmaceutical biology (01-06-2010)“…In the present study, the ethanol extract of stem bark of Polyalthia longifolia Benth. and Hook (Annonaceae) was screened for its in vitro and in vivo…”
Get more information
Journal Article -
9
Design, development, drug-likeness, and molecular docking studies of novel piperidin-4-imine derivatives as antitubercular agents
Published in Drug design, development and therapy (01-01-2015)“…Tuberculosis remains one of the major grievous diseases worldwide. The emergence of resistance to antituberculosis drugs emphasize the necessity to discover…”
Get full text
Journal Article -
10
Treatments for psoriasis: A journey from classical to advanced therapies. How far have we reached?
Published in European journal of pharmacology (15-08-2022)Get full text
Journal Article -
11
Chitosan-glucuronic acid conjugate coated mesoporous silica nanoparticles: A smart pH-responsive and receptor-targeted system for colorectal cancer therapy
Published in Carbohydrate polymers (01-06-2021)“…•Capecitabine was loaded in mesoporous silica nanoparticles (MSNs).•Chitosan-glucuronic acid was used for coating of MSNs to ensure targeted drug…”
Get full text
Journal Article -
12
Synthesis, docking and anti-tumor activity of beta-L-1,3-thiazolidine pyrimidine nucleoside analogues
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-09-2007)“…In the search for effective, selective, and nontoxic antiviral and antitumor agents, a variety of strategies have been devised to design nucleoside analogues…”
Get more information
Journal Article -
13
Mesoporous silica nanoparticles capped with chitosan-glucuronic acid conjugate for pH-responsive targeted delivery of 5-fluorouracil
Published in Journal of drug delivery science and technology (01-06-2021)“…In the present work, we designed mesoporous silica nanoparticles (MSNs) capped with chitosan-glucuronic acid (CHS-GCA) conjugate for pH-responsive targeted…”
Get full text
Journal Article -
14
Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts
Published in Journal of pharmacy and pharmacology (01-07-2013)“…Objectives Exposure to toxicants like doxorubicin (Dox) damages cellular components by generating reactive oxygen species (ROS). This can be attenuated using…”
Get full text
Journal Article -
15
Bisindole-oxadiazole hybrids, T3P ® -mediated synthesis, and appraisal of their apoptotic, antimetastatic, and computational Bcl-2 binding potential
Published in Journal of biochemical and molecular toxicology (01-11-2017)“…In the pursuit of novel anticancer leads, new bisindole-oxadiazoles were synthesized using propyl phosphonic anhydride as a mild and efficient reagent. The…”
Get full text
Journal Article -
16
Selective Cytotoxicity and Pro-apoptotic Activity of Stem Bark of Wrightia tinctoria (Roxb.) R. Br. in Cancerous Cells
Published in Pharmacognosy Magazine (01-10-2015)“…Wrightia tinctoria (Roxb.) R. Br. is a widely available shrub in India used traditionally in various ailments, including cancer. However, the anticancer…”
Get full text
Journal Article -
17
Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma
Published in BMC complementary and alternative medicine (10-03-2015)“…Nardostachys jatamansi DC is a Himalayan medicinal herb that has been described in various traditional systems of medicine for its use in cancer. In view of…”
Get full text
Journal Article -
18
Beneficial Effect of Cissus quadrangularis Linn. on Osteopenia Associated with Streptozotocin-Induced Type 1 Diabetes Mellitus in Male Wistar Rats
Published in Advances in pharmacological sciences (2014)“…Petroleum ether fraction of Cissus quadrangularis (PECQ) impact on the development of osteopenia in type 1 diabetic rat model has been evaluated. Diabetic rats…”
Get full text
Journal Article