Search Results - "Karjalainen, Reijo"

Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases by Kaarniranta, Kai, Koskela, Ali, Kårlund, Anna, Reinisalo, Mika, Karjalainen, Reijo O.

“…Numerous studies have highlighted the key roles of oxidative stress and inflammation in aging-related diseases such as obesity, type 2 diabetes, age-related…”
Get full text

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease by Vepsäläinen, Saila, Koivisto, Henna, Pekkarinen, Elina, Mäkinen, Petra, Dobson, Gary, McDougall, Gordon J, Stewart, Derek, Haapasalo, Annakaisa, Karjalainen, Reijo O, Tanila, Heikki, Hiltunen, Mikko

“…A growing body of epidemiological evidence suggests that fruit and vegetable juices containing various phenolic compounds can reduce the risk of Alzheimer's…”
Get full text

Stability of anthocyanins in berry juices stored at different temperatures by Hellström, Jarkko, Mattila, Pirjo, Karjalainen, Reijo

“…•Berry juice anthocyanins degrade significantly during storage.•Storage temperature is the major influence on anthocyanin stability.•Juice matrix has the…”
Get full text

Nontargeted Metabolite Profiles and Sensory Properties of Strawberry Cultivars Grown both Organically and Conventionally by Kårlund, Anna, Hanhineva, Kati, Lehtonen, Marko, Karjalainen, Reijo O, Sandell, Mari

“…Strawberry (Fragaria × ananassa Duch.) contains many secondary metabolites potentially beneficial for human health, and several of these compounds contribute…”
Get full text

High-Performance Liquid Chromatography Analysis of Black Currant (Ribes nigrum L.) Fruit Phenolics Grown either Conventionally or Organically by Anttonen, Mikko J, Karjalainen, Reijo O

“…Black currants (Ribes nigrum L.) contain a diverse range of phenolics and possess a high antioxidant activity, which makes them an interesting target for the…”
Get full text

Polyphenols in Strawberry (Fragaria × ananassa) Leaves Induced by Plant Activators by Kårlund, Anna, Salminen, Juha-Pekka, Koskinen, Piia, Ahern, Jeffrey R, Karonen, Maarit, Tiilikkala, Kari, Karjalainen, Reijo O

“…Strawberry leaves contain high amounts of diverse phenolic compounds potentially possessing defensive activities against microbial pathogens and beneficial…”
Get full text

Non‐targeted metabolite profiling highlights the potential of strawberry leaves as a resource for specific bioactive compounds by Kårlund, Anna, Hanhineva, Kati, Lehtonen, Marko, McDougall, Gordon J, Stewart, Derek, Karjalainen, Reijo O

“…BACKGROUND The non‐edible parts of horticultural crops, such as leaves, contain substantial amounts of valuable bioactive compounds which are currently only…”
Get full text

Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells by Koskela, Ali, Reinisalo, Mika, Hyttinen, Juha M T, Kaarniranta, Kai, Karjalainen, Reijo O

“…In this work, we investigated the ability of pinosylvin (PS), 3,5-dihydroxy-trans-stilbene, to modulate oxidative stress in human RPE cells. PS, a stilbenoid…”
Get full text

Metabolic profiling discriminates between strawberry (Fragaria×ananassa Duch.) cultivars grown in Finland or Estonia by Kårlund, Anna, Moor, Ulvi, McDougall, Gordon, Lehtonen, Marko, Karjalainen, Reijo O., Hanhineva, Kati

“…Metabolic profiling analysis with LC-ESI-QTOF-MS was utilized to separate and identify 186 putative major metabolites demonstrating significantly different…”
Get full text

Effects of Juice Matrix and Pasteurization on Stability of Black Currant Anthocyanins during Storage by Dobson, Gary, McDougall, Gordon J., Stewart, Derek, Cubero, Miguel Ángel, Karjalainen, Reijo O.

“…The effects of juice matrix and pasteurization on the stability of total phenols and especially total and individual anthocyanins were examined in black…”
Get full text

Influence of Fertilization, Mulch Color, Early Forcing, Fruit Order, Planting Date, Shading, Growing Environment, and Genotype on the Contents of Selected Phenolics in Strawberry (Fragaria × ananassa Duch.) Fruits by Anttonen, Mikko J, Hoppula, Kalle I, Nestby, Rolf, Verheul, Michél J, Karjalainen, Reijo O

“…The influence of agricultural practices (fertilization, mulch color, early forcing, and planting date), environment (light and growing area), cultivar, and…”
Get full text

Environmental and genetic variation of phenolic compounds in red raspberry by Anttonen, Mikko J., Karjalainen, Reijo O.

“…Red raspberry ( Rubus idaeus L.) is an economically important berry crop that contains numerous phenolic compounds with potential health benefits. It is known…”
Get full text

Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells by Koskela, Ali, Reinisalo, Mika, Petrovski, Goran, Sinha, Debasish, Olmiere, Céline, Karjalainen, Reijo, Kaarniranta, Kai

“…Impaired autophagic and proteasomal cleansing have been documented in aged retinal pigment epithelial (RPE) cells and age-related macular degeneration (AMD)…”
Get full text

Benzothiadiazole Induces the Accumulation of Phenolics and Improves Resistance to Powdery Mildew in Strawberries by Hukkanen, Anne T, Kokko, Harri I, Buchala, Antony J, McDougall, Gordon J, Stewart, Derek, Kärenlampi, Sirpa O, Karjalainen, Reijo O

“…Benzothiadiazole (BTH) enhanced the accumulation of soluble and cell-wall-bound phenolics in strawberry leaves and also improved the resistance to powdery…”
Get full text

Leaf phenolic compounds in red clover ( Trifolium pratense L.) induced by exposure to moderately elevated ozone by Saviranta, Niina M.M., Julkunen-Tiitto, Riitta, Oksanen, Elina, Karjalainen, Reijo O.

“…Red clover ( Trifolium pratense L.), an important feed crop in many parts of the world, is exposed to elevated ozone over large areas. Plants can limit…”
Get full text

Plant flavonol quercetin and isoflavone biochanin A differentially induce protection against oxidative stress and inflammation in ARPE-19 cells by Saviranta, Niina M.M., Veeroos, Laura, Granlund, Lars J., Hassinen, Viivi H., Kaarniranta, Kai, Karjalainen, Reijo O.

“…In this work, differential ability of plant flavonol quercetin and plant isoflavone biochanin A to modulate oxidative stress and inhibit inflammation-related…”
Get full text

Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells by Paimela, Tuomas, Hyttinen, Juha M.T., Viiri, Johanna, Ryhänen, Tuomas, Karjalainen, Reijo O., Salminen, Antero, Kaarniranta, Kai

“…Elevated nuclear factor kappa B (NF-κB) activity and interleukin-6 (IL-6) secretion participates in the pathology of several age and inflammatory-related…”
Get full text

Red clover (Trifolium pratense L.) isoflavones: determination of concentrations by plant stage, flower colour, plant part and cultivar by Saviranta, Niina MM, Anttonen, Mikko J, von Wright, Atte, Karjalainen, Reijo O

“…BACKGROUND: Red clover (Trifolium pratense L.), a widely used fodder, has recently received considerable interest as a valuable source of isoflavones for many…”
Get full text

Fortification of blackcurrant juice with crowberry: Impact on polyphenol composition, urinary phenolic metabolites, and postprandial glycemic response in healthy subjects by Törrönen, Riitta, McDougall, Gordon J., Dobson, Gary, Stewart, Derek, Hellström, Jarkko, Mattila, Pirjo, Pihlava, Juha-Matti, Koskela, Ali, Karjalainen, Reijo

“…Functional drinks enhanced with putatively bioactive polyphenols are receiving extensive interest due to their potential health benefits. A randomized,…”
Get full text

Metabolite profiling of leek (Allium porrum L) cultivars by (1) H NMR and HPLC-MS by Soininen, Tuula H, Jukarainen, Niko, Soininen, Pasi, Auriola, Seppo O K, Julkunen-Tiitto, Riitta, Oleszek, Wieslaw, Stochmal, Anna, Karjalainen, Reijo O, Vepsäläinen, Jouko J

“…Leek (Allium ampeloprasum var. porrum) is consumed as a vegetable throughout the world. However, little is known about the metabolites of leek cultivars,…”
Get full text