Search Results - "Kariya, Yukiko"

αvβ3 Integrin induces partial EMT independent of TGF-β signaling by Kariya, Yoshinobu, Oyama, Midori, Suzuki, Takato, Kariya, Yukiko

“…Epithelial–mesenchymal transition (EMT) plays a pivotal role for tumor progression. Recent studies have revealed the existence of distinct intermediate states…”
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β4-Integrin/PI3K Signaling Promotes Tumor Progression through the Galectin-3- N -Glycan Complex by Kariya, Yukiko, Oyama, Midori, Hashimoto, Yasuhiro, Gu, Jianguo, Kariya, Yoshinobu

“…Malignant transformation is associated with aberrant -glycosylation, but the role of protein -glycosylation in cancer progression remains poorly defined…”
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Integrin α6β4 Confers Doxorubicin Resistance in Cancer Cells by Suppressing Caspase-3-Mediated Apoptosis: Involvement of N-Glycans on β4 Integrin Subunit by Kariya, Yoshinobu, Gu, Jianguo, Kariya, Yukiko

“…Drug resistance is a major obstacle to successful cancer treatment. Therefore, it is essential to understand the molecular mechanisms underlying drug…”
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Osteopontin in Cancer: Mechanisms and Therapeutic Targets by Kariya, Yoshinobu, Kariya, Yukiko

“…Despite significant advances in the understanding of cancer biology, cancer is still a leading cause of death worldwide. Expression of the tumor…”
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Roles of Integrin α6β4 Glycosylation in Cancer by Kariya, Yoshinobu, Kariya, Yukiko, Gu, Jianguo

“…Malignant transformation is accompanied with aberrant glycosylation of proteins. Such changes in glycan structure also occur in the integrins, which are a…”
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Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility by Kariya, Yoshinobu, Oyama, Midori, Kariya, Yukiko, Hashimoto, Yasuhiro

“…Osteopontin (OPN) plays a pivotal role in cancer cell invasion and metastasis. Although OPN has a large number of phosphorylation sites, the functional…”
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RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells by Kariya, Yukiko, Tatsuta, Takeo, Sugawara, Shigeki, Kariya, Yoshinobu, Nitta, Kazuo, Hosono, Masahiro

“…Sialic acid-binding lectin obtained from bullfrog eggs (SBL) induces cell death in cancer cells but not in normal cells. This antitumor effect is mediated…”
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Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration by Kariya, Yoshinobu, Sato, Hiroki, Katou, Naoko, Kariya, Yukiko, Miyazaki, Kaoru

“…Laminin-332 (α3ß3γ2) (Lm332) supports the stable anchoring of basal keratinocytes to the epidermal basement membrane, while it functions as a motility factor…”
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Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells by Tatsuta, Takeo, Hosono, Masahiro, Sugawara, Shigeki, Kariya, Yukiko, Ogawa, Yukiko, Hakomori, Senitiroh, Nitta, Kazuo

“…Sialic acid binding lectin (SBL) isolated from Rana catesbeiana oocytes is a multifunctional protein which has lectin activity, ribonuclease activity and…”
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Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs by TATSUTA, TAKEO, HOSONO, MASAHIRO, MIURA, YUKI, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO

“…Sialic-acid binding lectin (SBL) isolated from bullfrog (Rana catesbeiana) oocytes is a multifunctional protein which has lectin activity, ribonuclease…”
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Increased cerebrospinal fluid osteopontin levels and its involvement in macrophage infiltration in neuromyelitis optica by Kariya, Yoshinobu, Kariya, Yukiko, Saito, Toshie, Nishiyama, Shuhei, Honda, Takashi, Tanaka, Keiko, Yoshida, Mari, Fujihara, Kazuo, Hashimoto, Yasuhiro

“…Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system that predominantly affects the optic nerves and spinal cord. Although NMO…”
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Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL by TATSUTA, TAKEO, HOSONO, MASAHIRO, TAKAHASHI, KOHTA, OMOTO, TAKASHI, KARIYA, YUKIKO, SUGAWARA, SHIGEKI, HAKOMORI, SENITIROH, NITTA, KAZUO

“…Malignant mesothelioma is a highly aggressive tumor with poor prognosis. An effective drug for treatment of malignant mesothelioma is greatly needed. Sialic…”
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