Search Results - "Kariya, Ryusho"

Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models by Okada, Seiji, Vaeteewoottacharn, Kulthida, Kariya, Ryusho

“…Patient-derived xenograft (PDX) models are created by engraftment of patient tumor tissues into immunocompetent mice. Since a PDX model retains the…”
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Establishment of a Patient-Derived Tumor Xenograft Model and Application for Precision Cancer Medicine by Okada, Seiji, Vaeteewoottacharn, Kulthida, Kariya, Ryusho

“…Patient-derived xenograft (PDX) models can be created with the transplantation of cancerous cells or tissues from patients’ primary tumors into immunodeficient…”
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Efficacy and mechanism of the anti-CD38 monoclonal antibody Daratumumab against primary effusion lymphoma by Panaampon, Jutatip, Kariya, Ryusho, Okada, Seiji

“…Primary effusion lymphoma (PEL) is a rare, aggressive B cell non-Hodgkin’s lymphoma of the body cavities with malignant effusions. The prognosis is poor, and…”
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Elotuzumab, a potential therapeutic humanized anti-SLAMF7 monoclonal antibody, enhances natural killer cell-mediated killing of primary effusion lymphoma cells by Panaampon, Jutatip, Kariya, Ryusho, Okada, Seiji

“…Primary effusion lymphoma (PEL) is a rare aggressive B-cell non-Hodgkin’s lymphoma with no optimal treatment. Signaling lymphocytic activation molecule-F7…”
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PAX5 functions as a tumor suppressor by RB-E2F-mediated cell cycle arrest in Kaposi sarcoma-associated herpesvirus-infected primary effusion lymphoma by Goto, Hiroki, Kariya, Ryusho, Kudo, Eriko, Katano, Harutaka, Okada, Seiji

“…•PAX5 is silenced in KSHV-infected PEL cells via its promoter methylation.•PAX5 induced G1 cell cycle arrest via reduction of RB-E2F-regulated genes.•PAX5…”
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Cucurbitacin B induces apoptosis of primary effusion lymphoma via disruption of cytoskeletal organization by Ueno, Mikinori, Kariya, Ryusho, Sittithumcharee, Gunya, Okada, Seiji

“…•CuB inhibited cell proliferation of PEL•CuB caused apoptosis of BCBL-1 cells via caspase activation•CuB interacted with actin and decreased G-actin protein…”
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Evaluating the Use of Sacran, a Polysaccharide Isolated from Aphanothece sacrum , as a Possible Microbicide for Preventing HIV-1 Infection by Matsuda, Kouki, Kariya, Ryusho, Maeda, Kenji, Okada, Seiji

“…Since combination antiretroviral therapy (cART) was introduced to treat human immunodeficiency virus type-1 (HIV-1)/acquired immunodeficiency syndrome (AIDS),…”
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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination by Yasuda, Tadahito, Koiwa, Mayu, Yonemura, Atsuko, Miyake, Keisuke, Kariya, Ryusho, Kubota, Sho, Yokomizo-Nakano, Takako, Yasuda-Yoshihara, Noriko, Uchihara, Tomoyuki, Itoyama, Rumi, Bu, Luke, Fu, Lingfeng, Arima, Kota, Izumi, Daisuke, Iwagami, Shiro, Eto, Kojiro, Iwatsuki, Masaaki, Baba, Yoshifumi, Yoshida, Naoya, Ohguchi, Hiroto, Okada, Seiji, Matsusaki, Keisuke, Sashida, Goro, Takahashi, Akiko, Tan, Patrick, Baba, Hideo, Ishimoto, Takatsugu

“…In the tumor microenvironment, senescent non-malignant cells, including cancer-associated fibroblasts (CAFs), exhibit a secretory profile under stress…”
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Anti-human CD99 antibody exerts potent antitumor effects in mantle cell lymphoma by Takheaw, Nuchjira, Sittithumcharee, Gunya, Kariya, Ryusho, Kasinrerk, Watchara, Okada, Seiji

“…CD99 is a surface molecule expressed on various cell types including cancer cells. Expression of CD99 on multiple myeloma is associated with CCND1-IGH fusion/…”
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Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma by Boonnate, Piyanard, Kariya, Ryusho, Okada, Seiji

“…Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers. ATLL has…”
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Attenuation of CD47-SIRPα Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis by Vaeteewoottacharn, Kulthida, Kariya, Ryusho, Pothipan, Phattarin, Fujikawa, Sawako, Pairojkul, Chawalit, Waraasawapati, Sakda, Kuwahara, Kazuhiko, Wongkham, Chaisiri, Wongkham, Sopit, Okada, Seiji

“…The involvement of chronic inflammation in cholangiocarcinoma (CCA) progression is well established. Cluster of differentiation 47 (CD47) is mutually expressed…”
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Homophilic Interaction of CD147 Promotes IL-6-Mediated Cholangiocarcinoma Invasion via the NF-κB-Dependent Pathway by Dana, Paweena, Kariya, Ryusho, Lert-Itthiporn, Worachart, Seubwai, Wunchana, Saisomboon, Saowaluk, Wongkham, Chaisiri, Okada, Seiji, Wongkham, Sopit, Vaeteewoottacharn, Kulthida

“…Cholangiocarcinoma (CCA), an aggressive cancer of bile ducts, is a well-known chronic inflammation-related disease. The major impediment in CCA treatment is…”
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Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells by Saisomboon, Saowaluk, Kariya, Ryusho, Mahalapbutr, Panupong, Insawang, Tonkla, Sawanyawisuth, Kanlayanee, Cha'on, Ubon, Rungrotmongkol, Thanyada, Wongkham, Sopit, Jitrapakdee, Sarawut, Okada, Seiji, Vaeteewoottacharn, Kulthida

“…We have previously shown that the overexpression of acetyl-CoA carboxylase 1 (ACC1) was associated with the poor prognosis of cholangiocarcinoma (CCA)…”
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Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress by Masud Alam, Md, Kariya, Ryusho, Kawaguchi, Azusa, Matsuda, Kouki, Kudo, Eriko, Okada, Seiji

“…Autophagy plays a crucial role in cancer cell survival and the inhibition of autophagy is attracting attention as an emerging strategy for the treatment of…”
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Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF‐κB pathway by Goto, Hiroki, Kariya, Ryusho, Shimamoto, Masako, Kudo, Eriko, Taura, Manabu, Katano, Harutaka, Okada, Seiji

“…Primary effusion lymphoma (PEL) is an infrequent and distinct entity among the aggressive non‐Hodgkin B cell lymphomas that occurs predominantly in patients…”
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A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts by Wei, Feng, Uchihara, Tomoyuki, Yonemura, Atsuko, Yasuda‐Yoshihara, Noriko, Yasuda, Tadahito, Semba, Takashi, Fukuda, Masahiro, Akiyama, Takahiko, Kitamura, Fumimasa, Bu, Luke, Hu, Xichen, Fu, Lingfeng, Zhang, Jun, Kariya, Ryusho, Yamasaki, Juntaro, Aihara, Kazuki, Yamashita, Kohei, Nagano, Osamu, Okada, Seiji, Baba, Hideo, Ishimoto, Takatsugu

“…Fibroblast activation protein (FAP) generally shows low or undetectable expression in most normal tissues but is highly expressed in fibroblasts in almost all…”
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Cepharanthine inhibited HIV-1 cell–cell transmission and cell-free infection via modification of cell membrane fluidity by Matsuda, Kouki, Hattori, Shinichiro, Komizu, Yuji, Kariya, Ryusho, Ueoka, Ryuichi, Okada, Seiji

“…The anti-HIV-1 activity of cepharanthine (CEP), a natural product derived from Stephania cepharantha Hayata, was evaluated. CEP stabilized plasma membrane…”
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Inhibition of HIV-1 entry by the tricyclic coumarin GUT-70 through the modification of membrane fluidity by Matsuda, Kouki, Hattori, Shinichiro, Kariya, Ryusho, Komizu, Yuji, Kudo, Eriko, Goto, Hiroki, Taura, Manabu, Ueoka, Ryuichi, Kimura, Shinya, Okada, Seiji

“…Membrane fusion between host cells and HIV-1 is the initial step in HIV-1 infection, and plasma membrane fluidity strongly influences infectivity. In the…”
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Terminal fucose mediates progression of human cholangiocarcinoma through EGF/EGFR activation and the Akt/Erk signaling pathway by Indramanee, Somsiri, Sawanyawisuth, Kanlayanee, Silsirivanit, Atit, Dana, Paweena, Phoomak, Chatchai, Kariya, Ryusho, Klinhom-on, Nathakan, Sorin, Supannika, Wongkham, Chaisiri, Okada, Seiji, Wongkham, Sopit

“…Aberrant glycosylation is recognized as a cancer hallmark that is associated with cancer development and progression. In this study, the clinical relevance and…”
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Induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic apoptotic pathways in primary effusion lymphoma by Alam, Md Masud, Kariya, Ryusho, Boonnate, Piyanard, Kawaguchi, Azusa, Okada, Seiji

“…•Shikonin (SHK) induced apoptosis in Primary effusion lymphoma (PEL).•SHK treatment rabidly generated ROS and activated JNK and p38.•SHK inhibited ascites…”
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