Search Results - "Kariya, Ken‐ichi"

Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development by Kawabe, Hiroshi, Neeb, Antje, Dimova, Kalina, Young, Samuel M., Takeda, Michiko, Katsurabayashi, Shutaro, Mitkovski, Miso, Malakhova, Oxana A., Zhang, Dong-Er, Umikawa, Masato, Kariya, Ken-ichi, Goebbels, Sandra, Nave, Klaus-Armin, Rosenmund, Christian, Jahn, Olaf, Rhee, JeongSeop, Brose, Nils

“…Nedd4-1 is a “ neuronal precursor cell expressed and developmentally downregulated protein” and among the most abundant E3 ubiquitin ligases in mammalian…”
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MicroRNA-196a-5p is a potential prognostic marker of delayed lymph node metastasis in early-stage tongue squamous cell carcinoma by Maruyama, Tessho, Nishihara, Kazuhide, Umikawa, Masato, Arasaki, Akira, Nakasone, Toshiyuki, Nimura, Fumikazu, Matayoshi, Akira, Takei, Kimiko, Nakachi, Saori, Kariya, Ken-Ichi, Yoshimi, Naoki

“…MicroRNAs (miRs) are expected to serve as prognostic tools for cancer. However, many miRs have been reported as prognostic markers of recurrence or metastasis…”
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Smad inhibition by the Ste20 kinase Misshapen by Kaneko, Satoshi, Chen, Xiaochu, Lu, Peiyuan, Yao, Xiaohao, Wright, Theodore G, Rajurkar, Mihir, Kariya, Ken-ichi, Mao, Junhao, Ip, Y. Tony, Xu, Lan

“…The level of TGF-β/bone morphogenetic protein (BMP) signaling through Smad is tightly regulated to ensure proper embryonic patterning and homeostasis. Here we…”
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The Traf2- and Nck-interacting Kinase as a Putative Effector of Rap2 to Regulate Actin Cytoskeleton by Taira, Kiyohito, Umikawa, Masato, Takei, Kimiko, Myagmar, Bat-Erdene, Shinzato, Manabu, Machida, Noriko, Uezato, Hiroshi, Nonaka, Shigeo, Kariya, Ken-ichi

“…Rap2 belongs to the Ras family of small GTP-binding proteins, but its specific roles in cell signaling remain unknown. In the present study, we have…”
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Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 as a Putative Effector of Rap2 to Activate the c-Jun N-terminal Kinase by Machida, Noriko, Umikawa, Masato, Takei, Kimiko, Sakima, Nariko, Myagmar, Bat-Erdene, Taira, Kiyohito, Uezato, Hiroshi, Ogawa, Yoshihide, Kariya, Ken-ichi

“…Little is known about the specific signaling roles of Rap2, a Ras family small GTP-binding protein. In a search for novel Rap2-interacting proteins by the…”
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MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1 by Nonaka, Hideo, Takei, Kimiko, Umikawa, Masato, Oshiro, Minoru, Kuninaka, Kouichi, Bayarjargal, Maitsetseg, Asato, Tsuyoshi, Yamashiro, Yoshito, Uechi, Yukiko, Endo, Shogo, Suzuki, Tatsuo, Kariya, Ken-ichi

“…Rap1 and Rap2 are similar Ras-like G proteins but perform distinct functions. By the affinity chromatography/mass-spectrometry approach and the yeast…”
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A genotype distribution of human papillomaviruses detected by polymerase chain reaction and direct sequencing analysis in a large sample of common warts in Japan by Hagiwara, Keisuke, Uezato, Hiroshi, Arakaki, Hajime, Nonaka, Shigeo, Nonaka, Kimiko, Nonaka, Hideo, Asato, Tsuyoshi, Oshiro, Minoru, Kariya, Ken-ichi, Hattori, Akira

“…There have been no large‐scale epidemiological studies of human papillomavirus (HPV) genotype distribution of common warts in Japan. A total of 213 patients…”
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Identification and Characterization of RA-GEF-2, a Rap Guanine Nucleotide Exchange Factor That Serves as a Downstream Target of M-Ras by Gao, Xianlong, Satoh, Takaya, Liao, Yanhong, Song, Chunhua, Hu, Chang-Deng, Kariya, Ken-ichi, Kataoka, Tohru

“…The Ras family small GTPase Rap is regulated by an array of specific guanine nucleotide exchange factors (GEFs) in response to upstream stimuli. RA-GEF-1 was…”
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Persistence of human papillomavirus infection as a predictor for recurrence in carcinoma of the cervix after radiotherapy by Nagai, Yutaka, Toma, Takashi, Moromizato, Hidehiko, Maehama, Toshiyuki, Asato, Tsuyoshi, Kariya, Ken-ichi, Kanazawa, Koji

“…This study was undertaken to examine a possible correlation between clearance or persistence of human papillomavirus (HPV) infection and radiation response in…”
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PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector by Myagmar, Bat-Erdene, Umikawa, Masato, Asato, Tsuyoshi, Taira, Kiyohito, Oshiro, Minoru, Hino, Asako, Takei, Kimiko, Uezato, Hiroshi, Kariya, Ken-ichi

“…Rap2 belongs to the Ras family of small GTP-binding proteins, but its specific signaling role is unclear. By yeast two-hybrid screening, we have found that the…”
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Proteomic analysis of the trabecular meshwork of rats in a steroid-induced ocular hypertension model: downregulation of type I collagen C-propeptides by Shinzato, Manabu, Yamashiro, Yoshito, Miyara, Nariko, Iwamatsu, Akihiro, Takeuchi, Kouji, Umikawa, Masato, Bayarjargal, Maitsetseg, Kariya, Ken-ichi, Sawaguchi, Shoichi

“…To investigate global protein expression profiles in the trabecular meshwork (TM) of normal and glucocorticoid-induced ocular hypertensive rat eyes by…”
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RA-GEF, a Novel Rap1A Guanine Nucleotide Exchange Factor Containing a Ras/Rap1A-associating Domain, Is Conserved between Nematode and Humans by Liao, Y, Kariya, K, Hu, C D, Shibatohge, M, Goshima, M, Okada, T, Watari, Y, Gao, X, Jin, T G, Yamawaki-Kataoka, Y, Kataoka, T

“…A yeast two-hybrid screening for Ras-binding proteins in nematode Caenorhabditis elegans has identified a guanine nucleotide exchange factor (GEF) containing a…”
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The Strength of Interaction at the Raf Cysteine-Rich Domain Is a Critical Determinant of Response of Raf to Ras Family Small GTPases by Okada, T, Hu, C D, Jin, T G, Kariya, K, Yamawaki-Kataoka, Y, Kataoka, T

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Cysteine-rich Region of Raf-1 Interacts with Activator Domain of Post-translationally Modified Ha-Ras (∗) by Hu, Chang-Deng, Kariya, Ken-ichi, Tamada, Masako, Akasaka, Kazuhito, Shirouzu, Mikako, Yokoyama, Shigeyuki, Kataoka, Tohru

“…The interaction between “switch I/effector domain” of Ha-Ras and the Ras-binding domain (RBD, amino acid 51-131) of Raf-1 is essential for signal transduction…”
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Association of Yeast Adenylyl Cyclase with Cyclase-Associated Protein CAP Forms a Second Ras-Binding Site Which Mediates Its Ras-Dependent Activation by Shima, Fumi, Okada, Tomoyo, Kido, Masahiro, Sen, Hiroyoshi, Tanaka, Yasuhiro, Tamada, Masako, Hu, Chang-Deng, Yamawaki-Kataoka, Yuriko, Kariya, Ken-ichi, Kataoka, Tohru

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization of a Novel Ras-Binding Protein Ce-FLI-1 Comprising Leucine-Rich Repeats and Gelsolin-like Domains by Goshima, Masahiro, Kariya, Ken-ichi, Yamawaki-Kataoka, Yuriko, Okada, Tomoyo, Shibatohge, Mitsushige, Shima, Fumi, Fujimoto, Etsuko, Kataoka, Tohru

“…Ras proteins are conserved from yeasts to mammals and implicated in regulation of the actin cytoskeleton. Theflightless-1(fli-1) gene ofDrosophila…”
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Effect of Phosphorylation on Activities of Rap1A to Interact with Raf-1 and to Suppress Ras-dependent Raf-1 Activation by Hu, Chang-Deng, Kariya, Ken-ichi, Okada, Tomoyo, Qi, Xiaodong, Song, Chunhua, Kataoka, Tohru

“…Rap1A is phosphorylated by cAMP-dependent protein kinase (PKA), and this phosphorylation has been shown to modulate its interaction with other proteins…”
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A Case of Bullous Congenital Ichthyosiform Erythroderma (BCIE) Caused by a Mutation in the 1A Helix Initiation Motif of Keratin 1 by Uezato, Hiroshi, Yamamoto, Yu‐ichi, Kuwae, Chojiro, Nonaka, Kimiko, Oshiro, Minoru, Kariya, Ken‐ichi, Nonaka, Shigeo

“…Bullous congenital ichthyosiform erythroderma (BCIE) is an autosomally dominant inherited disorder characterized by erythematous, erosive, and bullous skin…”
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Regulation of a Novel Human Phospholipase C, PLCε, through Membrane Targeting by Ras by Song, Chunhua, Hu, Chang-Deng, Masago, Misa, Kariya, Ken-ichi, Yamawaki-Kataoka, Yuriko, Shibatohge, Mitsushige, Wu, Dongmei, Satoh, Takaya, Kataoka, Tohru

“…Phosphoinositide-specific phospholipase C (PI-PLC) plays a pivotal role in regulation of intracellular signal transduction from various receptor molecules…”
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Angiopoietin-like protein 2 induces proinflammatory responses in peritoneal cells by Umikawa, Masato, Umikawa, Asako, Asato, Tsuyoshi, Takei, Kimiko, Matsuzaki, Goro, Kariya, Ken-ichi, Zhang, Cheng Cheng

“…Monocytes and macrophages are important effectors and regulators of inflammation, and both their differentiation and activation are regulated strictly in…”
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