Search Results - "Kariuki, Curtis H"
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Aflatoxin Exposure May Contribute to Chronic Hepatomegaly in Kenyan School Children
Published in Environmental health perspectives (01-06-2012)“…Background: Presentation with a firm type of chronic hepatomegaly of multifactorial etiology is common among school-age children in sub-Saharan Africa…”
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Spatial patterns of urinary schistosomiasis infection in a highly endemic area of coastal Kenya
Published in The American journal of tropical medicine and hygiene (01-04-2004)“…Urinary schistosomiasis remains a major contributor to the disease burden along the southern coast of Kenya. Selective identification of transmission hot spots…”
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Hepatosplenomegaly Is Associated with Low Regulatory and Th2 Responses to Schistosome Antigens in Childhood Schistosomiasis and Malaria Coinfection
Published in Infection and Immunity (01-05-2008)“…Hepatosplenomegaly among Kenyan schoolchildren has been shown to be exacerbated where there is transmission of both Schistosoma mansoni and Plasmodium…”
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Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-02-2010)“…Hepatosplenomegaly among school-aged children in sub-Saharan Africa is highly prevalent. Two of the more common aetiological agents of hepatosplenomegaly,…”
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Factors affecting human IgE and IgG responses to allergen-like Schistosoma mansoni antigens: Molecular structure and patterns of in vivo exposure
Published in International Archives of Allergy and Immunology (01-01-2007)“…The human IgE response is associated with allergy and with host defence against parasitic worms. A response to Sm22.6, the dominant IgE antigen in adult…”
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Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection
Published in Tropical medicine & international health (01-12-2007)“…Chronic exposure to malaria exacerbates Schistosoma mansoni-associated hepatosplenomegaly in school-aged children. However, residual hepatosplenomegaly after…”
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Age-adjusted Plasmodium falciparum antibody levels in school-aged children are a stable marker of microgeographical variations in exposure to Plasmodium infection
Published in BMC infectious diseases (29-06-2007)“…Amongst school-aged children living in malaria endemic areas, chronic morbidity and exacerbation of morbidity associated with other infections are often not…”
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Locating irregularly shaped clusters of infection intensity
Published in Geospatial health (01-05-2010)“…Patterns of disease may take on irregular geographic shapes, especially when features of the physical environment influence risk. Identifying these patterns…”
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Serological Responses among Individuals in Areas Where Both Schistosomiasis and Malaria Are Endemic: Cross-Reactivity between Schistosoma mansoni and Plasmodium falciparum
Published in The Journal of infectious diseases (15-04-2003)“…We examined specific immunoglobulin G1 (IgG1) and IgG3 responses to Plasmodium falciparum schizont and Schistosoma mansoni egg and worm antigens in individuals…”
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Transmission control for schistosomiasis – why it matters now
Published in Trends in parasitology (01-12-2006)“…Current population-based schistosomiasis treatment programs are a first step to reducing the global burden of Schistosoma-related disease; however, they might…”
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11
Population-Based Differences in Schistosoma mansoni- and Hepatitis C-Induced Disease
Published in The Journal of infectious diseases (01-06-2002)“…Two populations with differing histories of Schistosoma mansoni and hepatitis C infection were compared directly for severity of disease and extent of…”
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The relationship between age, sex, egg‐count and specific antibody responses against Schistosoma mansoni antigens in a Ugandan fishing community
Published in Tropical medicine & international health (01-06-2003)“…Summary In schistosomiasis endemic areas, antibody isotype responses against Schistosoma mansoni antigens vary with host age, sex and duration or intensity of…”
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Divergent Effects of Schistosoma haematobium Exposure on Intermediate-Host Snail Species Bulinus nasutus and Bulinus globosus from Coastal Kenya
Published in The American journal of tropical medicine and hygiene (05-04-2017)“…Abstract infection causes urogenital schistosomiasis, a chronic inflammatory disease that is highly prevalent in many parts of sub-Saharan Africa. Bulinid…”
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14
Associations between Anti-Schistosoma mansoni and Anti-Plasmodium falciparum Antibody Responses and Hepatosplenomegaly, in Kenyan Schoolchildren
Published in The Journal of infectious diseases (15-04-2003)“…Schoolchildren from 2 areas of Kenya, Kangundo and Kambu, have contrasting prevalences of hepatosplenomegaly, despite having similar prevalences and…”
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Posttreatment Changes in Cytokines Induced by Schistosoma mansoni Egg and Worm Antigens: Dissociation of Immunity- and Morbidity-Associated Type 2 Responses
Published in The Journal of infectious diseases (01-06-2014)“…Background. Human type 2 cytokine responsiveness to schistosome antigens increases after treatment; due either to removal of the immunosuppressive effects of…”
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Changes in IgE- and antigen-dependent histamine-release in peripheral blood of Schistosoma mansoni-infected Ugandan fishermen after treatment with praziquantel
Published in BMC immunology (21-04-2004)“…Parasite-specific IgE levels correlate with human resistance to reinfection with Schistosoma spp. after chemotherapy. Although the role of eosinophils in…”
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Prevalence and Familial Aggregation of Schistosomal Liver Morbidity in Kenya: Evaluation by New Ultrasound Criteria
Published in The Journal of infectious diseases (15-03-2001)“…Severe periportal fibrosis is not an inevitable consequence of infection with Schistosoma mansoni Genetic predisposition may be a deciding factor in the…”
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Large-scale, polymerase chain reaction-based surveillance of Schistosoma haematobium DNA in snails from transmission sites in coastal Kenya: a new tool for studying the dynamics of snail infection
Published in The American journal of tropical medicine and hygiene (01-12-2004)“…Levels of prepatent Schistosoma haematobium infection were monitored in intermediate host snails (Bulinus nasutus) collected from transmission sites in coastal…”
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Increased Human IgE Induced by Killing Schistosoma mansoni In Vivo Is Associated with Pretreatment Th2 Cytokine Responsiveness to Worm Antigens
Published in Journal of Immunology (15-10-2006)“…In schistosomiasis endemic areas, children are very susceptible to postchemotherapy reinfection, whereas adults are relatively resistant. Different studies…”
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Measuring morbidity in schistosomiasis mansoni: relationship between image pattern, portal vein diameter and portal branch thickness in large‐scale surveys using new WHO coding guidelines for ultrasound in schistosomiasis
Published in Tropical medicine & international health (01-02-2003)“…Summary Objective World Health Organization consensus meetings on ‘Ultrasound in Schistosomiasis’ in 1996 and 1997 anticipated further challenges in the…”
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