Search Results - "Karisch, Robert"

Tumor-Initiating Cells Are Rare in Many Human Tumors by Ishizawa, Kota, Rasheed, Zeshaan A., Karisch, Robert, Wang, Qiuju, Kowalski, Jeanne, Susky, Erica, Pereira, Keira, Karamboulas, Christina, Moghal, Nadeem, Rajeshkumar, N.V., Hidalgo, Manuel, Tsao, Ming, Ailles, Laurie, Waddell, Thomas K., Maitra, Anirban, Neel, Benjamin G., Matsui, William

“…Tumor-initiating cells (TICs) are defined by their ability to form tumors after xenotransplantation in immunodeficient mice and appear to be relatively rare in…”
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SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver by Takahashi, Atsushi, Tsutsumi, Ryouhei, Kikuchi, Ippei, Obuse, Chikashi, Saito, Yasuhiro, Seidi, Azadeh, Karisch, Robert, Fernandez, Minerva, Cho, Taewoo, Ohnishi, Naomi, Rozenblatt-Rosen, Orit, Meyerson, Matthew, Neel, Benjamin G., Hatakeyama, Masanori

“…Deregulation of SHP2 is associated with malignant diseases as well as developmental disorders. Although SHP2 is required for full activation of RAS signaling,…”
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Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome” by Karisch, Robert, Fernandez, Minerva, Taylor, Paul, Virtanen, Carl, St-Germain, Jonathan R., Jin, Lily L., Harris, Isaac S., Mori, Jun, Mak, Tak W., Senis, Yotis A., Östman, Arne, Moran, Michael F., Neel, Benjamin G.

“…Protein-tyrosine phosphatases (PTPs), along with protein-tyrosine kinases, play key roles in cellular signaling. All Class I PTPs contain an essential active…”
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Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis by Wiley, Sandra E., Andreyev, Alexander Y., Divakaruni, Ajit S., Karisch, Robert, Perkins, Guy, Wall, Estelle A., van der Geer, Peter, Chen, Yi‐Fan, Tsai, Ting‐Fen, Simon, Melvin I., Neel, Benjamin G., Dixon, Jack E., Murphy, Anne N.

“…Miner1 is a redox‐active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness,…”
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Integrated analysis of proteome, phosphotyrosine‐proteome, tyrosine‐kinome, and tyrosine‐phosphatome in acute myeloid leukemia by Tong, Jiefei, Helmy, Mohamed, Cavalli, Florence M. G., Jin, Lily, St‐Germain, Jonathan, Karisch, Robert, Taylor, Paul, Minden, Mark D., Taylor, Michael D., Neel, Benjamin G., Bader, Gary D., Moran, Michael F.

“…Reversible protein‐tyrosine phosphorylation is catalyzed by the antagonistic actions of protein‐tyrosine kinases (PTKs) and phosphatases (PTPs), and represents…”
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Contributions of F-BAR and SH2 Domains of Fes Protein Tyrosine Kinase for Coupling to the FcεRI Pathway in Mast Cells by McPherson, Victor A., Everingham, Stephanie, Karisch, Robert, Smith, Julie A., Udell, Christian M., Zheng, Jimin, Jia, Zongchao, Craig, Andrew W. B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Methods to monitor classical protein‐tyrosine phosphatase oxidation by Karisch, Robert, Neel, Benjamin G

“…Reactive oxygen species (ROS), particularly hydrogen peroxide (H2O2), act as intracellular second messengers in many signaling pathways. Protein‐tyrosine…”
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Efficient Syntheses of KDR Kinase Inhibitors Using a Pd-Catalyzed Tandem C−N/Suzuki Coupling as the Key Step by Fang, Yuan-Qing, Karisch, Robert, Lautens, Mark

“…A family of four potent KDR kinase inhibitors containing an indol-2-yl quinolin-2-one structure was utilizing a Pd-catalyzed tandem C−N and C−C coupling…”
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Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface by Palande, Karishma, Roovers, Onno, Gits, Judith, Verwijmeren, Carola, Iuchi, Yoshihito, Fujii, Junichi, Neel, Benjamin G, Karisch, Robert, Tavernier, Jan, Touw, Ivo P

“…Reactive oxygen species (ROS) regulate growth factor receptor signalling at least in part by inhibiting oxidation-sensitive phosphatases. An emerging concept…”
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Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058 by Chirgadze, Yuri N., Battaile, Kevin P., Likhachev, Ilya V., Balabaev, Nikolay K., Gordon, Roni D., Romanov, Vladimir, Lin, Andres, Karisch, Robert, Lam, Robert, Ruzanov, Max, Brazhnikov, Evgeniy V., Pai, Emil F., Neel, Benjamin G., Chirgadze, Nickolay Y.

“…Not provided…”
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Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058 by Chirgadze, Yuri N., Battaile, Kevin P., Likhachev, Ilya V., Balabaev, Nikolay K., Gordon, Roni D., Romanov, Vladimir, Lin, Andres, Karisch, Robert, Lam, Robert, Ruzanov, Max, Brazhnikov, Evgeniy V., Pai, Emil F., Neel, Benjamin G., Chirgadze, Nickolay Y.

“…Protein tyrosine phosphatases constitute a family of cytosolic and receptor-like signal transducing enzymes that catalyze the hydrolysis of phospho-tyrosine…”
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Global Proteomic Assessment of Classical Protein-Tyrosine Phosphatases by Karisch, Robert

“…Tyrosyl phosphorylation plays an important role in many fundamental cellular processes, including cell growth, differentiation and proliferation. The levels of…”
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Cellular and bioenergetic dysfunction induced by loss of the Wolfram Syndrome protein, Miner1, can be reversed by treatment with N-acetylcysteine by Wiley, Sandra E., Andreyev, Alexander Y., Divakaruni, Ajit S., Karisch, Robert, Perkins, Guy, van der Geer, Peter, Tsai, Ting-Fen, Simon, Melvin I., Neel, Benjamin G., Dixon, Jack E., Murphy, Anne N.

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Contributions of F-BAR and SH2 Domains of Fes Protein Tyrosine Kinase for Coupling to the FcRI Pathway in Mast Cells by McPherson, Victor A, Everingham, Stephanie, Karisch, Robert, Smith, Julie A, Udell, Christian M, Zheng, Jimin, Jia, Zongchao, B Craig, Andrew W

“…This study investigates the roles of Fer-CIP4 homology (FCH)-Bin/amphiphysin/Rvs (F-BAR) and SH2 domains of Fes protein tyrosine kinase in regulating its…”
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Contributions of F-BAR and SH2 Domains of Fes Protein Tyrosine Kinase for Coupling to the FcɛRI Pathway in Mast Cells by McPherson, Victor A., Everingham, Stephanie, Karisch, Robert, Smith, Julie A., Udell, Christian M., Zheng, Jimin, Jia, Zongchao, Craig, Andrew W. B.

“…This study investigates the roles of Fer-CIP4 homology (FCH)-Bin/amphiphysin/Rvs (F-BAR) and SH2 domains of Fes protein tyrosine kinase in regulating its…”
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Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca 2+ homeostasis by Wiley, Sandra E., Andreyev, Alexander Y., Divakaruni, Ajit S., Karisch, Robert, Perkins, Guy, Wall, Estelle A., van der Geer, Peter, Chen, Yi‐Fan, Tsai, Ting‐Fen, Simon, Melvin I., Neel, Benjamin G., Dixon, Jack E., Murphy, Anne N.

“…Miner1 is a redox‐active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness,…”
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Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells by McPherson, Victor A, Everingham, Stephanie, Karisch, Robert, Smith, Julie A, Udell, Christian M, Zheng, Jimin, Jia, Zongchao, Craig, Andrew W B

“…This study investigates the roles of Fer-CIP4 homology (FCH)-Bin/amphiphysin/Rvs (F-BAR) and SH2 domains of Fes protein tyrosine kinase in regulating its…”
Get full text