Search Results - "Karimizadeh, Elham"
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Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis
Published in BMC medical genomics (27-12-2019)“…Systemic sclerosis (SSc), a multi-organ disorder, is characterized by vascular abnormalities, dysregulation of the immune system, and fibrosis. The mechanisms…”
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MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with systemic sclerosis
Published in Autoimmunity (Chur, Switzerland) (03-04-2019)“…MicroRNAs (miRNAs) are well-known candidates for modulating the dysregulated signaling pathways during fibrosis. In this study, we investigated the expression…”
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Effects of physical form of diet on nutrient digestibility, rumen fermentation, rumination, growth performance and protozoa population of finishing lambs
Published in Animal Nutrition (01-06-2017)“…This study was conducted to compare effects of 3 physical forms of feed including mash (diet 1), pellet (diet 2) and complete feed block (CFB; diet 3) on…”
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Evaluation of the association between KIR polymorphisms and systemic sclerosis: a meta-analysis
Published in Advances in rheumatology (London, England) (10-01-2020)“…The results of investigations on the association between killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and the risk of systemic sclerosis…”
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Downregulation of Aquaporin3 in Systemic Sclerosis Dermal Fibroblasts
Published in Iranian journal of allergy, asthma, and immunology (01-06-2017)“…Skin dryness and thickening are hallmarks of systemic sclerosis (SSc) disease. Aquaporins (AQPs) are plasma membrane proteins that transport glycerol and…”
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MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis
Published in Autoimmunity (Chur, Switzerland) (18-08-2015)“…The most prominent feature of systemic sclerosis (SSc) and other diseases associated with fibrosis is the prolonged activation of fibroblasts not eliminated by…”
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Attenuation of aquaporin‐3 and epidermal growth factor receptor expression and activation in systemic sclerosis dermal fibroblasts
Published in Journal of cellular physiology (01-08-2019)“…Objectives Impaired wound healing and skin dehydration are the mainstay of systemic sclerosis (SSc) cutaneous manifestations. Aquaporin‐3 (AQP3) has a pivotal…”
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Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint
Published in Annals of the rheumatic diseases (01-06-2022)“…Neutrophils are typically the most abundant leucocyte in arthritic synovial fluid. We sought to understand changes that occur in neutrophils as they migrate…”
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c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal fibroblasts
Published in Molecular and cellular biochemistry (01-07-2015)“…It is generally accepted that the apoptosis of myofibroblasts is a crucial event in the normal wound healing. Delay in myofibroblasts apoptosis results in…”
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Inhibition of MicroRNA-21 induces apoptosis in dermal fibroblasts of patients with systemic sclerosis
Published in International journal of dermatology (01-11-2016)“…Background Prolonged activation of dermal fibroblasts is the main cause of progressive fibrosis in systemic sclerosis (SSc). It seems that inhibition of…”
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Attenuation of fibrosis with selective inhibition of c-Abl by siRNA in systemic sclerosis dermal fibroblasts
Published in Archives of Dermatological Research (01-03-2015)“…Cellular abelson (c-Abl), a non-receptor tyrosine kinase, is an important molecule in the pathogenesis of systemic sclerosis. There have been reports of…”
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Overexpression of apoptosis-related protein, survivin, in fibroblasts from patients with systemic sclerosis
Published in Irish journal of medical science (01-11-2019)“…Background/objectives Recent studies suggest that, in addition to activation and hypersecretion of matrix components, fibroblasts from patients with systemic…”
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c-Abl silencing reduced the inhibitory effects of TGF-[beta]1 on apoptosis in systemic sclerosis dermal fibroblasts
Published in Molecular and cellular biochemistry (01-07-2015)“…It is generally accepted that the apoptosis of myofibroblasts is a crucial event in the normal wound healing. Delay in myofibroblasts apoptosis results in…”
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