Search Results - "Karima, Saeed"

Interleukin‐1α and tumor necrosis factor α as an inducer for reactive‐oxygen‐species‐mediated NOD‐like receptor protein 1/NOD‐like receptor protein 3 inflammasome activation in mononuclear blood cells from individuals with chronic insomnia disorder by Aghelan, Zahra, Karima, Saeed, Khazaie, Habibolah, Abtahi, Seyed Hosein, Farokhi, Ali Reza, Rostampour, Masoumeh, Bahrehmand, Fariborz, Khodarahmi, Reza

“…Background and purpose There is some evidence that cytokines may play an important role in sleep deprivation; however, the underlying mechanisms are still…”
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Design, synthesis, molecular docking, and in vitro α-glucosidase inhibitory activities of novel 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines against yeast and rat α-glucosidase by Peytam, Fariba, Takalloobanafshi, Ghazaleh, Saadattalab, Toktam, Norouzbahari, Maryam, Emamgholipour, Zahra, Moghimi, Setareh, Firoozpour, Loghman, Bijanzadeh, Hamid Reza, Faramarzi, Mohammad Ali, Mojtabavi, Somayeh, Rashidi-Ranjbar, Parviz, Karima, Saeed, Pakraad, Roya, Foroumadi, Alireza

“…In an attempt to find novel, potent α-glucosidase inhibitors, a library of poly-substituted 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2- a ]pyrimidines 3a–ag have…”
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A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle‐related genes and miRNAs in triple‐negative breast cancer cells by Tafti, Ali, Shojaei, Samaneh, Zali, Hakimeh, Karima, Saeed, Mohammadi‐Yeganeh, Samira, Mondanizadeh, Mahdieh

“…Abstract An anticancer drug known as Rapamycin acts by inhibiting the mammalian target of the Rapamycin pathway. This agent has recently been investigated for…”
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Metastatic propagation of thyroid cancer; organ tropism and major modulators by Rajabi, Sadegh, Shakib, Heewa, Dastmalchi, Romina, Danesh-Afrooz, Afsoon, Karima, Saeed, Hedayati, Mehdi

“…Thyroid cancer, as the most prevalent endocrine malignancy, comprises nearly 1% of all cancers in the world. The metastatic propagation of thyroid cancer is…”
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Temozolomide, Simvastatin and Acetylshikonin Combination Induces Mitochondrial-Dependent Apoptosis in GBM Cells, Which Is Regulated by Autophagy by Hajiahmadi, Sima, Lorzadeh, Shahrokh, Iranpour, Rosa, Karima, Saeed, Rajabibazl, Masoumeh, Shahsavari, Zahra, Ghavami, Saeid

“…Glioblastoma multiforme (GBM) is one of the deadliest cancers. Temozolomide (TMZ) is the most common chemotherapy used for GBM patients. Recently, combination…”
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A review of highly sensitive electrochemical genosensors for microRNA detection: A novel diagnostic platform for neurodegenerative diseases diagnostics by Azimi Sanavi, Mehrnoosh, Mahdavian, Farzaneh, Dorosti, Nafiseh, Karami, Neda, Karami, Sajedeh, Khatami, Seyyed Hossein, Vakili, Omid, Taheri‐Anganeh, Mortaza, Karima, Saeed, Movahedpour, Ahmad

“…The significant role of microRNAs in regulating gene expression and in disease tracking has handed the possibility of robust and accurate diagnosis of various…”
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Serum pro‐inflammatory and anti‐inflammatory cytokines and the pathogenesis of experimental autoimmune encephalomyelitis by Jahan‐Abad, Ali J., Karima, Saeed, Shateri, Somayeh, Baram, Somayeh M., Rajaei, Shima, Morteza‐Zadeh, Parastoo, Borhani‐Haghighi, Maryam, Salari, Ali‐Akbar, Nikzamir, Abdolrahim, Gorji, Ali

“…Experimental autoimmune encephalomyelitis (EAE) as an experimental model of multiple sclerosis (MS) is characterized by demyelination, infiltration of…”
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A Low-Cost Stable SERS Substrate Based on Modified Silicon Nanowires by Rouhbakhsh, Hadi, Farkhari, Nahid, Ahmadi-kandjani, Sohrab, Karima, Saeed, Tajalli, Habib, Rashidi, Mohammad

“…In this paper, we report fabrication of a simple, stable, low-cost, and easy-to-fabricate substrate for surface enhanced Raman spectroscopy (SERS)…”
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Inhibition of MiR-155 Using Exosomal Delivery of Antagomir Can Up-Regulate PTEN in Triple Negative Breast Cancer by Razaviyan, Javad, Sirati-Sabet, Majid, Tafti, Ali, Hadavi, Razie, Karima, Saeed, Rajabibazl, Masoumeh, Mohammadi-Yeganeh, Samira

“…The most aggressive form of breast cancer (BC) is Triple-Negative BC (TNBC), with the poorest prognosis, accounting for nearly 15% of all cases. Since there is…”
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Correlation of IDH1 gene expression error in breast tumor biopsy in patients with invasive ductal carcinoma by Rostami, Behzad, Kahrizi, Sepehr, Ghorbani Yekta, Batool, Ghadyani, Rezvan, Keramatinia, Aliasghar, Hoseini, Seyed Jalil, Karima, Saeed, Nikzamir, Abdol Rahim, Mansouri, Neda, Chen, Muzi, Movafagh, Abolfazl

“…One of the most important cancers in terms of worldwide prevalence is breast tumors, which have been less investigated in correlation with the enzyme…”
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Boswellic Acids Improve Clinical Cognitive Scores and Reduce Systemic Inflammation in Patients with Mild to Moderate Alzheimer's Disease by Karima, Saeed, Aghamollaii, Vajiheh, Mahmoodi Baram, Somayeh, Balenci, Laurent, Lanctôt, Krista L, Kiss, Alex, Tafakhori, Abbas, Mahdavi, Meisam, Rajaei, Shima, Shateri, Somayeh, Yarhoseini, Amir, Mokhtari, Farzad, Fotouhi, Akbar, Riazi, Ali

“…Recent therapeutic approaches for Alzheimer's disease (AD) have had limited success. Considering the association of neuroinflammation with AD symptoms as…”
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Conformational change and GTPase activity of human tubulin: A comparative study on Alzheimer’s disease and healthy brain by Rajaei, Shima, Karima, Saeed, Sepasi Tehrani, Hessam, Shateri, Somayeh, Mahmoodi Baram, Somayeh, Mahdavi, Meisam, Mokhtari, Farzad, Alimohammadi, Alimohammad, Tafakhori, Abbas, Amiri, Abolfazl, Aghamollaii, Vajiheh, Fatemi, Hamid, Rajabibazl, Masoumeh, Kobarfard, Farzad, Gorji, Ali

“…In Alzheimer's disease (AD), the most common form of dementia, microtubules (MTs) play a pivotal role through their highly dynamic structure and instability…”
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A Case of Anti-IgLON5 Disease with Aplastic Anemia and review of the literature by Tafakhori, Abbas, Ebadi, Seyyed Reza, Amirifard, Hamed, Karima, Saeed, Hasani, Arian, Esmaeili, Nazanin

“…Anti-IgLON5 is a neurological condition with neurodegenerative and autoimmune etiology. A 64-year-old man with a 2-year history of aplastic anemia presented…”
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Design, synthesis and α-glucosidase inhibition study of novel pyridazin-based derivatives by Firoozpour, Loghman, Kazemzadeh Arasi, Faraz, Toolabi, Mahsa, Moghimi, Setareh, Armandeh, Maryam, Salmani, Farzaneh, Pakrad, Roya, Firuzpour, Hadis, Ghasemi Dogaheh, Mahtab, Ebrahimi, Seyed Esmaeil Sadat, H.M.E. Ketabforoosh, Shima, Karima, Saeed, Foroumadi, Alireza

“…In this paper, pyridazin derivatives containing different thiobenzyl moieties were synthesized and screened for their inhibitory activities against rat…”
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Isolation and Culture of Neural Stem/Progenitor Cells from the Hippocampal Dentate Gyrus of Young Adult and Aged Rats by Afhami, Mina, Behnam-Rassouli, Morteza, Gorji, Ali, Karima, Saeed, Shahpasand, Koorosh

“…Adult neural stem/progenitor cells (NSPCs) in two neurogenic areas of the brain, the dentate gyrus and the subventricular zone, are major players in adult…”
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Psychological stress effects on myelin degradation in the cuprizone‐induced model of demyelination by Meknatkhah, Sogol, Sharif Dashti, Pouya, Mousavi, Monireh‐Sadat, Zeynali, Amirbahador, Ahmadian, Shahin, Karima, Saeed, Saboury, Ali Akbar, Riazi, Gholam Hossein

“…Multiple sclerosis (MS) is known as the most common demyelinating disease worldwide in which previous studies have shown that stress is a risk factor for the…”
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Resveratrol promotes liver cell survival in mice liver-induced ischemia-reperfusion through unfolded protein response: a possible approach in liver transplantation by Totonchi, Hamidreza, Mokarram, Pooneh, Karima, Saeed, Rezaei, Ramazan, Dastghaib, Sanaz, Koohpeyma, Farhad, Noori, Shokoofe, Azarpira, Negar

“…Abstract Background Ischemia-reperfusion (I/R) of the liver is a multifactorial condition that happens during transplantation and surgery. The deleterious…”
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Kinetic and thermodynamic study of beta-Boswellic acid interaction with Tau protein investigated by surface plasmon resonance and molecular modeling methods by Haghaei, Hossein, Aref Hosseini, Seyed Rafie, Soltani, Somaieh, Fathi, Farzaneh, Mokhtari, Farzad, Karima, Saeed, Rashidi, Mohammad-Reza

“…Introduction: Beta-Boswellic acid (BBA) is a pentacyclic terpene which has been obtained from frankincense and its beneficial effects on neurodegenerative…”
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Boswellic Acids as Promising Leads in Drug Development against Alzheimer’s Disease by Haghaei, Hossein, Soltani, Somaieh, Aref Hosseini, Seyedrafie, Rashidi, Mohammad Reza, Karima, Saeed

“…Biological activity of Boswellia extract (BE) has been attributed to its main active ingredients; i.e. Boswellic acids (BAs). BE/BAs possess a promising…”
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Synthesis, α-Glucosidase inhibitory activity and docking studies of Novel Ethyl 1,2,3-triazol-4-ylmethylthio-5,6-diphenylpyridazine-4-carboxylate derivatives by Firoozpour, Loghman, Moghimi, Setareh, Salarinejad, Somayeh, Toolabi, Mahsa, Rafsanjani, Mahdi, Pakrad, Roya, Salmani, Farzaneh, Shokrolahi, Seyed Mohammad, Sadat Ebrahimi, Seyed Esmail, Karima, Saeed, Foroumadi, Alireza

“…In this work, a novel series of pyridazine-triazole hybrid molecules were prepared and evaluated as inhibitors of rat intestinal α -glucosidase enzyme. Amongst…”
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