Search Results - "Karim, Quarraisha Abdool"
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COVID-19: Impact on the HIV and Tuberculosis Response, Service Delivery, and Research in South Africa
Published in Current HIV/AIDS reports (01-02-2022)“…Purpose of Review To describe how mitigation measures against COVID-19 have impacted HIV and TB research in South Africa. Recent Findings South Africa has the…”
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HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response
Published in The Lancet (British edition) (12-09-2009)“…Summary One of the greatest challenges facing post-apartheid South Africa is the control of the concomitant HIV and tuberculosis epidemics. HIV continues to…”
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Sexually transmitted infections in pregnancy and adverse pregnancy outcomes: A retrospective cohort study
Published in International journal of gynecology and obstetrics (01-07-2024)“…Objective There is a high prevalence and incidence rate of asymptomatic sexually transmitted infections (STIs) during pregnancy in adolescent girls and young…”
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Timing of Initiation of Antiretroviral Drugs during Tuberculosis Therapy
Published in The New England journal of medicine (25-02-2010)“…The optimal timing for the initiation of antiretroviral therapy in patients with both human immunodeficiency virus infection and tuberculosis is unclear. This…”
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Integration of Antiretroviral Therapy with Tuberculosis Treatment
Published in The New England journal of medicine (20-10-2011)“…In this study from South Africa, earlier initiation of antiretroviral therapy in patients with newly diagnosed HIV infection and TB was associated with higher…”
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Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Published in Science (American Association for the Advancement of Science) (03-09-2010)“…The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of…”
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Innate Immune Activation Enhances HIV Acquisition in Women, Diminishing the Effectiveness of Tenofovir Microbicide Gel
Published in The Journal of infectious diseases (01-10-2012)“…The antiretroviral agent, tenofovir, formulated as a vaginal microbicide gel, reduces human immunodeficiency virus (HIV) acquisition by 39% in women. This…”
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Identification of adolescent girls and young women for targeted HIV prevention: a new risk scoring tool in KwaZulu Natal, South Africa
Published in Scientific reports (03-08-2020)“…The ongoing spread of human immunodeficiency virus (HIV) has driven novel interventions, such as antiretrovirals, for pre-exposure prophylaxis. Interventions…”
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Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study
Published in Sexually transmitted infections (01-12-2014)“…Sexually transmitted infections (STI) and bacterial vaginosis (BV) cause female genital tract inflammation. This inflammation, which is often present in the…”
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Implants for HIV prevention in young women: Provider perceptions and lessons learned from contraceptive implant provision
Published in PloS one (13-01-2022)“…Preventing new HIV infections, especially amongst young women, is key to ending the HIV epidemic especially in sub-Saharan Africa. Potent antiretroviral (ARV)…”
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Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection
Published in The New England journal of medicine (06-08-2015)“…Herpes simplex virus type 2 infection is a common sexually transmitted infection worldwide. Strategies to decrease transmission are needed. In this report from…”
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Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape
Published in Nature medicine (01-11-2012)“…A minority of HIV-1–infected individuals develop broadly neutralizing antibodies, which are considered an important goal of many HIV vaccine strategies. Moore…”
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Preventing HIV Infection in Women: A global Health Imperative
Published in Clinical infectious diseases (15-05-2010)“…Women account for approximately one-half of all human immunodeficiency virus (HIV) infections worldwide. Sexual transmission is the dominant mode of HIV…”
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Ratio of Monocytes to Lymphocytes in Peripheral Blood Identifies Adults at Risk of Incident Tuberculosis Among HIV-Infected Adults Initiating Antiretroviral Therapy
Published in The Journal of infectious diseases (15-02-2014)“…Background. Eight decades ago, the ratio of monocytes to lymphocytes (hereafter, the "ML ratio") was noted to affect outcomes of mycobacterial infection in…”
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Repeat HIV testing practices in the era of HIV self-testing among adults in KwaZulu-Natal, South Africa
Published in PloS one (22-02-2019)“…Repeat HIV testing is important in high HIV burden communities to enable sustainability of prevention initiatives; however, an understanding of repeat testing…”
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HIV prevention for the next decade: Appropriate, person-centred, prioritised, effective, combination prevention
Published in PLoS medicine (26-09-2022)“…UNAIDS and a broad range of partners have collaborated to establish a new set of HIV prevention targets to be achieved by 2025 as an intermediate step towards…”
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Pre-infection plasma cytokines and chemokines as predictors of HIV disease progression
Published in Scientific reports (14-02-2022)“…Previous studies have highlighted the role of pre-infection systemic inflammation on HIV acquisition risk, but the extent to which it predicts disease…”
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HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition
Published in Nature communications (19-11-2019)“…Human papillomavirus (HPV) infection correlates with higher rates of HIV acquisition, but the underlying biological mechanisms are unclear. Here we study…”
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COVID-19 and global equity for health: The good, the bad, and the wicked
Published in PLoS medicine (01-10-2021)“…[...]in wicked problems, the elusive problem formulation precludes a shared understanding of success, or even progress, by stakeholders. [...]in wicked…”
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The audacious goal to end AIDS by 2030: aspiration or reality?
Published in Journal of the International AIDS Society (01-07-2024)“…The challenge now is reaching pregnant women who do not use prenatal health services and arrive at facilities at the time of delivery with an unknown HIV…”
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