Search Results - "Karim, Nasiara"

Editorial: Natural products as an emerging therapeutic alternative for the treatment of anxiety and depression, Volume II by Khan, Ajmal, Khan, Haroon, Maione, Francesco, Karim, Nasiara

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Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo , and in-silico Approach by Karim, Nasiara, Khan, Inamullah, Khan, Waheed, Khan, Imran, Khan, Ajmal, Halim, Sobia Ahsan, Khan, Hizbullah, Hussain, Javid, Al-Harrasi, Ahmed

“…Triterpenes possess anti-inflammatory and anti-nociceptive effects. In this study anti-inflammatory activities of Asparacosin A were evaluated' using…”
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GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn by Abdelhalim, Abeer, Ahmad, Waqar, Karim, Nasiara, Khan, Imran, Chebib, Mary

“…Artemisia indica, also known as “Mugwort,” has been widely used in traditional medicines. However, few studies have investigated the effects of nonvolatile…”
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Involvement of selective GABA-A receptor subtypes in amelioration of cisplatin-induced neuropathic pain by 2’-chloro-6-methyl flavone (2’-Cl-6MF) by Karim, Nasiara, Khan, Imran, Abdelhalim, Abeer, Halim, Sobia Ahsan, Khan, Ajmal, Altaf, Nouman, Ahmad, Waqar, Ghaffar, Rukhsana, Al-Harrasi, Ahmed

“…Cisplatin-induced peripheral neuropathic pain is a common adverse effect of chemotherapy. The present study evaluated the effects of 2’-chloro-6-methylflavone…”
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Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches by Khan, Ajmal, Khan, Imran, Halim, Sobia Ahsan, Rehman, Najeeb Ur, Karim, Nasiara, Ahmad, Waqar, Khan, Majid, Csuk, Rene, Al-Harrasi, Ahmed

“…β-Boswellic acid (β-BA) and 11-keto-β-boswellic acid (β-KBA) are crucial bioactive compounds, mostly isolated from frankincense. These compounds are known for…”
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The contribution of ionotropic gabaergic and N-methyl-D-Aspartic acid receptors in the antidepressant-like effects of hispidulin by Abdelhalim, Abeer, Khan, Imran, Karim, Nasiara

“…Background: Salvia triloba, commonly known as sage belongs to Lamiaceae family, is conventionally used as a brain-enhancing tonic. The purpose of this study…”
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Bio-oriented synthesis of ibuprofen derivatives for enhancement efficacy in post-operative and chronic inflammatory pain models by Shah, Nisar Zamin, Avula, Satya Kumar, Karim, Nasiara, Islam, Nazar Ul, El-Saber Batiha, Gaber, Muhsinah, Abdullatif Bin, Khan, Ajmal, Al-Harrasi, Ahmed

“…The discovery of post-operative, chronic inflammatory pain and any gastroulcerogenic potential using well-established animal models in vivo with new…”
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Natural Products as an Emerging Therapeutic Alternative in the Treatment of Neurological Disorders by Karim, Nasiara, Abdelhalim, Heba, Gavande, Navnath, Khan, Imran, Khan, Haroon

“…Received Mar 4, 2018; Accepted Mar 4, 2018 This is an open access article distributed under the Creative Commons Attribution License, which permits…”
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Myrrhanone B and Myrrhanol B from resin of Commipohora mukul exhibit hepatoprotective effects in-vivo by Khan, Ajmal, Gul, Rehmat, Rehman, Najeeb Ur, Khan, Haroon, Karim, Nasiara, Halim, Sobia Ahsan, Ahmed, Sagheer, Al-Harrasi, Ahmed

“…Despite a large number of liver disorders, clinically useful drugs are scarce. Moreover, the available therapies are facing the challenges of efficacy and…”
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Evaluation of neuroprotective and anti-amnesic effects of Elaeagnus umbellata Thunb. On scopolamine-induced memory impairment in mice by Nazir, Nausheen, Zahoor, Muhammad, Nisar, Mohammad, Karim, Nasiara, Latif, Abdul, Ahmad, Sajjad, Uddin, Zia

“…Elaeagnus umbellata is abundantly found in Himalayan regions of Pakistan which is traditionally used to treat various health disorders. However, the…”
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Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi- incensole acetate in chronic unpredictable mild stress model of depression; behavioural and biochemical correlates by Avula, Satya Kumar, Khan, Ajmal, Halim, Sobia Ahsan, Rehman, Najeeb Ur, Karim, Nasiara, Khan, Imran, Csuk, Rene, Das, Biswanath, Al-Harrasi, Ahmed

“…In the current investigation, 5-epi-incensole (3) and 5-epi-incensole acetate (5) were synthesized from the most potent anti-depressant constituents incensole…”
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Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: Experimental and computational studies by Khan, Inamullah, Nisar, Muhammad, Ebad, Farooq, Nadeem, Said, Saeed, Muhammad, Khan, Haroon, Samiullah, Khuda, Fazli, Karim, Nasiara, Ahmad, Zia

“…Smilax china Linn. is extensively used in traditional Chinese medicine (TCM) as well as in Pakistan for several medicinal purposes including their use in…”
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GABAA receptor modulation and neuropharmacological activities of viscosine isolated from Dodonaea viscosa (Linn) by Karim, Nasiara, Irshad, Shahid, Khan, Imran, Mohammad, Akhtar, Anis, Itrat, Shah, Muhammad Raza, Khan, Inamullah, Chebib, Mary

“…The objective of the present study was to evaluate the modulation of GABA-evoked currents by the flavonoid viscosine at recombinant GABAA receptors, and…”
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α4βδ GABAA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB) by Absalom, Nathan, Eghorn, Laura F, Villumsen, Inge S, Karim, Nasiara, Bay, Tina, Olsen, Jesper V, Knudsen, Gitte M, Bräuner-Osborne, Hans, Frølund, Bente, Clausen, Rasmus P, Chebib, Mary, Wellendorph, Petrine

“…γ-Hydroxybutyric acid (GHB) binding to brain-specific high-affinity sites is well-established and proposed to explain both physiological and pharmacological…”
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Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis by Abdelhalim, Abeer, Karim, Nasiara, Chebib, Mary, Aburjai, Talal, Khan, Imran, Johnston, Graham A R, Hanrahan, Jane

“…Rosmarinus officinalis, traditionally known as rosemary, has been widely used in traditional medicines and has long been known as the herb of remembrance…”
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Vanillin derivatives as antiamnesic agents in scopolamine-induced memory impairment in mice by Gul, Qamar, Karim, Nasiara, Shoaib, Mohammad, Zahoor, Muhammad, Rahman, Mehboob Ur, Bilal, Hayat, Ullah, Riaz, Alotaibi, Amal

“…Amnesia is a major health problem prevalent in almost every part of the world specifically in old age peoples. Vanillin analogues have played an important role…”
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Potency of GABA at human recombinant GABAA receptors expressed in Xenopus oocytes: a mini review by Karim, Nasiara, Wellendorph, Petrine, Absalom, Nathan, Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary

“…GABA A receptors are members of the ligand-gated ion channel superfamily that mediate inhibitory neurotransmission in the central nervous system. They are…”
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Antiamnesic Effects of Feralolide Isolated from Aloe vera Resin Miller against Learning Impairments Induced in Mice by Khan, Imran, Mohanta, Tapan Kumar, Ihsan, Nuzhat, Halim, Sobia Ahsan, Khan, Ajmal, Rehman, Najeeb Ur, Khan, Faizullah, Khalid, Asaad, Abdalla, Ashraf N, Karim, Nasiara, Al-Harrasi, Ahmed

“…Feralolide, a dihydroisocoumarin, was isolated from the methanolic extract of resin of Aloe vera. The present study aims to investigate the in vivo ability of…”
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Antidiabetic activity and histopathological analysis of carnosol isolated from Artemisia indica linn in streptozotocin-induced diabetic rats by Khan, Imran, Ahmad, Waqar, Karim, Nasiara, Ahmad, Manzoor, Khan, Munsaib, Tariq, Shafiq Ahmad, Sultana, Nuzhat, Shah, Raza, Khan, Ajmal, Abdelhalim, Abeer

“…Diabetes mellitus is a major metabolic disorder affecting a huge population all over the world. The aim of the current study was to validate the folkloric use…”
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Antidepressent Effect of Two New Benzyl Derivatives from Wild Strawberry Fragaria vesca var. nubicola Lindl. ex Hook.f by Naz, Sadia, Farooq, Umar, Khan, Ajmal, Khan, Haroon, Karim, Nasiara, Sarwar, Rizwana, Hussain, Javid, Rauf, Abdur

“…Two new benzyl derivatives were isolated from ethyl acetate fraction of wild strawberry, var. Lindl. ex Hook.f. The structures of these compounds were…”
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