Search Results - "Karim, Ahmad F."
-
1
Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice
Published in Frontiers in cellular and infection microbiology (25-06-2024)“…Humanized mouse models are valuable tools for investigating the human immune system in response to infection and injury. We have previously described the human…”
Get full text
Journal Article -
2
Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis
Published in Scientific reports (14-06-2016)“…Chemical regulation of macrophage function is one key strategy for developing host-directed adjuvant therapies for tuberculosis (TB). A critical step to…”
Get full text
Journal Article -
3
Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells
Published in PloS one (25-11-2013)“…Tuberculosis (TB) is the leading cause of mortality among those infected with human immunodeficiency virus (HIV-1) worldwide. HIV-1 load and heterogeneity are…”
Get full text
Journal Article -
4
Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAIL
Published in The Journal of immunology (1950) (15-01-2016)“…Mycobacterium tuberculosis cell wall glycolipid, lipoarabinomannan, can inhibit CD4(+) T cell activation by downregulating the phosphorylation of key proximal…”
Get full text
Journal Article -
5
Proteomics and Network Analyses Reveal Inhibition of Akt‐mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose‐Capped Lipoarabinomannan
Published in Proteomics (Weinheim) (01-11-2017)“…Mycobacterium tuberculosis (Mtb) cell wall glycolipid mannose‐capped lipoarabinomannan (ManLAM) inhibits CD4+ T‐cell activation by inhibiting proximal T‐cell…”
Get full text
Journal Article -
6
TLR2 engagement on CD4+ T cells enhances effector functions and protective responses to Mycobacterium tuberculosis
Published in European journal of immunology (01-05-2014)“…We have previously demonstrated that mycobacterial lipoproteins engage TLR2 on human CD4+ T cells and upregulate TCR‐triggered IFN‐γ secretion and cell…”
Get full text
Journal Article -
7
Combined Effects of Type-II Diabetes Mellitus and Cigarette Smoking Increase the Risk of Cardiovascular Complications
Published in Dubai diabetes and endocrinology journal (01-03-2019)“…Premature atherosclerosis may result from conditions such as hypercholesterolaemia, diabetes, hypertension and cigarette smoking. Any of these four conditions…”
Get full text
Journal Article -
8
TLR2 engagement on CD4 super(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis
Published in European journal of immunology (01-05-2014)“…We have previously demonstrated that mycobacterial lipoproteins engage TLR2 on human CD4 super(+) T cells and upregulate TCR-triggered IFN-[gamma] secretion…”
Get full text
Journal Article -
9
Mycobacterial Phosphatidylinositol Mannoside 6 (PIM6) Up-Regulates TCR-Triggered HIV-1 Replication in CD4+ T Cells: e80938
Published in PloS one (01-11-2013)“…Tuberculosis (TB) is the leading cause of mortality among those infected with human immunodeficiency virus (HIV-1) worldwide. HIV-1 load and heterogeneity are…”
Get full text
Journal Article -
10
The Effect Spouse Support and Mental Attitude on The Trade-fish Economic Recovery
Published in Jurnal manajemen (17-08-2021)“…The aimed of this research was to measure the effect of partner support and mental attitude on the economic recovery of salted fish traders in the Lamekongga…”
Get full text
Journal Article