Search Results - "Karikari, Collins A"

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer by Shain, A. Hunter, Giacomini, Craig P, Matsukuma, Karen, Karikari, Collins A, Bashyam, Murali D, Hidalgo, Manuel, Maitra, Anirban, Pollack, Jonathan R

“…Defining the molecular genetic alterations underlying pancreatic cancer may provide unique therapeutic insight for this deadly disease. Toward this goal, we…”
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Aberrant MicroRNA-155 Expression Is an Early Event in the Multistep Progression of Pancreatic Adenocarcinoma by Ryu, Ji Kon, Hong, Seung-Mo, Karikari, Collins A, Hruban, Ralph H, Goggins, Michael G, Maitra, Anirban

“…Abstract Background/Aims: Pancreatic intraepithelial neoplasia (PanIN) is the most common noninvasive precursor to invasive pancreatic adenocarcinoma…”
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SMURF1 amplification promotes invasiveness in pancreatic cancer by Kwei, Kevin A, Shain, A Hunter, Bair, Ryan, Montgomery, Kelli, Karikari, Collins A, van de Rijn, Matt, Hidalgo, Manuel, Maitra, Anirban, Bashyam, Murali D, Pollack, Jonathan R

“…Pancreatic cancer is a deadly disease, and new therapeutic targets are urgently needed. We previously identified DNA amplification at 7q21-q22 in pancreatic…”
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Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer by Kwei, Kevin A, Bashyam, Murali D, Kao, Jessica, Ratheesh, Raman, Reddy, Edumakanti C, Kim, Young H, Montgomery, Kelli, Giacomini, Craig P, Choi, Yoon-La, Chatterjee, Sreejata, Karikari, Collins A, Salari, Keyan, Wang, Pei, Hernandez-Boussard, Tina, Swarnalata, Gowrishankar, van de Rijn, Matt, Maitra, Anirban, Pollack, Jonathan R

“…Pancreatobiliary cancers have among the highest mortality rates of any cancer type. Discovering the full spectrum of molecular genetic alterations may suggest…”
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Array-Based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic Cancer by Bashyam, Murali D., Bair, Ryan, Kim, Young H., Wang, Pei, Hernandez-Boussard, Tina, Karikari, Collins A., Tibshirani, Robert, Maitra, Anirban, Pollack, Jonathan R.

“…Pancreatic cancer, the fourth leading cause of cancer death in the United States, is frequently associated with the amplification and deletion of specific…”
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Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein by Karikari, Collins A, Roy, Indrajit, Tryggestad, Eric, Feldmann, Georg, Pinilla, Clemencia, Welsh, Kate, Reed, John C, Armour, Elwood P, Wong, John, Herman, Joseph, Rakheja, Dinesh, Maitra, Anirban

“…Resistance to apoptosis is a hallmark of many solid tumors, including pancreatic cancers, and may be the underlying basis for the suboptimal response to…”
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In vivo and in vitro propagation of intraductal papillary mucinous neoplasms by Kamiyama, Hirohiko, Kamiyama, Mihoko, Hong, Seung-Mo, Karikari, Collins A, Lin, Ming-Tseh, Borges, Michael W, Griffith, Margaret, Young, Angela, Norris-Kirby, Alexis, Lubek, Conrad, Mizuma, Masamichi, Feldmann, Georg, Shi, Chanjuan, Liang, Hong, Goggins, Michael G, Maitra, Anirban, Hruban, Ralph H, Eshleman, James R

“…Intraductal papillary mucinous neoplasms (IPMNs) are one of the three known curable precursor lesions of invasive pancreatic ductal adenocarcinoma, an almost…”
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Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers by Karikari, Collins A, Mullendore, Michael, Eshleman, James R, Argani, Pedram, Leoni, Lorenzo M, Chattopadhyay, Shrikanta, Hidalgo, Manuel, Maitra, Anirban

“…The p16 INK4A /CDKN2A gene on chromosome 9p21 is a site of frequent allelic loss in human cancers, and in a subset of cases, homozygous deletions at this locus…”
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The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target by Koorstra, Jan-Bart M., Karikari, Collins, Feldmann, Georg, Bisht, Savita, Leal-Rojas, Pamela, Offerhaus, G. Johann A., Alvarez, Hector, Maitra, Anirban

“…Pancreatic cancer is a near uniformly lethal disease and a better understanding of the molecular basis of this malignancy may lead to improved therapeutics…”
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Personalized Chemotherapy Profiling Using Cancer Cell Lines from Selectable Mice by KAMIYAMA, Hirohiko, RAUENZAHN, Sherri, KARANAM, Balasubramanyam, HONG LIANG, MULLENDORE, Michael E, GUANGLAN MO, HIDALGO, Manuel, JAFFEE, Elizabeth, HRUBAN, Ralph H, JINNAH, H. A, RODEN, Richard B. S, JIMENO, Antonio, JOONG SUP SHIM, LIU, Jun O, MAITRA, Anirban, ESHLEMAN, James R, KARIKARI, Collins A, FELDMANN, Georg, LI HUA, KAMIYAMA, Mihoko, SCHULER, F. William, LIN, Ming-Tseh, BEATY, Robert M

“…High-throughput chemosensitivity testing of low-passage cancer cell lines can be used to prioritize agents for personalized chemotherapy. However, generating…”
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Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1 by Singh, Mansher, Pandey, Ambarish, Karikari, Collins A., Singh, Gayatri, Rakheja, Dinesh

“…Curcumin is a naturally occurring polyphenolic compound found in the turmeric, which is used as food additive in Indian cooking and as a therapeutic agent in…”
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Mitochondrial DNA mutations in pancreatic cancer by Kassauei, Keyanoosh, Habbe, Nils, Mullendore, Michael E, Karikari, Collins A, Maitra, Anirban, Feldmann, Georg

“…Somatic mutations of mitochondrial DNA (mtDNA) are increasingly being recognized in many human cancers, but automated sequencing of 16.5 kb of DNA poses an…”
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Abstract 3930: Integrative genomic analysis reveals SWI/SNF chromatin remodeling complex to be a TGFβ-mediating tumor suppressor pathway in pancreatic cancer by Shain, Alan H., Matsukuma, Karen, Giacomini, Craig, Karikari, Collins A., Hidalgo, Manuel, Maitra, Anirban, Pollack, Jonathan R.

“…Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer deaths in the developed world. A more complete characterization of molecular…”
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Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer by Shain, A. Hunter, Giacomini, Craig P., Matsukuma, Karen, Karikari, Collins A., Bashyam, Murali D., Hidalgo, Manuel, Maitra, Anirban, Pollack, Jonathan R.

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Genomic Profiling Identifies GATA6 as a Candidate Oncogene Amplified in Pancreatobiliary Cancer: e1000081 by Kwei, Kevin A, Bashyam, Murali D, Kao, Jessica, Ratheesh, Raman, Reddy, Edumakanti C, Kim, Young H, Montgomery, Kelli, Giacomini, Craig P, Choi, Yoon-La, Chatterjee, Sreejata, Karikari, Collins A, Salari, Keyan, Wang, Pei, Hernandez-Boussard, Tina, Swarnalata, Gowrishankar, Rijn, Matt vande, Maitra, Anirban, Pollack, Jonathan R

“…Pancreatobiliary cancers have among the highest mortality rates of any cancer type. Discovering the full spectrum of molecular genetic alterations may suggest…”
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Array-Based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic Cancer1 by Bashyam, Murali D, Bair, Ryan, Kim, Young H, Wang, Pei, Hernandez-Boussard, Tina, Karikari, Collins A, Tibshirani, Robert, Maitra, Anirban, Pollack, Jonathan R

“…Pancreatic cancer, the fourth leading cause of cancer death in the United States, is frequently associated with the amplification and deletion of specific…”
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