Search Results - "Karhula, S.S."

3D histopathological grading of osteochondral tissue using contrast-enhanced micro-computed tomography by Nieminen, H.J, Gahunia, H.K, Pritzker, K.P.H, Ylitalo, T, Rieppo, L, Karhula, S.S, Lehenkari, P, Hæggström, E, Saarakkala, S

“…Summary Objective Histopathological grading of osteochondral (OC) tissue is widely used in osteoarthritis (OA) research, and it is relatively common in…”
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3D analysis of chondron morphology of human and rat articular cartilage from micro-computed tomography by Kestilä, I, Finnilä, M.A, Karhula, S.S, Rieppo, L, Lehenkari, P, Thevenot, J, Saarakkala, S

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Synchrotron Micro-computed Tomography Reveals Increased Osteocyte Volume in Subchondral Bone with Osteoarthritis Severity by Finnilä, M.A, Karhula, S.S, Cooper, D.M, Belev, G, Nieminen, H.J, Korhonen, R.K, Lehenkari, P.P, Saarakkala, S

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Heterogeneity in Extracellular Matrix of Articular Cartilage as a Function of Osteoarthritis Progression as Characterized by Micro-CT by Ylitalo, T.J, Finnilä, M, Karhula, S.S, Valkealahti, M, Lehenkari, P, Hæggström, E, Pritzker, K.P, Saarakkala, S, Nieminen, H.J

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Automatic 3D Selection, Segmentation, and Analysis of Human Articular Cartilage Chondrons from Micro-computed Tomography in vitro by Kestilä, I, Thevenot, J.P, Finnilä, M.A, Karhula, S.S, Hadjab, I, Kauppinen, S, Garon, M, Quenneville, E, Rieppo, L, Pritzker, K.P, Buschmann, M.D, Nieminen, H.J, Saarakkala, S

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Volumetric Analysis of Tidemark and Vessel Perforations through Calcified Cartilage from Micro-computed Tomography: Associations with Osteoarthritis Stage by Kauppinen, S, Karhula, S.S, Thevenot, J, Ylitalo, T, Rieppo, L, Kestilä, I, Hadjab, I, Finnilä, M.A, Quenneville, E, Garon, M, Gahunia, H.K, Pritzker, K.P, Buschmann, M, Nieminen, H.J, Saarakkala, S

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Changes in mineralization in calcified cartilage and subchondral bone plate during osteoarthritis progression by Gupta, S. Das, Finnilä, M.A., Karhula, S.S., Korhonen, R., Thambyah, A., Rieppo, L., Saarakkala, S.

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Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro-computed tomography by Rytky, S.J.O., Tiulpin, A., Frondelius, T., Finnilä, M.A.J., Karhula, S.S., Leino, J., Pritzker, K.P.H., Valkealahti, M., Lehenkari, P., Joukainen, A., Kröger, H., Nieminen, H.J., Saarakkala, S.

“…To develop and validate a machine learning (ML) approach for automatic three-dimensional (3D) histopathological grading of osteochondral samples imaged with…”
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3D morphometric analysis of calcified cartilage properties using micro-computed tomography by Kauppinen, S., Karhula, S.S., Thevenot, J., Ylitalo, T., Rieppo, L., Kestilä, I., Haapea, M., Hadjab, I., Finnilä, M.A., Quenneville, E., Garon, M., Gahunia, H.K., Pritzker, K.P.H., Buschmann, M.D., Saarakkala, S., Nieminen, H.J.

“…Our aim is to establish methods for quantifying morphometric properties of calcified cartilage (CC) from micro-computed tomography (μCT). Furthermore, we…”
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3D analysis of local grey-level variance from micro-CT images is associated with osteocyte cellularity in human osteoarthritic subchondral bone by Karhula, S.S., Finnilä, M.A., Cooper, D.M., Miller, D., Valkealahti, M., Joukainen, A., Lehenkari, P., Kröger, H., Korhonen, R.K., Nieminen, H.J., Saarakkala, S.

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3D osteocyte morphology and volume of chondrocyte clusters are modulated with osteoarthritis severity by Finnilä, M.A., Karhula, S.S., Cooper, D.M., Valkealahti, M., Joukainen, A., Miller, D., Nieminen, H., Kröger, H., Korhonen, R.K., Lehenkari, P.P., Saarakkala, S.

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In vitro method for 3D morphometry of human articular cartilage chondrons based on micro-computed tomography by Kestilä, I., Thevenot, J., Finnilä, M.A., Karhula, S.S., Hadjab, I., Kauppinen, S., Garon, M., Quenneville, E., Haapea, M., Rieppo, L., Pritzker, K.P., Buschmann, M.D., Nieminen, H.J., Saarakkala, S.

“…The aims of this study were: to 1) develop a novel sample processing protocol to visualize human articular cartilage (AC) chondrons using micro-computed…”
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Electromechanical properties of human osteoarthritic and asymptomatic articular cartilage are sensitive and early detectors of degeneration by Hadjab, I., Sim, S., Karhula, S.S., Kauppinen, S., Garon, M., Quenneville, E., Lavigne, P., Lehenkari, P.P., Saarakkala, S., Buschmann, M.D.

“…To evaluate cross-correlations of ex vivo electromechanical properties with cartilage and subchondral bone plate thickness, as well as their sensitivity and…”
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