Search Results - "Karhula, S. S."

Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: A pilot study by Das Gupta, Shuvashis, Finnilä, Mikko A.J., Karhula, Sakari S., Kauppinen, Sami, Joukainen, Antti, Kröger, Heikki, Korhonen, Rami K., Thambyah, Ashvin, Rieppo, Lassi, Saarakkala, Simo

“…This study investigates the influence of osteoarthritis (OA) disease severity on the bio-composition of the osteochondral junction at the human tibial plateau…”
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Effect of centrifugal force on the development of articular neocartilage with bovine primary chondrocytes by Prittinen, J., Ylärinne, J., Piltti, J., Karhula, S. S., Rieppo, L., Ojanen, S. P., Korhonen, R. K., Saarakkala, S., Lammi, M. J., Qu, C.

“…A lot has been invested into understanding how to assemble cartilage tissue in vitro and various designs have been developed to manufacture cartilage tissue…”
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Effects of Articular Cartilage Constituents on Phosphotungstic Acid Enhanced Micro-Computed Tomography by Karhula, Sakari S, Finnilä, Mikko A, Lammi, Mikko J, Ylärinne, Janne H, Kauppinen, Sami, Rieppo, Lassi, Pritzker, Kenneth P H, Nieminen, Heikki J, Saarakkala, Simo

“…Contrast-enhanced micro-computed tomography (CEμCT) with phosphotungstic acid (PTA) has shown potential for detecting collagen distribution of articular…”
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Determining collagen distribution in articular cartilage using contrast-enhanced micro-computed tomography by Nieminen, H.J, Ylitalo, T, Karhula, S, Suuronen, J.-P, Kauppinen, S, Serimaa, R, Hæggström, E, Pritzker, K.P.H, Valkealahti, M, Lehenkari, P, Finnilä, M, Saarakkala, S

“…Summary Objective Collagen distribution within articular cartilage (AC) is typically evaluated from histological sections, e.g., using collagen staining and…”
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3D histopathological grading of osteochondral tissue using contrast-enhanced micro-computed tomography by Nieminen, H.J, Gahunia, H.K, Pritzker, K.P.H, Ylitalo, T, Rieppo, L, Karhula, S.S, Lehenkari, P, Hæggström, E, Saarakkala, S

“…Summary Objective Histopathological grading of osteochondral (OC) tissue is widely used in osteoarthritis (OA) research, and it is relatively common in…”
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Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro-computed tomography by Rytky, S.J.O., Tiulpin, A., Frondelius, T., Finnilä, M.A.J., Karhula, S.S., Leino, J., Pritzker, K.P.H., Valkealahti, M., Lehenkari, P., Joukainen, A., Kröger, H., Nieminen, H.J., Saarakkala, S.

“…To develop and validate a machine learning (ML) approach for automatic three-dimensional (3D) histopathological grading of osteochondral samples imaged with…”
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3D morphometric analysis of calcified cartilage properties using micro-computed tomography by Kauppinen, S., Karhula, S.S., Thevenot, J., Ylitalo, T., Rieppo, L., Kestilä, I., Haapea, M., Hadjab, I., Finnilä, M.A., Quenneville, E., Garon, M., Gahunia, H.K., Pritzker, K.P.H., Buschmann, M.D., Saarakkala, S., Nieminen, H.J.

“…Our aim is to establish methods for quantifying morphometric properties of calcified cartilage (CC) from micro-computed tomography (μCT). Furthermore, we…”
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In vitro method for 3D morphometry of human articular cartilage chondrons based on micro-computed tomography by Kestilä, I., Thevenot, J., Finnilä, M.A., Karhula, S.S., Hadjab, I., Kauppinen, S., Garon, M., Quenneville, E., Haapea, M., Rieppo, L., Pritzker, K.P., Buschmann, M.D., Nieminen, H.J., Saarakkala, S.

“…The aims of this study were: to 1) develop a novel sample processing protocol to visualize human articular cartilage (AC) chondrons using micro-computed…”
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Electromechanical properties of human osteoarthritic and asymptomatic articular cartilage are sensitive and early detectors of degeneration by Hadjab, I., Sim, S., Karhula, S.S., Kauppinen, S., Garon, M., Quenneville, E., Lavigne, P., Lehenkari, P.P., Saarakkala, S., Buschmann, M.D.

“…To evaluate cross-correlations of ex vivo electromechanical properties with cartilage and subchondral bone plate thickness, as well as their sensitivity and…”
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Quantifying Subresolution 3D Morphology of Bone with Clinical Computed Tomography by Karhula, S. S., Finnilä, M. A. J., Rytky, S. J. O., Cooper, D. M., Thevenot, J., Valkealahti, M., Pritzker, K. P. H., Haapea, M., Joukainen, A., Lehenkari, P., Kröger, H., Korhonen, R. K., Nieminen, H. J., Saarakkala, S.

“…The aim of this study was to quantify sub-resolution trabecular bone morphometrics, which are also related to osteoarthritis (OA), from clinical resolution…”
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3D-histopathological grading of articular cartilage using contrast-enhanced high-resolution micro-CT by Gahunia, H, Karhula, S, Ylitalo, T, Hæggström, E, Pritzker, K.P, Saarakkala, S, Nieminen, H.J

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Determination of Extracellular Matrix Orientation of Articular Cartilage in 3D Using Micro-Computed Tomography by Rieppo, L, Karhula, S, Thevenot, J, Hadjab, I, Quenneville, E, Garon, M, Buschmann, M.D, Nieminen, H.J, Saarakkala, S

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Surface characterization of degenerated articular cartilage surface by contrast-enhanced micro-computed tomography by Ylitalo, T.J, Finnilä, M, Karhula, S, Hæggström, E, Pritzker, K.P, Saarakkala, S, Nieminen, H.J

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Semi-automatic 3D surface characterization of degenerated articular cartilage by Ylitalo, T.J, Gahunia, H, Karhula, S, Finnilä, M, Suhonen, H, Hæggström, E, Pritzker, K.P, Saarakkala, S, Niemimen, H.J

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Cellulose nanofiber aerogels impregnated with bio-based epoxy using vacuum infusion: Structure, orientation and mechanical properties by Nissilä, Tuukka, Karhula, Sakari S., Saarakkala, Simo, Oksman, Kristiina

“…Cellulose nanofiber aerogels were used as preforms that were impregnated with a bio-epoxy resin via a widely used vacuum infusion process. The simple and…”
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Cerebral tissue oxygenation response to brain irradiation measured during clinical radiotherapy by Myllylä, Teemu, Korhonen, Vesa, Karthikeyan, Priya, Honka, Ulriika, Lohela, Jesse, Inget, Kalle, Ferdinando, Hany, Karhula, Sakari S., Nikkinen, Juha

“…Cancer therapy treatments produce extensive changes in the physiological and morphological properties of tissues, which are also individual dependent…”
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Micro-CT Analysis of Bone Healing in Rabbit Calvarial Critical-Sized Defects with Solid Bioactive Glass, Tricalcium Phosphate Granules or Autogenous Bone by Lappalainen, Olli-Pekka, Karhula, Sakari S, Haapea, Marianne, Kauppinen, Sami, Finnilä, Mikko, Saarakkala, Simo, Serlo, Willy, Sándor, George K

“…The purpose of the present study was to evaluate bone healing in rabbit critical-sized calvarial defects using two different synthetic scaffold materials,…”
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Clinical Super-Resolution Computed Tomography of Bone Microstructure: Application in Musculoskeletal and Dental Imaging by Rytky, Santeri J. O., Tiulpin, Aleksei, Finnilä, Mikko A. J., Karhula, Sakari S., Sipola, Annina, Kurttila, Väinö, Valkealahti, Maarit, Lehenkari, Petri, Joukainen, Antti, Kröger, Heikki, Korhonen, Rami K., Saarakkala, Simo, Niinimäki, Jaakko

“…Purpose Clinical cone-beam computed tomography (CBCT) devices are limited to imaging features of half a millimeter in size and cannot quantify the tissue…”
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An Automatic Regularization Method: An Application for 3-D X-Ray Micro-CT Reconstruction Using Sparse Data by Purisha, Zenith, Karhula, Sakari S., Ketola, Juuso H., Rimpelainen, Juho, Nieminen, Miika T., Saarakkala, Simo, Kroger, Heikki, Siltanen, Samuli

“…X-ray tomography is a reliable tool for determining the inner structure of 3-D object with penetrating X-rays. However, traditional reconstruction methods,…”
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Bright ultrashort echo time SWIFT MRI signal at the osteochondral junction is not located in the calcified cartilage by Nykänen, Olli, Leskinen, Henri P. P., Finnilä, Mikko A. J., Karhula, Sakari S., Turunen, Mikael J., Töyräs, Juha, Saarakkala, Simo, Nissi, Mikko J.

“…In this study, we aimed to precisely localize the hyperintense signal that is generated at the osteochondral junction when using ultrashort echo time magnetic…”
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