Search Results - "Kardooni, Hoda"
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CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-β Signaling in Prostate Cancer
Published in Cancers (28-05-2018)“…The gene encodes a secreted protein, Dkk-3, that inhibits prostate tumor growth and metastasis. is downregulated by promoter methylation in many types of…”
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Journal Article -
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Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1
Published in Oncogene (01-09-2018)“…Aberrant transforming growth factor–β (TGF-β) signaling is a hallmark of the stromal microenvironment in cancer. Dickkopf-3 (Dkk-3), shown to inhibit TGF-β…”
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Journal Article -
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Abstract B33: Promoter hypermethylation in pediatric malignant astrocytoma: Identification of candidate genes and therapeutic possibilities
Published in Cancer research (Chicago, Ill.) (01-07-2013)“…Brain tumors account for the most frequent type of solid tumors and the main cause of cancer deaths in children. Recent investigations have suggested that many…”
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Journal Article -
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EG-01EPIGENETIC INACTIVATION OF ARGININE BIOSYNTHESIS PATHWAY IN PAEDIATRIC HIGH GRADE GLIOMA
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2014)“…Aberrant cellular metabolism contributes significantly to the growth and proliferation of several tumour types. Identification of genes that control critical…”
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Journal Article -
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O12GENETIC CHARACTERISATION OF PI3K-RELATED PATHWAYS IN PAEDIATRIC GBM IN VITRO
Published in Neuro-oncology (Charlottesville, Va.) (01-10-2014)“…INTRODUCTION: A major obstacle to the development and validation of new therapeutic strategies (including small-molecule inhibitors of PI3K signalling) in…”
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Journal Article -
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Epigenetic silencing of gene expression in paediatric malignant astrocytoma
Published 01-01-2015“…Brain tumours account for the most frequent type of solid tumours among children. Despite advances in surgery and chemotherapy, brain tumours are still the…”
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Dissertation -
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EG-01 EPIGENETIC INACTIVATION OF ARGININE BIOSYNTHESIS PATHWAY IN PAEDIATRIC HIGH GRADE GLIOMA
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2014)“…Aberrant cellular metabolism contributes significantly to the growth and proliferation of several tumour types. Identification of genes that control critical…”
Get full text
Journal Article -
8
O12 GENETIC CHARACTERISATION OF PI3K-RELATED PATHWAYS IN PAEDIATRIC GBM IN VITRO
Published in Neuro-oncology (Charlottesville, Va.) (01-10-2014)“…INTRODUCTION: A major obstacle to the development and validation of new therapeutic strategies (including small-molecule inhibitors of PI3K signalling) in…”
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Journal Article