Search Results - "Kardel, Melanie D."

Modeling human hematopoietic cell development from pluripotent stem cells by Kardel, Melanie D, Eaves, Connie J

“…Understanding the steps and cues that allow hematopoietic cells to be generated during development holds great clinical as well as biological interest…”
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Alkaline Phosphatase‐Positive Colony Formation Is a Sensitive, Specific, and Quantitative Indicator of Undifferentiated Human Embryonic Stem Cells by O'Connor, Michael D., Kardel, Melanie D., Iosfina, Ioulia, Youssef, David, Lu, Min, Li, Michael M., Vercauteren, Suzanne, Nagy, Andras, Eaves, Connie J.

“…Human embryonic stem cells (hESCs) can be maintained in vitro as immortal pluripotent cells but remain responsive to many differentiation‐inducing signals…”
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Functional assays for human embryonic stem cell pluripotency by O'Connor, Michael D, Kardel, Melanie D, Eaves, Connie J

“…Realizing the potential that human embryonic stem cells (hESCs) hold, both for the advancement of biomedical science and the development of new treatments for…”
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Enhanced generation of hematopoietic cells from human hepatocarcinoma cell−stimulated human embryonic and induced pluripotent stem cells by Lu, Min, Kardel, Melanie D, O'Connor, Michael D, Eaves, Connie J

“…Objective Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) constitute unique sources of pluripotent cells, although the…”
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Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β‐thalassemia patient by Tubsuwan, Alisa, Abed, Soumeya, Deichmann, Annette, Kardel, Melanie D., Bartholomä, Cynthia, Cheung, Alice, Negre, Olivier, Kadri, Zahra, Fucharoen, Suthat, Kalle, Christof, Payen, Emmanuel, Chrétien, Stany, Schmidt, Manfred, Eaves, Connie J., Leboulch, Philippe, Maouche‐Chrétien, Leïla

“…ABSTRACT A patient with βE/β0‐thalassemia major was converted to transfusion‐independence 4.5 years ago by lentiviral gene transfer in hematopoietic stem cells…”
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CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L by Banting, Graham S., Barak, Orr, Ames, Tanya M., Burnham, Amanda C., Kardel, Melanie D., Cooch, Neil S., Davidson, Courtney E., Godbout, Roseline, McDermid, Heather E., Shiekhattar, Ramin

“…Chromatin remodeling complexes play critical roles in development. Here we describe a transcription factor, CECR2, which is involved in neurulation and…”
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Three duplicons form a novel chimeric transcription unit in the pericentromeric region of chromosome 22q11 by BRIDGLAND, Lindsay, FOOTZ, Tim K, KARDEL, Melanie D, ALI RIAZI, M, MCDERMID, Heather E

“…Pericentromeric regions of human chromosomes are preferential sites for the integration of duplicated DNA, or "duplicons", which often contain gene fragments…”
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Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted [beta]-thalassemia patient by Tubsuwan, Alisa, Abed, Soumeya, Deichmann, Annette, Kardel, Melanie D, Bartholoma, Cynthia, Cheung, Alice, Negre, Olivier, Kadri, Zahra, Fucharoen, Suthat, Kalle, Christof, Payen, Emmanuel, Chretien, Stany, Schmidt, Manfred, Eaves, Connie J, Leboulch, Philippe, Maouche-Chretien, Leïla

“…A patient with [beta]E/[beta]0-thalassemia major was converted to transfusion-independence 4.5 years ago by lentiviral gene transfer in hematopoietic stem…”
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