Search Results - "Karchewski, Laurie"

Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice by Weibel, Raphaël, Reiss, David, Karchewski, Laurie, Gardon, Olivier, Matifas, Audrey, Filliol, Dominique, Becker, Jérôme A J, Wood, John N, Kieffer, Brigitte L, Gaveriaux-Ruff, Claire

“…Opiates are powerful drugs to treat severe pain, and act via mu opioid receptors distributed throughout the nervous system. Their clinical use is hampered by…”
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Partial Peripheral Nerve Injury Promotes a Selective Loss of GABAergic Inhibition in the Superficial Dorsal Horn of the Spinal Cord by Moore, Kimberly A, Kohno, Tatsuro, Karchewski, Laurie A, Scholz, Joachim, Baba, Hiroshi, Woolf, Clifford J

“…To clarify whether inhibitory transmission in the superficial dorsal horn of the spinal cord is reduced after peripheral nerve injury, we have studied synaptic…”
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Inflammatory pain is enhanced in delta opioid receptor-knockout mice by Gavériaux-Ruff, Claire, Karchewski, Laurie A., Hever, Xavier, Matifas, Audrey, Kieffer, Brigitte L.

“…To examine the involvement of opioid receptors in inflammatory pain, we compared Complete Freund’s Adjuvant‐induced hyperalgesia in mice lacking mu, delta or…”
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Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury by Costigan, Michael, Befort, Katia, Karchewski, Laurie, Griffin, Robert S, D'Urso, Donatella, Allchorne, Andrew, Sitarski, Joanne, Mannion, James W, Pratt, Richard E, Woolf, Clifford J

“…Rat oligonucleotide microarrays were used to detect changes in gene expression in the dorsal root ganglion (DRG) 3 days following sciatic nerve transection…”
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Peripheral axonal injury results in reduced μ opioid receptor pre- and post-synaptic action in the spinal cord by Kohno, Tatsuro, Ji, Ru-Rong, Ito, Nobuko, Allchorne, Andrew J., Befort, Katia, Karchewski, Laurie A., Woolf, Clifford J.

“…In both the spared nerve injury (SNI) and spinal nerve ligation (SNL) rat peripheral neuropathic pain models the presynaptic inhibitory effect of the μ opioid…”
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Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons by Karchewski, Laurie A., Bloechlinger, Stefan, Woolf, Clifford J.

“…The peripheral benzodiazepine receptor (PBR), a benzodiazepine but not γ‐aminobutyric acid‐binding mitochondrial membrane protein, has roles in steroid…”
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Upregulation of the Voltage-Gated Sodium Channel β2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J., Karchewski, Laurie, Tate, Simon N., Isom, Lori L., Woolf, Clifford J., Gilliard, Nicolas, Spahn, Donat R., Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Calpain-Cleaved Collapsin Response Mediator Protein-3 Induces Neuronal Death after Glutamate Toxicity and Cerebral Ischemia by Hou, Sheng T, Jiang, Susan X, Desbois, Angele, Huang, Deqi, Kelly, John, Tessier, Luc, Karchewski, Laurie, Kappler, Joachim

“…Collapsin response mediator proteins (CRMPs) mediate growth cone collapse during development, but their roles in adult brains are not clear. Here we report the…”
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Dynamic changes in glypican-1 expression in dorsal root ganglion neurons after peripheral and central axonal injury by Bloechlinger, Stefan, Karchewski, Laurie A., Woolf, Clifford J.

“…Glypican‐1, a glycosyl phosphatidyl inositol (GPI)‐anchored heparan sulphate proteoglycan expressed in the developing and mature cells of the central nervous…”
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DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties by Samad, Tarek A, Srinivasan, Ashok, Karchewski, Laurie A, Jeong, Sung-Jin, Campagna, Jason A, Ji, Ru-Rong, Fabrizio, David A, Zhang, Ying, Lin, Herbert Y, Bell, Esther, Woolf, Clifford J

“…DRG11, a transcription factor expressed in embryonic dorsal root ganglion (DRG) and dorsal horn neurons, has a role in the development of sensory circuits. We…”
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Neuropilin 2 deficiency does not affect cortical neuronal viability in response to oxygen–glucose-deprivation and transient middle cerebral artery occlusion by Hou, Sheng T., Jiang, Susan X., Slinn, Jacqueline, O’Hare, Michael, Karchewski, Laurie

“…Neuropilin 2 (NRP2) is a type I transmembrane protein that binds to distinct members of the class III secreted Semaphorin subfamily. NRP2 plays important roles…”
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Upregulation of the Voltage-Gated Sodium Channel beta 2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Assessment of the Leeds Spectral Vision system for detecting biological stains on fabrics by Karchewski, Laurie, Armstrong, Gail, Nicholson, Mary Lou, Wilkinson, Della

“…This study is a comparison of the performance of the Leeds Spectral Vision system (infrared and 455 nm) with the Polilight-Flare ® Plus UV (365 nm) and the…”
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Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury by Befort, Katia, Karchewski, Laurie, Lanoue, Christopher, Woolf, Clifford J.

“…The growth arrest and DNA damage‐inducible gene 45 alpha (Gadd45a) was one of 240 genes found previously by high density oligonucleotide microarray analysis to…”
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Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

“…The development of abnormal primary sensory neuron excitability and neuropathic pain symptoms after peripheral nerve injury is associated with altered…”
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Upregulation of the Voltage-Gated Sodium Channel {beta}2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons by Pertin, Marie, Ji, Ru-Rong, Berta, Temugin, Powell, Andrew J, Karchewski, Laurie, Tate, Simon N, Isom, Lori L, Woolf, Clifford J, Gilliard, Nicolas, Spahn, Donat R, Decosterd, Isabelle

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