Case report: Diffuse large B-cell lymphoma presenting as congestive heart failure in a cat

Cardiac lymphoma is uncommon in cats and is rarely considered as a differential diagnosis for congestive heart failure. A 10-year-old neutered male domestic short-haired cat with clinical histories of feline immunodeficiency virus, diabetes mellitus, and congestive heart failure was humanely euthani...

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Bibliographic Details
Published in:	Frontiers in veterinary science Vol. 11; p. 1467448
Main Authors:	Johnson, Jake, Melhorn, Hannah, Karchemskiy, Sonya, Karlin, Emily, Bain, Perry, Rush, John, Peterson, Cornelia
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 25-09-2024
Subjects:	cardiac neoplasia diffuse large B-cell lymphoma feline feline immunodeficiency virus immunohistochemistry Veterinary Science cardiac neoplasia feline diffuse large B-cell lymphoma immunohistochemistry feline immunodeficiency virus
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Summary:	Cardiac lymphoma is uncommon in cats and is rarely considered as a differential diagnosis for congestive heart failure. A 10-year-old neutered male domestic short-haired cat with clinical histories of feline immunodeficiency virus, diabetes mellitus, and congestive heart failure was humanely euthanized. Post-mortem evaluation demonstrated a massively infiltrative round cell neoplasm of the heart, resulting in CHF. Immunohistochemistry of neoplastic tissue was consistent with diffuse large B-cell lymphoma. This case demonstrates a peculiar presentation of cardiac diffuse large B-cell lymphoma, with chronic feline lentiviral infection possibly contributing to disease initiation and progression.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 Edited by: Francisco Javier Salguero, UK Health Security Agency (UKHSA), United Kingdom Antonella Rigillo, I-Vet srl, Italy Reviewed by: Sara Connolly, University of Illinois at Urbana-Champaign, United States
ISSN:	2297-1769 2297-1769
DOI:	10.3389/fvets.2024.1467448