Search Results - "Karbownik, Małgorzata"
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Molecular analysis of the RET and NTRK1 gene rearrangements in papillary thyroid carcinoma in the Polish population
Published in Mutation research (25-07-2006)“…Among different genetic factors involved in the pathogenesis of the papillary thyroid carcinoma (PTC), rearrangements of RET protooncogene (RET/PTC), as well…”
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Melatonin and Indole-3-Propionic Acid Reduce Oxidative Damage to Membrane Lipids Induced by High Iron Concentrations in Porcine Skin
Published in Membranes (Basel) (29-07-2021)“…Iron excess in tissues results in increased oxidative damage. Among different tissues, the skin can particularly be severely damaged by oxidative stress, as it…”
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17β-Estradiol Stimulates Oxidative Stress Components and Thyroid Specific Genes in Porcine Thyroid Follicular Cells: Potential Differences Between Sexes
Published in Cells (Basel, Switzerland) (01-11-2024)“…17β-estradiol plays a crucial role in regulating cellular processes in both reproductive and non-reproductive tissues, including the thyroid gland. It…”
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Contribution of Ghrelin to the Pathogenesis of Growth Hormone Deficiency
Published in International journal of molecular sciences (23-08-2021)“…In this review we described the interactions between ghrelin and the growth hormone (GH)-insulin-like growth factor 1 (IGF-1) axis in children and adults with…”
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Indole-3-Butyric Acid, a Natural Auxin, Protects against Fenton Reaction-Induced Oxidative Damage in Porcine Thyroid
Published in Nutrients (06-09-2024)“…We present results on the potential protective antioxidant properties of indole-3-butyric acid. Indole-3-butyric acid is an indole derivative defined as an…”
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Determination of glucose cut-off points for optimal performance of glucagon stimulation test
Published in Frontiers in endocrinology (Lausanne) (28-08-2024)“…The glucagon stimulation test (GST) is widely used to assess growth hormone (GH) and cortisol secretion, nevertheless the precise mechanisms underpinning these…”
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Decreased mannan-binding lectin level in adults with hypopituitarism; dependence on appropriate hormone replacement therapies
Published in Frontiers in immunology (12-04-2023)“…Mannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Although there are some studies showing links between endocrine…”
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Sorafenib versus Lenvatinib Causes Stronger Oxidative Damage to Membrane Lipids in Noncancerous Tissues of the Thyroid, Liver, and Kidney: Effective Protection by Melatonin and Indole-3-Propionic Acid
Published in Biomedicines (01-11-2022)“…Sorafenib and lenvatinib are multi-targeted tyrosine kinase inhibitors which are currently approved to treat advanced hepatocellular carcinoma, renal cell…”
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Exogenous Melatonin Protects against Oxidative Damage to Membrane Lipids Caused by Some Sodium/Iodide Symporter Inhibitors in the Thyroid
Published in Antioxidants (29-08-2023)“…The thyroid gland is the primary site of sodium/iodide symporter (NIS), an intrinsic plasma membrane protein responsible for the active uptake of iodine, which…”
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Percentage of Myeloid Dendritic Cells in Peripheral Venous Blood Is Negatively Related to Incidence of Graves’ Orbitopathy
Published in Mediators of inflammation (2021)“…The aim of the study was to evaluate the distribution of blood dendritic cells (DCs) in patients with Graves’ orbitopathy (GO) and to assess the influence of…”
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The Protective Effect of Exogenous 17β-Estradiol against Experimentally Induced Oxidative Damage to Membrane Lipids Is Stronger in Male vs. Female Porcine Thyroids: Preliminary Results
Published in Toxics (Basel) (01-09-2023)“…It is well-known that thyroid diseases are more prevalent in women than in men. The contribution of sex hormones may explain such disparity. The aim of this…”
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Oxidative damage to macromolecules in the thyroid - experimental evidence
Published in Thyroid research (27-12-2012)“…Whereas oxidative reactions occur in all tissues and organs, the thyroid gland constitutes such an organ, in which oxidative processes are indispensable for…”
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Single-nucleotide polymorphisms and mRNA expression for melatonin synthesis rate-limiting enzyme in recurrent depressive disorder
Published in Journal of pineal research (01-05-2010)“…: Depressive disorder (DD) is characterised by disturbances in blood melatonin concentration. It is well known that melatonin is involved in the control of…”
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The thyroid gland and the process of aging; what is new?
Published in Thyroid research (01-01-2012)“…The endocrine system and particular endocrine organs, including the thyroid, undergo important functional changes during aging. The prevalence of thyroid…”
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Single nucleotide polymorphisms and mRNA expression for melatonin MT2 receptor in depression
Published in Psychiatry research (30-10-2011)“…Abstract Polymorphisms (rs 4753426 and rs 794837) and expression of the melatonin MT2 receptor gene were evaluated in 181 patients with recurrent depressive…”
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Can thyroid size still be considered as a useful tool for assessing iodine intake?
Published in Annals of Agricultural and Environmental Medicine (01-01-2015)“…It has always been very difficult to precisely define a goitre. For years, the borderline values have been sought which could be universally used in such…”
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Melatonin reduces fenton reaction-induced lipid peroxidation in porcine thyroid tissue
Published in Journal of cellular biochemistry (01-11-2003)“…Free radicals and reactive oxygen species (ROS) participate in physiological and pathological processes in the thyroid gland. Bivalent iron cation (ferrous,…”
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Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates
Published in Frontiers in molecular biosciences (03-06-2022)“…Iron is an essential microelement for the proper functioning of many organs, among others it is required for thyroid hormone synthesis. However, its overload…”
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Protective effects of melatonin and indole-3-propionic acid against lipid peroxidation, caused by potassium bromate in the rat kidney
Published in Cell biochemistry and function (01-11-2006)“…Potassium bromate (KBrO3) is classified as a carcinogenic agent. KBrO3 induces tumors and prooxidative effects in kidneys. Melatonin is a well known…”
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Co-existence of chronic non-communicable diseases and common neoplasms among 2,462 endocrine adult inpatients - a retrospective analysis
Published in Annals of Agricultural and Environmental Medicine (01-01-2015)“…To analyze the coexistence of chronic non-communicable diseases (NCDs) and common neoplasms among endocrine adult inpatients. The retrospective analysis was…”
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