Search Results - "Karbon, E. William"

[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes by Karbon, E W, Naper, K, Pontecorvo, M J

“…The interaction of various compounds with sigma binding sites was examined in membranes prepared from whole guinea pig brain. Whereas…”
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Ifenprodil potently interacts with [3H](+)-3-PPP-labeled sigma binding sites in guinea pig brain membranes by Karbon, E W, Patch, R J, Pontecorvo, M J, Ferkany, J W

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Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents by Pontecorvo, M J, Karbon, E W, Goode, S, Clissold, D B, Borosky, S A, Patch, R J, Ferkany, J W

“…The recent finding that ifenprodil binds with high affinity to sigma sites suggests that other sigma agents may have ifenprodil-like cerebroprotectant and…”
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Bridged .gamma.-carbolines and derivatives possessing selective and combined affinity for 5-HT2 and D2 receptors by Mewshaw, Richard E, Silverman, Lisa S, Mathew, Rose M, Kaiser, Carl, Sherrill, Ronald G, Cheng, Menyan, Tiffany, Carol W, Karbon, E. William, Bailey, Michael A

“…A series of 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles and 6,7,8,9,10,11-hexahydro-7,11-imino-5H-cyclooct[b]indoles was prepared. Structural…”
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Haloperidol treatment differentially regulates [3H]DTG and [3H](+)-3-PPP labeled sigma binding sites by Bailey, M A, Karbon, E W

“…The effect of repeated haloperidol administration on sigma binding sites in brain membranes was assessed using [3H](+)-3-(3-hydroxyphenyl)-N-(1-…”
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Synthesis and in vitro evaluation of 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles: high-affinity ligands for the N,N'-di-o-tolylguanidine-labeled .sigma. binding site by Mewshaw, Richard E, Sherrill, Ronald G, Mathew, Rose M, Kaiser, Carl, Bailey, Michael A, Karbon, E. William

“…A series of 5,6,7,8,9,10-hexahydro-7,10-iminocyclo[b]indoles substituted at the 5 and/or 11 positions was synthesized from tropinone. Affinity for sigma…”
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Opposite effects of spermine and arcaine on responses of N-methyl-D-aspartate receptors expressed in Xenopus oocytes by Maciver, C R, Bednar, D L, Karbon, E W

“…The ability of polyamines to modulate N-methyl-D-aspartate (NMDA) receptor function was investigated in Xenopus oocytes injected with rat brain mRNA. Whereas…”
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The envelope glycoprotein of HIV-1 alters NMDA receptor function by Sweetnam, P M, Saab, O H, Wroblewski, J T, Price, C H, Karbon, E W, Ferkany, J W

“…Human immunodeficiency virus (HIV-1) infection often results in central nervous system (CNS) dysfunction, yet the mechanism(s) of action for HIV-1 in the CNS…”
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Examination of the D2/5-HT2 affinity ratios of resolved 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles: an enantioselective approach toward the design of potential atypical antipsychotics by Mewshaw, Richard E, Abreu, Mary E, Silverman, Lisa S, Mathew, Rose M, Tiffany, Carol W, Bailey, Michael A, Karbon, E. William, Ferkany, John W, Kaiser, Carl

“…Enantiomers of several N-substituted 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles were obtained by the resolution of…”
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gamma-Aminobutyric acidB receptor activation modifies agonist binding to beta-adrenergic receptors in rat brain cerebral cortex by Scherer, R W, Ferkany, J W, Karbon, E W, Enna, S J

“…The interaction of isoproterenol with beta-adrenergic receptor (beta AR) binding sites was measured in membranes prepared from rat brain cerebral cortical…”
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Biochemical identification of multiple GABAB binding sites: association with noradrenergic terminals in rat forebrain by Karbon, E W, Duman, R, Enna, S J

“…GABAA (bicuculline-sensitive) and GABAB (bicuculline-insensitive) receptor binding were examined in an attempt to determine whether either site was present on…”
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Augmentation of neurotransmitter receptor-stimulated cyclic AMP accumulation in rat brain: differentiation between the effects of baclofen and phorbol esters by Scherer, R W, Karbon, E W, Ferkany, J W, Enna, S J

“…The augmentation of isoproterenol or vasoactive intestinal peptide (VIP)-stimulated cyclic AMP accumulation in rat brain slices by the GABAB agonist baclofen…”
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