Search Results - "Karbach, H."

Lysozyme M―Positive Monocytes Mediate Angiotensin II―Induced Arterial Hypertension and Vascular Dysfunction by WENZEL, Philip, KNORR, Maike, OELZE, Matthias, GRABBE, Stephan, JONULEIT, Helmut, BECKER, Christian, DAIBER, Andreas, WAISMAN, Ari, MÜNZEL, Thomas, KOSSMANN, Sabine, STRATMANN, Jan, HAUSDING, Michael, SCHUHMACHER, Swenja, KARBACH, Susanne H, SCHWENK, Melanie, YOGEV, Nir, SCHULZ, Eberhard

“…Angiotensin II (ATII), a potent vasoconstrictor, causes hypertension, promotes infiltration of myelomonocytic cells into the vessel wall, and stimulates both…”
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Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction by Karbach, Susanne H., Schönfelder, Tanja, Brandão, Ines, Wilms, Eivor, Hörmann, Nives, Jäckel, Sven, Schüler, Rebecca, Finger, Stefanie, Knorr, Maike, Lagrange, Jeremy, Brandt, Moritz, Waisman, Ari, Kossmann, Sabine, Schäfer, Katrin, Münzel, Thomas, Reinhardt, Christoph, Wenzel, Philip

“…Background The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure…”
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Inflammatory Monocytes Determine Endothelial Nitric-oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II by Kossmann, Sabine, Hu, Hanhan, Steven, Sebastian, Schönfelder, Tanja, Fraccarollo, Daniela, Mikhed, Yuliya, Brähler, Melanie, Knorr, Maike, Brandt, Moritz, Karbach, Susanne H., Becker, Christian, Oelze, Matthias, Bauersachs, Johann, Widder, Julian, Münzel, Thomas, Daiber, Andreas, Wenzel, Philip

“…Endothelial nitric-oxide synthase (eNOS) uncoupling and increased inducible NOS (iNOS) activity amplify vascular oxidative stress. The role of inflammatory…”
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An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling by El Malki, Khalifa, Karbach, Susanne H., Huppert, Jula, Zayoud, Morad, Reißig, Sonja, Schüler, Rebecca, Nikolaev, Alexej, Karram, Khalad, Münzel, Thomas, Kuhlmann, Christoph R.W., Luhmann, Heiko J., von Stebut, Esther, Wörtge, Simone, Kurschus, Florian C., Waisman, Ari

“…Topical application of imiquimod (IMQ) on the skin of mice induces inflammation with common features found in psoriatic skin. Recently, it was postulated that…”
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Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension by Kossmann, Sabine, Lagrange, Jeremy, Jäckel, Sven, Jurk, Kerstin, Ehlken, Moritz, Schönfelder, Tanja, Weihert, Yvonne, Knorr, Maike, Brandt, Moritz, Xia, Ning, Li, Huige, Daiber, Andreas, Oelze, Matthias, Reinhardt, Christoph, Lackner, Karl, Gruber, Andras, Monia, Brett, Karbach, Susanne H, Walter, Ulrich, Ruggeri, Zaverio M, Renné, Thomas, Ruf, Wolfram, Münzel, Thomas, Wenzel, Philip

“…Multicellular interactions of platelets, leukocytes, and the blood vessel wall support coagulation and precipitate arterial and venous thrombosis. High levels…”
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Correlation of cardiac function and cerebral perfusion in a murine model of subarachnoid hemorrhage by Neulen, Axel, Molitor, Michael, Kosterhon, Michael, Pantel, Tobias, Holzbach, Elisa, Rudi, Wolf-Stephan, Karbach, Susanne H., Wenzel, Philip, Ringel, Florian, Thal, Serge C.

“…Cerebral hypoperfusion is a key factor for determining the outcome after subarachnoid hemorrhage (SAH). A subset of SAH patients develop neurogenic stress…”
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Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation by Schütz, Eva, Gogiraju, Rajinikanth, Pavlaki, Maria, Drosos, Ioannis, Georgiadis, George S, Argyriou, Christos, Rim Ben Hallou, Amina, Konstantinou, Fotios, Mikroulis, Dimitrios, Schüler, Rebecca, Bochenek, Magdalena L, Gachkar, Sogol, Buschmann, Katja, Lankeit, Mareike, Karbach, Susanne H, Münzel, Thomas, Tziakas, Dimitrios, Konstantinides, Stavros, Schäfer, Katrin

“…Cardiovascular risk factors may act by modulating the composition and function of the adventitia. Here we examine how age affects perivascular adipose tissue…”
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IL-6 Signaling in Myelomonocytic Cells Is Not Crucial for the Development of IMQ-Induced Psoriasis by Klebow, Sabrina, Hahn, Matthias, Nikoalev, Alexei, Wunderlich, F Thomas, Hövelmeyer, Nadine, Karbach, Susanne H, Waisman, Ari

“…Psoriasis is an autoimmune skin disease that is associated with aberrant activity of immune cells and keratinocytes. In mice, topical application of TLR7/8…”
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ACE Inhibition Modulates Myeloid Hematopoiesis after Acute Myocardial Infarction and Reduces Cardiac and Vascular Inflammation in Ischemic Heart Failure by Rudi, Wolf-Stephan, Molitor, Michael, Garlapati, Venkata, Finger, Stefanie, Wild, Johannes, Münzel, Thomas, Karbach, Susanne H, Wenzel, Philip

“…Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a cornerstone of drug therapy after myocardial infarction (MI) and improve left ventricular…”
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RELAPSE OF ACUTE LYMPHOBLASTIC LEUKAEMIA IN OLDER/ELDERLY PATIENTS: A SWEDISH POPULATION-BASED STUDY by Bergfelt, E., Kozlowski, Piotr, Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Åström, Maria, Hallböök, H.

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Prognosis in older/elderly patients with acute lymphoblastic leukaemia diagnosed 2005-2012: results from a Swedish population-based study by Bergfelt, E., Kozlowski, Piotr, Åström, Maria, Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Hallböök, H.

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Nox2+ myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1 by Molitor, Michael, Rudi, Wolf-Stephan, Garlapati, Venkata, Finger, Stefanie, Schüler, Rebecca, Kossmann, Sabine, Lagrange, Jeremy, Nguyen, Thanh Son, Wild, Johannes, Knopp, Tanja, Karbach, Susanne H, Knorr, Maike, Ruf, Wolfram, Münzel, Thomas, Wenzel, Philip

“…Heart failure (HF) ensuing myocardial infarction (MI) is characterized by the initiation of a systemic inflammatory response. We aimed to elucidate the impact…”
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Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis by Schönfelder, Tanja, Brandt, Moritz, Kossmann, Sabine, Knopp, Tanja, Münzel, Thomas, Walter, Ulrich, Karbach, Susanne H., Wenzel, Philip

“…The role of leukocytes in deep vein thrombosis (DVT) resolution is incompletely understood. We determined how depletion of lysozyme positive (LysM + ) cells…”
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Angiotensin II-induced vascular dysfunction depends on interferon-γ-driven immune cell recruitment and mutual activation of monocytes and NK-cells by Kossmann, Sabine, Schwenk, Melanie, Hausding, Michael, Karbach, Susanne H, Schmidgen, Maria I, Brandt, Moritz, Knorr, Maike, Hu, Hanhan, Kröller-Schön, Swenja, Schönfelder, Tanja, Grabbe, Stephan, Oelze, Matthias, Daiber, Andreas, Münzel, Thomas, Becker, Christian, Wenzel, Philip

“…Immune cells contribute to angiotensin II (ATII)-induced vascular dysfunction and inflammation. Interferon-γ (IFN-γ), an inflammatory cytokine exclusively…”
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Outcome after HSCT in Philadelphia chromosome positive acute lymphoblastic leukemia in Sweden: a population-based study by Hulegårdh, E., Hägglund, H., Ahlberg, L., Karlsson, K., Karbach, H., Markuszewska, A., Persson, I., Åström, M., Hallböök, H.

“…Even in the tyrosine kinase inhibitor era, allogeneic hematopoietic stem cell transplantation (HSCT) is regarded as standard care for adult Philadelphia (Ph)…”
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Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans by Wenzel, Philip, Rossmann, Heidi, Müller, Christian, Kossmann, Sabine, Oelze, Matthias, Schulz, Andreas, Arnold, Natalie, Simsek, Canan, Lagrange, Jeremy, Klemz, Roman, Schönfelder, Tanja, Brandt, Moritz, Karbach, Susanne H., Knorr, Maike, Finger, Stefanie, Neukirch, Carolin, Häuser, Friederike, Beutel, Manfred E., Kröller-Schön, Swenja, Schulz, Eberhard, Schnabel, Renate B., Lackner, Karl, Wild, Philipp S., Zeller, Tanja, Daiber, Andreas, Blankenberg, Stefan, Münzel, Thomas

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Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans by Wenzel, Philip, Rossmann, Heidi, Müller, Christian, Kossmann, Sabine, Oelze, Matthias, Schulz, Andreas, Arnold, Natalie, Simsek, Canan, Lagrange, Jeremy, Klemz, Roman, Schönfelder, Tanja, Brandt, Moritz, Karbach, Susanne H, Knorr, Maike, Finger, Stefanie, Neukirch, Carolin, Häuser, Friederike, Beutel, Manfred E, Kröller-Schön, Swenja, Schulz, Eberhard, Schnabel, Renate B, Lackner, Karl, Wild, Philipp S, Zeller, Tanja, Daiber, Andreas, Blankenberg, Stefan, Münzel, Thomas

“…Heme oxygenase-1 (HO-1) confers protection to the vasculature and suppresses inflammatory properties of monocytes and macrophages. It is unclear how HO-1…”
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Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression by Mufazalov, Ilgiz A, Andruszewski, David, Schelmbauer, Carsten, Heink, Sylvia, Blanfeld, Michaela, Masri, Joumana, Tang, Yilang, Schüler, Rebecca, Eich, Christina, Wunderlich, F Thomas, Karbach, Susanne H, Bluestone, Jeffrey A, Korn, Thomas, Waisman, Ari

“…IL-6 binds to the IL-6R α-chain (IL-6Rα) and signals via the signal transducer gp130. Recently, IL-6 was found to also bind to the cell surface glycoprotein…”
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Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation by Veras, Flávio P., Publio, Gabriel A., Melo, Bruno M., Prado, Douglas S., Norbiato, Thainá, Cecilio, Nerry T., Hiroki, Carlos, Damasceno, Luis Eduardo A., Jung, Rebecca, Toller-Kawahisa, Juliana E., Martins, Timna V., Assunção, Stella F., Lima, Diogenes, Alves, Marcia G., Vieira, Gabriel V., Tavares, Lucas A., Alves-Rezende, Ana L.R., Karbach, Susanne H., Nakaya, Helder I., Cunha, Thiago M., Souza, Cacilda S., Cunha, Fernando Q., Sales, Katiuchia U., Waisman, Ari, Alves-Filho, José C.

“…Psoriasis is an inflammatory skin disease characterized by keratinocyte proliferation and inflammatory cell infiltration induced by IL-17. However, the…”
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Retrieval of aerosol properties from boundary layer extinction measurements with a DOAS System by Flentje, H., Dubois, R., Heintzenberg, J., Karbach, H.-J.

“…Boundary layer trace gas and particulate extinction measurements in the wavelength region from 320 nm to 680 nm have been performed by means of a differential…”
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