Search Results - "Karathanasi, Afroditi"

Veliparib in ovarian cancer: a new synthetically lethal therapeutic approach by Boussios, Stergios, Karihtala, Peeter, Moschetta, Michele, Abson, Charlotte, Karathanasi, Afroditi, Zakynthinakis-Kyriakou, Nikolaos, Ryan, Jake Edward, Sheriff, Matin, Rassy, Elie, Pavlidis, Nicholas

“…Summary Epithelial ovarian cancer (EOC) accounts for nearly 90% of all ovarian malignancies. The standard therapeutic strategy includes cytoreductive surgery…”
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Poly (ADP-Ribose) Polymerase Inhibitors: Talazoparib in Ovarian Cancer and Beyond by Boussios, Stergios, Abson, Charlotte, Moschetta, Michele, Rassy, Elie, Karathanasi, Afroditi, Bhat, Tahir, Ghumman, Faisal, Sheriff, Matin, Pavlidis, Nicholas

“…Genetic complexity and DNA damage repair defects are common in different cancer types and can induce tumor-specific vulnerabilities. Poly(ADP-ribose)…”
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Combined Strategies with Poly (ADP-Ribose) Polymerase (PARP) Inhibitors for the Treatment of Ovarian Cancer: A Literature Review by Boussios, Stergios, Karihtala, Peeter, Moschetta, Michele, Karathanasi, Afroditi, Sadauskaite, Agne, Rassy, Elie, Pavlidis, Nicholas

“…Poly (ADP-ribose) polymerase (PARP) inhibitors are the first clinically approved drugs designed to exploit synthetic lethality, and were first introduced as a…”
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The Developing Story of Predictive Biomarkers in Colorectal Cancer by Boussios, Stergios, Ozturk, Mehmet Akif, Moschetta, Michele, Karathanasi, Afroditi, Zakynthinakis-Kyriakou, Nikolaos, Katsanos, Konstantinos H, Christodoulou, Dimitrios K, Pavlidis, Nicholas

“…Colorectal cancer (CRC) is the third most common malignancy worldwide. Surgery remains the most important treatment for non-metastatic CRC, and the…”
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Wise Management of Ovarian Cancer: On the Cutting Edge by Boussios, Stergios, Mikropoulos, Christos, Samartzis, Eleftherios, Karihtala, Peeter, Moschetta, Michele, Sheriff, Matin, Karathanasi, Afroditi, Sadauskaite, Agne, Rassy, Elie, Pavlidis, Nicholas

“…Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality among women. Two-thirds of patients present at advanced stage at diagnosis, and…”
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Cancer-Associated Thrombosis: A New Light on an Old Story by Shah, Sidrah, Karathanasi, Afroditi, Revythis, Antonios, Ioannidou, Evangelia, Boussios, Stergios

“…Cancer-associated thrombosis (CAT) is a rising and significant phenomenon, becoming the second leading cause of death in cancer patients. Pathophysiology of…”
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PARP Inhibitors in Ovarian Cancer: The Route to "Ithaca" by Boussios, Stergios, Karathanasi, Afroditi, Cooke, Deirdre, Neille, Cherie, Sadauskaite, Agne, Moschetta, Michele, Zakynthinakis-Kyriakou, Nikolaos, Pavlidis, Nicholas

“…Poly (ADP-ribose) polymerase (PARP) inhibitors are a novel class of therapeutic agents that target tumors with deficiencies in the homologous recombination DNA…”
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Ovarian carcinosarcoma: Current developments and future perspectives by Boussios, Stergios, Karathanasi, Afroditi, Zakynthinakis-Kyriakou, Nikolaos, Tsiouris, Alexandros K., Chatziantoniou, Aikaterini A., Kanellos, Foivos S., Tatsi, Konstantina

“…[Display omitted] Ovarian carcinosarcoma (OCS) constitute uncommon malignancies accounting for only 1–4% of ovarian cancers. Patients more often present with…”
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Metastatic Spinal Cord Compression: Unraveling the Diagnostic and Therapeutic Challenges by Boussios, Stergios, Cooke, Deirdre, Hayward, Catherine, Kanellos, Foivos S, Tsiouris, Alexandros K, Chatziantoniou, Aikaterini A, Zakynthinakis-Kyriakou, Nikolaos, Karathanasi, Afroditi

“…Malignant spinal cord compression (MSCC) is one of the most devastating complications of cancer. Patients often present with a history of progressive pain,…”
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The Experience of a Single NHS England Trust on the Impact of the COVID-19 Pandemic on Junior and Middle-Grade Doctors: What Is Next? by Revythis, Antonios, Shah, Sidrah, Enyioma, Synthia, Ghose, Aruni, Patel, Meenash, Karathanasi, Afroditi, Sanchez, Elisabet, Boussios, Stergios

“…The COVID-19 pandemic has undoubtedly affected all national healthcare systems at different levels. In countries heavily hit by the pandemic, it was reported…”
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Prognostic Factors in Patients with Metastatic Spinal Cord Compression Secondary to Lung Cancer—A Retrospective UK Single-Centre Study by Vassiliou, Anna, Osunronbi, Temidayo, Enyioma, Synthia, Rago, Gerardo, Karathanasi, Afroditi, Ghose, Aruni, Sheriff, Matin, Mikropoulos, Christos, Sanchez, Elisabet, Moschetta, Michele, Chargari, Cyrus, Rassy, Elie, Boussios, Stergios

“…Purpose: Metastatic spinal cord compression (MSCC) is a severe complication of cancer that can lead to irreversible neurological impairment, necessitating…”
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Spinal Ewing Sarcoma Debuting with Cord Compression: Have We Discovered the Thread of Ariadne? by Boussios, Stergios, Hayward, Catherine, Cooke, Deirdre, Zakynthinakis-Kyriakou, Nikolaos, Tsiouris, Alexandros K, Chatziantoniou, Aikaterini A, Kanellos, Foivos S, Karathanasi, Afroditi

“…Ewing's sarcoma (ES) of the spine with cord or radicular compression as an initial sign is infrequent. It is unclear, in alleviating a neurological deficit,…”
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Malignant peritoneal mesothelioma: clinical aspects, and therapeutic perspectives by Boussios, Stergios, Moschetta, Michele, Karathanasi, Afroditi, Tsiouris, Alexandros K, Kanellos, Foivos S, Tatsi, Konstantina, Katsanos, Konstantinos H, Christodoulou, Dimitrios K

“…Malignant peritoneal mesothelioma (MPM) is a rare disease with a wide clinical spectrum. It arises from the peritoneal lining and commonly presents with…”
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Management of Metastatic Spinal Cord Compression in Secondary Care: A Practice Reflection from Medway Maritime Hospital, Kent, UK by Shah, Sidrah, Kutka, Mikolaj, Lees, Kathryn, Abson, Charlotte, Hadaki, Maher, Cooke, Deirdre, Neill, Cherie, Sheriff, Matin, Karathanasi, Afroditi, Boussios, Stergios

“…Malignant spinal cord compression (MSCC) is one of the most devastating complications of cancer. This event requires rapid decision-making on the part of…”
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Development of new poly(ADP-ribose) polymerase (PARP) inhibitors in ovarian cancer: Quo Vadis? by Boussios, Stergios, Moschetta, Michele, Karihtala, Peeter, Samartzis, Eleftherios P, Sheriff, Matin, Pappas-Gogos, George, Ozturk, Mehmet Akif, Uccello, Mario, Karathanasi, Afroditi, Tringos, Michail, Rassy, Elie, Pavlidis, Nicholas

“…Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality among women, potentially due to ineffectiveness of screening tests for early…”
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Langerhans cell histiocytosis with spinal, pulmonary and pituitary involvement: What about ACTH deficiency without diabetes insipidus? A propos of a case by E Ryan, Jake, Ganesh, Vijayakumar, Karathanasi, Afroditi, Moschetta, Michele, Sheriff, Matin, B Schofield, John, Boussios, Stergios

“…Langerhans cell histiocytosis (LCH) is disease process characterized by clonal proliferation of CD1a+ dendritic cells within an inflammatory infiltrate of…”
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