Search Results - "Karasawa, Kaoru"
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1
Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model
Published in Journal of investigative dermatology (01-01-2016)“…Elevated skin surface pH has been reported in patients with atopic dermatitis. In this study, we explored the role of skin pH in the pathogenesis of atopic…”
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2
Mast cell hyperactivity underpins the development of oxygen-induced retinopathy
Published in The Journal of clinical investigation (01-11-2017)“…Mast cells are classically thought to play an important role in protection against helminth infections and in the induction of allergic diseases; however,…”
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3
Changes in serum NGF levels after the exercise load in dogs: a pilot study
Published in Journal of Veterinary Medical Science (2016)“…Serum nerve growth factor (NGF) levels are increased by the external stress in mice, humans and horses; however, similar variations have been unclear in dogs…”
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4
Evaluation of stress status using the stress map for guide dog candidates in the training stage using variations in the serum cortisol with nerve growth factor and magnesium ions
Published in Veterinary and animal science (01-12-2020)“…•Serum cortisol, NGF, and Mg2+ levels of the guide dog candidates were evaluated in each stage of their training.•Serum cortisol levels were sensitive to the…”
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5
Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control
Published in BMC research notes (29-10-2018)“…Clinical research on gene therapy has advanced the field of veterinary medicine, and gene doping, which is the illegal use of gene therapy, has become a major…”
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6
Peroxisome proliferator–activated receptor γ–mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice
Published in Journal of allergy and clinical immunology (01-02-2011)“…Background Dendritic cells (DCs) are one of the key regulators for the initiation of allergic responses in patients with atopic dermatitis (AD), being strongly…”
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7
Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease
Published in Cardiovascular research (01-11-2011)“…Intermittent claudication (IC) is one of the serious symptoms of peripheral arterial disease (PAD) and is characterized by pain in the legs or buttocks that…”
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8
Analysis of serum magnesium ions in dogs exposed to external stress: A pilot study
Published in Open veterinary journal (Tripoli, Libya) (01-01-2017)“…Magnesium ions (Mg 2+ ) are essential for various enzymatic reactions in the body associated with energy production and activation of the muscles and nerves…”
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9
Glucocorticoid sensitivity depends on expression levels of glucocorticoid receptors in canine neoplastic mast cells
Published in Veterinary immunology and immunopathology (15-12-2011)“…Glucocorticoid (GC) administration with or without other chemotherapeutic reagents is a commonly used option in the treatment of mast cell malignancies…”
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10
Fast Electron Detachment Dissociation of Oligonucleotides in Electron-Nitrogen Plasma Stored in Magneto Radio-Frequency Ion Traps
Published in Analytical chemistry (Washington) (08-11-2022)“…We report “plasma” electron detachment dissociation (EDD), a novel electron-activated dissociation (EAD) method for the fast sequencing of oligonucleotides…”
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11
Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry
Published in Analytical chemistry (Washington) (07-11-2023)“…We report the first sequencing of morpholino antisense oligonucleotides (phosphorodiamidate morpholino oligomers, PMOs) using electron capture dissociation…”
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12
Changes in serum NGF levels after the exercise load in dogs
Published in Journal of veterinary medical science (01-11-2016)“…Serum nerve growth factor (NGF) levels are increased by the external stress in mice, humans and horses; however, similar variations have been unclear in dogs…”
Get full text
Journal Article -
13
Patterns of aquaporin expression in the canine eye
Published in The veterinary journal (1997) (01-11-2011)“…Aquaporins (AQPs) function as water channels in many types of cells involved in fluid transport. More than 10 isoforms have been identified, and these are…”
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14
Mast cell hyperactivity underpins the development of oxygen-induced retinopathy
Published in The Journal of clinical investigation (01-11-2017)“…Mast cells are classically thought to play an important role in protection against helminth infections and in the induction of allergic diseases; however,…”
Get full text
Journal Article -
15
Characterization of geometrid sex pheromones by electrospray ionization time-of-flight mass spectrometry
Published in Journal of mass spectrometry. (01-03-2003)“…The utility of liquid chromatography combined with time‐of‐flight mass spectrometry (LC/TOFMS) was demonstrated for studies on chiral unsaturated epoxy…”
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16
Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease
Published in Cardiovascular research (01-11-2011)“…Aims Intermittent claudication (IC) is one of the serious symptoms of peripheral arterial disease (PAD) and is characterized by pain in the legs or buttocks…”
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Journal Article -
17
Development of a novel carrier optimized for cell sheet transplantation
Published in Biomatter (Austin, TX) (2015)“…Tissue engineering is a rapidly advancing technology in the field of regenerative medicine. For the transplantation of cell sheets, a carrier must maintain the…”
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18
Peroxisome proliferator-activated receptor [gamma]-mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice
Published in Journal of allergy and clinical immunology (01-02-2011)“…Background Dendritic cells (DCs) are one of the key regulators for the initiation of allergic responses in patients with atopic dermatitis (AD), being strongly…”
Get full text
Journal Article -
19
Retinal Degeneration and rd1 Mutation in NC/Tnd Mice-A Human Atopic Dermatitis Model
Published in Current eye research (01-04-2011)“…Purpose: NC/Tnd mice, a spontaneous model for human atopic dermatitis, are also useful animal models for various corneal disorders accompanying allergic…”
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20
Skin pH is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model
Published in Journal of investigative dermatology (22-09-2015)“…Elevated skin surface pH has been reported in patients with atopic dermatitis (AD). Here we explored the role of skin pH in the pathogenesis of AD using the…”
Get full text
Journal Article