Search Results - "Karaolis, David K.R"

c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection by Ogunniyi, Abiodun D, Paton, James C, Kirby, Alun C, McCullers, Jonathan A, Cook, Jan, Hyodo, Mamoru, Hayakawa, Yoshihiro, Karaolis, David K.R

“…Abstract Cyclic diguanylate (c-di-GMP) is a unique bacterial intracellular signaling molecule capable of stimulating enhanced protective innate immunity…”
Get full text

c-di-GMP as a vaccine adjuvant enhances protection against systemic methicillin-resistant Staphylococcus aureus (MRSA) infection by Hu, Dong-Liang, Narita, Kouji, Hyodo, Mamoru, Hayakawa, Yoshihiro, Nakane, Akio, Karaolis, David K.R

“…Abstract Cyclic diguanylate (c-di-GMP) is a novel immunomodulator and immune enhancer that triggers a protective host innate immune response. The protective…”
Get full text

STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer by Chandra, Dinesh, Quispe-Tintaya, Wilber, Jahangir, Arthee, Asafu-Adjei, Denise, Ramos, Ilyssa, Sintim, Herman O, Zhou, Jie, Hayakawa, Yoshihiro, Karaolis, David K R, Gravekamp, Claudia

“…Cancer vaccination may be our best and most benign option for preventing or treating metastatic cancer. However, breakthroughs are hampered by immune…”
Get more information

Cyclic Di-GMP Stimulates Protective Innate Immunity in Bacterial Pneumonia by Karaolis, David K.R, Newstead, Michael W, Zeng, Xianying, Hyodo, Mamoru, Hayakawa, Yoshihiro, Bhan, Urvhashi, Liang, Hallie, Standiford, Theodore J

“…Innate immunity is the primary mechanism by which extracellular bacterial pathogens are effectively cleared from the lung. We have previously shown that cyclic…”
Get full text

Identification of genes involved in the switch between the smooth and rugose phenotypes of Vibrio cholerae by Rashid, Mohammed H, Rajanna, Chythanya, Ali, Afsar, Karaolis, David K.R

“…Vibrio cholerae can switch to a ‘rugose’ phenotype characterized by an exopolysaccharide (EPS) matrix, wrinkled colony morphology, increased biofilm formation…”
Get full text

Role of exopolysaccharide, the rugose phenotype and VpsR in the pathogenesis of epidemic Vibrio cholerae by Rashid, Mohammed H, Rajanna, Chythanya, Zhang, Dalin, Pasquale, Vincenzo, Magder, Laurence S, Ali, Afsar, Dumontet, Stefano, Karaolis, David K.R

“…Vibrio cholerae, the causative agent of cholera can produce an exopolysaccharide (EPS). Some strains can also phenotypically switch from a smooth to a ‘rugose’…”
Get full text

Prevalence of virulence-associated genes in clinical and environmental Vibrio cholerae strains isolated in Brazil between 1991 and 1999 by Vital Brazil, Juliana M, Alves, Ronaldo M, Rivera, Irma N.G, Rodrigues, Dália P, Karaolis, David K.R, Campos, Leila C

“…Genes located on the CTX element and the Vibrio cholerae pathogenicity island (VPI) were investigated in 297 clinical V. cholerae O1 and 76 environmental O1…”
Get full text

Bacterial c-di-GMP Is an Immunostimulatory Molecule by Karaolis, David K. R, Means, Terry K, Yang, De, Takahashi, Munehisa, Yoshimura, Teizo, Muraille, Eric, Philpott, Dana, Schroeder, John T, Hyodo, Mamoru, Hayakawa, Yoshihiro, Talbot, Brian G, Brouillette, Eric, Malouin, Francois

“…Cyclic diguanylate (c-di-GMP) is a bacterial intracellular signaling molecule. We have shown that treatment with exogenous c-di-GMP inhibits Staphylococcus…”
Get full text

Extraction of Aerosol-Deposited Yersinia pestis from Indoor Surfaces To Determine Bacterial Environmental Decay by Gut, Ian M, Bartlett, Ryan A, Yeager, John J, Leroux, Brian, Ratnesar-Shumate, Shanna, Dabisch, Paul, Karaolis, David K R

“…Public health and decontamination decisions following an event that causes indoor contamination with a biological agent require knowledge of the environmental…”
Get full text

c-di-GMP (3′-5′-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation by KARAOLIS, David K. R, RASHID, Mohammed H, CHYTHANYA, Rajanna, WENSHENG LUO, HYODO, Mamoru, HAYAKAWA, Yoshihiro

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

3′,5′-Cyclic Diguanylic Acid Reduces the Virulence of Biofilm-Forming Staphylococcus aureus Strains in a Mouse Model of Mastitis Infection by BROUILLETTE, Eric, HYODO, Mamoru, HAYAKAWA, Yoshihiro, KARAOLIS, David K. R, MALOUIN, Francois

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

3′,5′-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation by Karaolis, David K.R., Cheng, Kunrong, Lipsky, Michael, Elnabawi, Ahmed, Catalano, Jennifer, Hyodo, Mamoru, Hayakawa, Yoshihiro, Raufman, Jean-Pierre

“…The novel cyclic dinucleotide, 3′,5′-cyclic diguanylic acid, cGpGp (c-di-GMP), is a naturally occurring small molecule that regulates important signaling…”
Get full text

A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria by Karaolis, David K. R, Somara, Sita, Maneval, David R, Johnson, Judith A, Kaper, James B

“…The virulence properties of many pathogenic bacteria are due to proteins encoded by large gene clusters called pathogenicity islands, which are found in a…”
Get full text

A Vibrio cholerae Pathogenicity Island Associated with Epidemic and Pandemic Strains by David K. R. Karaolis, Johnson, Judith A., Bailey, Camella C., Boedeker, Edgar C., Kaper, James B., Reeves, Peter R.

“…The bacterial species Vibrio cholerae includes harmless aquatic strains as well as strains capable of causing epidemics and global pandemics of cholera. While…”
Get full text

Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies by PUPO, G. M, KARAOLIS, D. K. R, LAN, R, REEVES, P. R

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

High-Frequency Rugose Exopolysaccharide Production by Vibrio cholerae by ALI, Afsar, RASHID, Mohammed H, KARAOLIS, David K. R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Corrigendum to “Identification of genes involved in the switch between the smooth and rugose phenotypes of Vibrio cholerae” by Rashid, Mohammed H, Rajanna, Chythanya, Ali, Afsar, Karaolis, David K.R

Get full text

Transcriptional analysis and operon structure of the tagA–orf2–orf3–mop–tagD region on the Vibrio pathogenicity island in epidemic V. cholerae by Zhang, Dalin, Manos, Jim, Ma, Xinrong, Belas, Robert, Karaolis, David K.R.

Get full text

Corrigendum to “Identification of genes involved in the switch between the smooth and rugose phenotypes of Vibrio cholerae” : [FEMS Microbiol. Lett. 227 (2003) 113–119] by Rashid, Mohammed H, Rajanna, Chythanya, Ali, Afsar, Karaolis, David K.R

Get full text

The Vibrio Pathogenicity Island-Encoded Mop Protein Modulates the Pathogenesis and Reactogenicity of Epidemic Vibrio cholerae by Zhang, Dalin, Xu, Zheng, Sun, Weiyun, Karaolis, David K R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text