Search Results - "Karanja, M."

The impact of Neglected Tropical Diseases (NTDs) on health and wellbeing in sub-Saharan Africa (SSA): A case study of Kenya by Ochola, Elizabeth A, Karanja, Diana M S, Elliott, Susan J

“…Neglected Tropical Diseases (NTDs) remain endemic to many regions of sub-Saharan Africa (SSA) left behind by socioeconomic progress. As such, these diseases…”
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A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of Schistosoma mansoni by Colley, Daniel G, Binder, Sue, Campbell, Carl, King, Charles H, Tchuem Tchuenté, Louis-Albert, N'Goran, Eliézer K, Erko, Berhanu, Karanja, Diana M S, Kabatereine, Narcis B, van Lieshout, Lisette, Rathbun, Stephen

“…We evaluated a commercial point-of-care circulating cathodic antigen (POC-CCA) test for assessing Schistosoma mansoni infection prevalence in areas at risk…”
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A Persistent Hotspot of Schistosoma mansoni Infection in a Five-Year Randomized Trial of Praziquantel Preventative Chemotherapy Strategies by Wiegand, Ryan E., Mwinzi, Pauline N. M., Montgomery, Susan P., Chan, YuYen L., Andiego, Kennedy, Omedo, Martin, Muchiri, Geoffrey, Ogutu, Michael O., Rawago, Fredrick, Odiere, Maurice R., Karanja, Diana M. S., Secor, W. Evan

“…During a trial of preventive chemotherapy strategies, a hotspot of Schistosoma mansoni infection was found. Significant differences between hotspot and…”
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Flexible Bayesian semiparametric mixed-effects model for skewed longitudinal data by Ferede, Melkamu M, Dagne, Getachew A, Mwalili, Samuel M, Bilchut, Workagegnehu H, Engida, Habtamu A, Karanja, Simon M

“…In clinical trials and epidemiological research, mixed-effects models are commonly used to examine population-level and subject-specific trajectories of…”
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Comparison of School-Based and Community-Wide Mass Drug Administration for Schistosomiasis Control in an Area of Western Kenya with High Initial Schistosoma mansoni Infection Prevalence: A Cluster Randomized Trial by Secor, W Evan, Wiegand, Ryan E, Montgomery, Susan P, Karanja, Diana M S, Odiere, Maurice R

“…We conducted a cluster randomized trial comparing the target population and timing of mass drug administration (MDA) with praziquantel for control of…”
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Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni by Melman, Sandra D, Steinauer, Michelle L, Cunningham, Charles, Kubatko, Laura S, Mwangi, Ibrahim N, Wynn, Nirvana Barker, Mutuku, Martin W, Karanja, Diana M S, Colley, Daniel G, Black, Carla L, Secor, William Evan, Mkoji, Gerald M, Loker, Eric S

“…The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the possible emergence of drug-resistant…”
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Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya by Shane, Hillary L, Verani, Jennifer R, Abudho, Bernard, Montgomery, Susan P, Blackstock, Anna J, Mwinzi, Pauline N M, Butler, Sara E, Karanja, Diana M S, Secor, W Evan

“…Although accurate assessment of the prevalence of Schistosoma mansoni is important for the design and evaluation of control programs, the most widely used…”
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Local tips, global impact: community-driven measures as avenues of promoting inclusion in the control of neglected tropical diseases: a case study in Kenya by Ochola, Elizabeth A, Karanja, Diana M. S, Elliott, Susan J

“…Abstract Background Neglected tropical diseases (NTDs) affect poor populations with little or no ‘political voice’ to influence control activities. While most…”
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Comparison of GeneXpert and line probe assay for detection of Mycobacterium tuberculosis and rifampicin-mono resistance at the National Tuberculosis Reference Laboratory, Kenya by Aricha, S A, Kingwara, L, Mwirigi, N W, Chaba, L, Kiptai, T, Wahogo, J, Otwabe, J S, Onyango, P O, Karanja, M, Ayieko, C, Matu, S W

“…The dual challenge of low diagnostic sensitivity of microscopy test and technical challenge of performing a TB culture test poses a problem for case detection…”
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Use of geospatial modeling to predict Schistosoma mansoni prevalence in Nyanza Province, Kenya by Woodhall, Dana M, Wiegand, Ryan E, Wellman, Michael, Matey, Elizabeth, Abudho, Bernard, Karanja, Diana M S, Mwinzi, Pauline M N, Montgomery, Susan P, Secor, W Evan

“…Schistosomiasis, a parasitic disease that affects over 200 million people, can lead to significant morbidity and mortality; distribution of single dose…”
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Is PCR the Next Reference Standard for the Diagnosis of Schistosoma in Stool? A Comparison with Microscopy in Senegal and Kenya by Meurs, Lynn, Brienen, Eric, Mbow, Moustapha, Ochola, Elizabeth A, Mboup, Souleymane, Karanja, Diana M S, Secor, W Evan, Polman, Katja, van Lieshout, Lisette

“…The current reference test for the detection of S. mansoni in endemic areas is stool microscopy based on one or more Kato-Katz stool smears. However, stool…”
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Lessons Learned in Conducting Mass Drug Administration for Schistosomiasis Control and Measuring Coverage in an Operational Research Setting by Binder, Sue, Campbell, Carl H, Castleman, Jennifer D, Kittur, Nupur, Kinung'hi, Safari M, Olsen, Annette, Magnussen, Pascal, Karanja, Diana M S, Mwinzi, Pauline N M, Montgomery, Susan P, Secor, William Evan, Phillips, Anna E, Dhanani, Neerav, Gazzinelli-Guimaraes, Pedro H, Clements, Michelle N, N'Goran, Eliézer K, Meite, Aboulaye, Utzinger, Jürg, Hamidou, Amina A, Garba, Amadou, Fleming, Fiona M, Whalen, Christopher C, King, Charles H, Colley, Daniel G

“…The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was created to conduct research that could inform programmatic decision-making…”
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Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes by Corstjens, Paul LAM, Nyakundi, Ruth K, de Dood, Claudia J, Kariuki, Thomas M, Ochola, Elizabeth A, Karanja, Diana MS, Mwinzi, Pauline NM, van Dam, Govert J

“…BACKGROUND: Accurate determination of Schistosoma infection rates in low endemic regions to examine progress towards interruption of transmission and…”
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Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections by Karanja, Diana M S, Awino, Emmy K, Wiegand, Ryan E, Okoth, Edward, Abudho, Bernard O, Mwinzi, Pauline N M, Montgomery, Susan P, Secor, W Evan

“…Mass drug administration (MDA) using praziquantel is the WHO-recommended approach for control of schistosomiasis. However, few studies have compared the impact…”
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Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial by Obarzanek, E, Sacks, F M, Vollmer, W M, Bray, G A, Miller, 3rd, E R, Lin, P H, Karanja, N M, Most-Windhauser, M M, Moore, T J, Swain, J F, Bales, C W, Proschan, M A

“…Effects of diet on blood lipids are best known in white men, and effects of type of carbohydrate on triacylglycerol concentrations are not well defined. Our…”
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Malacological survey and geographical distribution of vector snails for schistosomiasis within informal settlements of Kisumu City, western Kenya by Opisa, Selpha, Odiere, Maurice R, Jura, Walter GZO, Karanja, Diana MS, Mwinzi, Pauline NM

“…BACKGROUND: Although schistosomiasis is generally considered a rural phenomenon, infections have been reported within urban settings. Based on observations of…”
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High prevalence of schistosomiasis in Mbita and its adjacent islands of Lake Victoria, western Kenya by Odiere, Maurice R, Rawago, Fredrick O, Ombok, Maurice, Secor, William Evan, Karanja, Diana MS, Mwinzi, Pauline NM, Lammie, Patrick J, Won, Kimberly

“…BACKGROUND: Intestinal schistosomiasis continues to be a significant cause of morbidity among communities located around Lake Victoria and on its islands…”
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Community Health Workers' Experiences and Perspectives on Mass Drug Administration for Schistosomiasis Control in Western Kenya: The SCORE Project by OMEDO, Martin O, MATEY, Elizabeth J, AWITI, Alphonce, OGUTU, Michael, ALAII, Jane, KARANJA, Diana M. S, MONTGOMERY, Susan P, SECOR, W. Evan, MWINZI, Pauline N. M

“…The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) includes communitywide treatment in areas with ≥ 25% prevalence of…”
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Gaining and sustaining schistosomiasis control: study protocol and baseline data prior to different treatment strategies in five African countries by Ezeamama, Amara E, He, Chun-La, Shen, Ye, Yin, Xiao-Ping, Binder, Sue C, Campbell, Jr, Carl H, Rathbun, Stephen, Whalen, Christopher C, N'Goran, Eliézer K, Utzinger, Jürg, Olsen, Annette, Magnussen, Pascal, Kinung'hi, Safari, Fenwick, Alan, Phillips, Anna, Ferro, Josefo, Karanja, Diana M S, Mwinzi, Pauline N M, Montgomery, Susan, Secor, W Evan, Hamidou, Amina, Garba, Amadou, King, Charles H, Colley, Daniel G

“…The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in 2008 to answer strategic questions about schistosomiasis…”
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Can isoniazid preventive therapy be scaled up rapidly? Lessons learned in Kenya, 2014-2018 by Weyenga, H., Karanja, M., Onyango, E., Katana, A. K., Ng´ang´a, L. W., Sirengo, M., Ondondo, R. O., Wambugu, C., Waruingi, R. N., Muthee, R. W., Masini, E., Ngugi, E. W., Shah, N. S., Pathmanathan, I., Maloney, S., De Cock, K. M.

“…BACKGROUND: TB is the leading cause of mortality among people living with HIV (PLHIV), for whom isoniazid preventive therapy (IPT) has a proven mortality…”
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