Search Results - "Karandish, Sara"

Extracellular microRNA signature in chronic kidney disease by Muralidharan, Jagdeesan, Ramezani, Ali, Hubal, Monica, Knoblach, Susan, Shrivastav, Shashi, Karandish, Sara, Scott, Richard, Maxwell, Nirmal, Ozturk, Savas, Beddhu, Srinivasan, Kopp, Jeffrey B, Raj, Dominic S

“…MicroRNAs (miRNAs) are noncoding RNAs that regulate posttranscriptional gene expression. In this study we characterized the circulating and urinary miRNA…”
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21 Patient-derived HIV reservoirs can be stably engrafted into NSG mice and reactivated by latency-reversing agents in vivo by Adam Ward, Enock Charleus, Sara Karandish, Erika Benko, Colin Kovacs, Ali Ramezani, R. Brad Jones

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Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape by Pollack, Ross A., Jones, R. Brad, Pertea, Mihaela, Bruner, Katherine M., Martin, Alyssa R., Thomas, Allison S., Capoferri, Adam A., Beg, Subul A., Huang, Szu-Han, Karandish, Sara, Hao, Haiping, Halper-Stromberg, Eitan, Yong, Patrick C., Kovacs, Colin, Benko, Erika, Siliciano, Robert F., Ho, Ya-Chi

“…Despite antiretroviral therapy, HIV-1 persists in memory CD4+ T cells, creating a barrier to cure. The majority of HIV-1 proviruses are defective and…”
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Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells by Huang, Szu-Han, Ren, Yanqin, Thomas, Allison S, Chan, Dora, Mueller, Stefanie, Ward, Adam R, Patel, Shabnum, Bollard, Catherine M, Cruz, Conrad Russell, Karandish, Sara, Truong, Ronald, Macedo, Amanda B, Bosque, Alberto, Kovacs, Colin, Benko, Erika, Piechocka-Trocha, Alicja, Wong, Hing, Jeng, Emily, Nixon, Douglas F, Ho, Ya-Chi, Siliciano, Robert F, Walker, Bruce D, Jones, R Brad

“…The presence of persistent, latent HIV reservoirs in CD4+ T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm proposes to…”
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A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes by Jones, R Brad, Mueller, Stefanie, O'Connor, Rachel, Rimpel, Katherine, Sloan, Derek D, Karel, Dan, Wong, Hing C, Jeng, Emily K, Thomas, Allison S, Whitney, James B, Lim, So-Yon, Kovacs, Colin, Benko, Erika, Karandish, Sara, Huang, Szu-Han, Buzon, Maria J, Lichterfeld, Mathias, Irrinki, Alivelu, Murry, Jeffrey P, Tsai, Angela, Yu, Helen, Geleziunas, Romas, Trocha, Alicja, Ostrowski, Mario A, Irvine, Darrell J, Walker, Bruce D

“…Resting CD4+ T-cells harboring inducible HIV proviruses are a critical reservoir in antiretroviral therapy (ART)-treated subjects. These cells express little…”
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Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection by Ramezani, Ali, Dubrovsky, Larisa, Pushkarsky, Tatiana, Sviridov, Dmitri, Karandish, Sara, Raj, Dominic S, Fitzgerald, Michael L, Bukrinsky, Michael

“…Previous studies demonstrated that liver X receptor (LXR) agonists inhibit human immunodeficiency virus (HIV) replication by upregulating cholesterol…”
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Latent HIV reservoirs exhibit inherent resistance to elimination by [CD8.sup.+] T cells by Huang, Szu-Han, Ren, Yanqin, Thomas, Allison S, Chan, Dora, Mueller, Stefanie, Ward, Adam R, Patel, Shabnum, Bollard, Catherine M, Cruz, Conrad Russell, Karandish, Sara, Truong, Ronald, Macedo, Amanda B, Bosque, Alberto, Kovacs, Colin, Benko, Erika, Piechocka-Trocha, Alicja, Wong, Hing, Jeng, Emily, Nixon, Douglas F, Ho, Ya-Chi, Siliciano, Robert F, Walker, Bruce D, Jones, R. Brad

“…The presence of persistent, latent HIV reservoirs in [CD4.sup.+] T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm…”
Get full text

Latent HIV reservoirs exhibit inherent resistance to elimination by CD8^sup +^ T cells by Huang, Szu-Han, Ren, Yanqin, Thomas, Allison S, Chan, Dora, Mueller, Stefanie, Ward, Adam R, Patel, Shabnum, Bollard, Catherine M, Cruz, Conrad Russell, Karandish, Sara, Truong, Ronald, Macedo, Amanda B, Bosque, Alberto, Kovacs, Colin, Benko, Erika, Piechocka-Trocha, Alicja, Wong, Hing, Jeng, Emily, Nixon, Douglas F, Ho, Ya-Chi, Siliciano, Robert F, Walker, Bruce D, Jones, R Brad

“…The presence of persistent, latent HIV reservoirs in CD4+ T cells obstructs current efforts to cure infection. The so-called kick-and-kill paradigm proposes to…”
Get full text

Defective HIV-1 proviruses are expressed and can be recognized by cytotoxic T lymphocytes which shapes the proviral landscape by Pollack, Ross A., Jones, R. Brad, Pertea, Mihaela, Bruner, Katherine M., Martin, Alyssa R., Thomas, Allison S., Capoferri, Adam A., Beg, Subul A., Huang, Szu-Han, Karandish, Sara, Hao, Haiping, Halper-Stromberg, Eitan, Yong, Patrick C., Kovacs, Colin, Benko, Erika, Siliciano, Robert F., Ho, Ya-Chi

“…Despite antiretroviral therapy, HIV-1 persists in memory CD4 + T cells creating a barrier to cure. The majority of HIV-1 proviruses are defective and…”
Get full text

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4.sup.+ T-Cells to Recognition by Cytotoxic T-Lymphocytes by Jones, R. Brad, Mueller, Stefanie, O'Connor, Rachel, Rimpel, Katherine, Sloan, Derek D, Karel, Dan, Wong, Hing C, Jeng, Emily K, Thomas, Allison S, Whitney, James B, Lim, So-Yon, Kovacs, Colin, Benko, Erika, Karandish, Sara, Huang, Szu-Han, Buzon, Maria J, Lichterfeld, Mathias, Irrinki, Alivelu, Murry, Jeffrey P, Tsai, Angela, Yu, Helen, Geleziunas, Romas, Trocha, Alicja, Ostrowski, Mario A, Irvine, Darrell J, Walker, Bruce D

“…Resting CD4.sup.+ T-cells harboring inducible HIV proviruses are a critical reservoir in antiretroviral therapy (ART)-treated subjects. These cells express…”
Get full text