Search Results - "Karanam, Ashwin"
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Post-transplant survival in idiopathic pulmonary fibrosis patients concurrently listed for single and double lung transplantation
Published in The Journal of heart and lung transplantation (01-05-2016)“…Background Lung transplantation is a widely accepted treatment for patients with end-stage lung disease related to idiopathic pulmonary fibrosis (IPF)…”
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Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know
Published in Frontiers in pharmacology (09-01-2020)“…About 80% of the consumers worldwide use herbal medicine (HMs) or other natural products. The percentage may vary significantly (7%-55%) among pregnant women,…”
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Effect of body mass index on pharmacokinetics of paclitaxel in patients with early breast cancer
Published in Cancer medicine (Malden, MA) (01-05-2021)“…ABSTRACT Background Paclitaxel is dosed according to body surface area (BSA) but there is scant information on actual drug exposure in overweight and obese…”
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Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy
Published in Epilepsia (Copenhagen) (01-08-2019)“…Objective To evaluate the pharmacokinetics of a purified oral cannabidiol (CBD) capsule administered with and without food in adults with refractory epilepsy…”
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Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers With Epilepsy
Published in JAMA neurology (01-04-2020)“…There is limited information on infant drug exposure via breastfeeding by mothers who are receiving antiepileptic drug therapy. To provide direct, objective…”
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Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study
Published in JAMA neurology (01-04-2022)“…During pregnancy in women with epilepsy, lower blood concentrations of antiseizure medications can have adverse clinical consequences. To characterize…”
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Empiric dosing strategies to predict lamotrigine concentrations during pregnancy
Published in Pharmacotherapy (01-10-2023)“…Maintaining seizure control with lamotrigine is complicated by altered pharmacokinetics and existence of subpopulations in whom clearance increases or remains…”
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Lamotrigine clearance increases by 5 weeks gestational age: Relationship to estradiol concentrations and gestational age
Published in Annals of neurology (01-10-2018)“…Objective To determine how early lamotrigine clearance (LTG‐CL/F) increases during early pregnancy in women with epilepsy and to quantify the relationship of…”
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Population pharmacokinetics of Reditux™, a biosimilar Rituximab, in diffuse large B-cell lymphoma
Published in Cancer chemotherapy and pharmacology (01-08-2016)“…Purpose Rituximab (MabThera™, Roche) is a chimeric IgG1 monoclonal antibody targeting the CD20 surface antigen on normal and neoplastic B cells. It…”
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Bupivacaine Pharmacokinetics and Breast Milk Excretion of Liposomal Bupivacaine Administered After Cesarean Birth
Published in Obstetrics and gynecology (New York. 1953) (01-07-2020)“…OBJECTIVE:To evaluate bupivacaine concentrations in maternal plasma and transfer into breast milk in women undergoing liposomal bupivacaine infiltration in the…”
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Target Occupancy and Functional Inhibition of JAK3 and TEC Family Kinases by Ritlecitinib in Healthy Adults: An Open-Label, Phase 1 Study
Published in Journal of clinical pharmacology (01-01-2024)“…Ritlecitinib is a small molecule in clinical development that covalently and irreversibly inhibits Janus kinase 3 (JAK3) and the TEC family of kinases (BTK,…”
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Simultaneous Quantification of 13 Cannabinoids and Metabolites in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry in Adult Epilepsy Patients
Published in Therapeutic drug monitoring (01-06-2019)“…A sensitive, robust method was developed and validated to quantitate 13 major natural cannabinoid parent and metabolite compounds in human plasma at or below…”
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Quantitative Pharmacological Approaches for Characterizing Lamotrigine Pharmacokinetics in Special Populations of Pregnancy, Postpartum and Breastfeeding Infants to Prospectively Optimize Dosing
Published 01-01-2021“…Lamotrigine (LTG) is one of the most prescribed antiseizure medications (ASMs) in women with epilepsy during pregnancy and postpartum. Pregnancy-related…”
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Effect of various anticoagulants on the bioanalysis of drugs in rat blood: implication for pharmacokinetic studies of anticancer drugs
Published in SpringerPlus (20-12-2016)“…Background Pharmacokinetic studies are vital in development and optimization of drugs. While blood samples can be collected either in EDTA, heparin or citrate…”
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Neuro-ophthalmic complications in systemic lupus erythematosus: Case analysis and the literature review
Published in International journal of biomedical research (30-06-2015)Get full text
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Job's syndrome in a pediatric patient: Case report and the clinical review
Published in Indian journal of paediatric dermatology (01-04-2015)Get full text
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Job′s syndrome in a pediatric patient: Case report and the clinical review
Published in Indian journal of paediatric dermatology (2015)Get full text
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The impact of age and severity of comorbid illness on outcomes after isolated aortic valve replacement for aortic stenosis
Published in Risk management and healthcare policy (01-01-2015)“…This study examines outcomes in a national sample of patients undergoing isolated aortic valve replacement (AVR) for aortic stenosis, with particular focus on…”
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