Search Results - "Karamohamed, S."

Bioluminometric method for real-time detection of ATPase activity by Karamohamed, S, Guidotti, G

“…We have developed a real-time, simple, and sensitive method for the detection of ATP hydrolysis activity (ATPase) of apyrase (EC 3.6.1.5). The assay is based…”
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The -174 IL-6 GG genotype is associated with a reduced risk of type 2 diabetes mellitus in a family sample from the National Heart, Lung and Blood Institute's Framingham Heart Study by HERBERT, A, LIU, C, KARAMOHAMED, S, SCHILLER, J, LIU, J, YANG, Q, WILSON, P. W. F, CUPPLES, L. A, MEIGS, J. B

“…We evaluated the -174 IL-6 gene polymorphism as a risk factor for type 2 diabetes mellitus in a family-based analysis. We tested for associations between the…”
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Method for Real-Time Detection of Inorganic Pyrophosphatase Activity by Eriksson, Jonas, Karamohamed, Samer, Nyrén, Pål

“…A sensitive and simple method for real-time detection of inorganic pyrophosphatase (PPase) (EC 3.6.1.1) activity has been developed. The method is based on…”
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Recurrent 16p11.2 microdeletions in autism by Kumar, Ravinesh A., KaraMohamed, Samer, Sudi, Jyotsna, Conrad, Donald F., Brune, Camille, Badner, Judith A., Gilliam, T. Conrad, Nowak, Norma J., Cook, Edwin H., Dobyns, William B., Christian, Susan L.

“…Autism is a childhood neurodevelopmental disorder with a strong genetic component, yet the identification of autism susceptibility loci remains elusive. We…”
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Real-Time DNA Sequencing Using Detection of Pyrophosphate Release by Ronaghi, Mostafa, Karamohamed, Samer, Pettersson, Bertil, Uhlén, Mathias, Nyrén, Pål

“…An approach for real-time DNA sequencing without the need for electrophoresis has been developed. The approach relies on the detection of DNA polymerase…”
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Interactions of Interleukin‐6 Promoter Polymorphisms With Dietary and Lifestyle Factors and Their Association With Bone Mass in Men and Women From the Framingham Osteoporosis Study by Ferrari, Serge L, Karasik, David, Liu, Jun, Karamohamed, Samev, Herbert, Alan G, Cupples, L Adrienne, Kiel, Douglas P

“…Lifestyle and dietary factors may influence the association of IL‐6 polymorphisms with bone mass. In 1574 unrelated men and women from the Framingham Offspring…”
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Polymorphisms in the Insulin-Degrading Enzyme Gene Are Associated With Type 2 Diabetes in Men From the NHLBI Framingham Heart Study by KARAMOHAMED, Samer, DEMISSIE, Serkalem, ATWOOD, Larry D, CUPPLES, L. Adrienne, HERBERT, Alan, VOLCJAK, Jeannine, CHUNYU LIU, HEARD-COSTA, Nancy, JUN LIU, SHOEMAKER, Christina M, PANHUYSEN, Carolien I, MEIGS, James B, WILSON, Peter

“…Polymorphisms in the Insulin-Degrading Enzyme Gene Are Associated With Type 2 Diabetes in Men From the NHLBI Framingham Heart Study Samer Karamohamed 1 ,…”
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BDNF genetic variants are associated with onset age of familial Parkinson disease : GenePD Study by KARAMOHAMED, S, LATOURELLE, J. C, GUTTMAN, M, NICHOLSON, G, WILK, J. B, SAINT-HILAIRE, M, DESTEFANO, A. L, PRAKASH, R, TOBIN, S, WILLIAMSON, J, SUCHOWERSKY, O, LABELL, N, RACETTE, B. A, GROWDON, B. N. J, SINGER, C, WATTS, R, GOLDWURM, S, PEZZOLI, G, BAKER, K. B, GIROUX, M. L, PRAMSTALLER, P. P, BURN, D. J, CHINNERY, P, PERLMUTTER, J. S, SHERMAN, S, VIEREGGE, P, LITVAN, I, GUSELLA, J. F, MYERS, R. H, PARSIAN, A, WOOTEN, G. F, LEW, M, KLEIN, C, SHILL, H, GOLBE, L. I, MARK, M. H

“…Brain-derived neurotrophic factor (BDNF) stimulates neuronal growth and protects nigral dopamine neurons in animal models of Parkinson disease (PD). Therefore,…”
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Sepiapterin reductase expression is increased in Parkinson's disease brain tissue by Tobin, Jennifer E, Cui, Jing, Wilk, Jemma B, Latourelle, Jeanne C, Laramie, Jason M, McKee, Ann C, Guttman, Mark, Karamohamed, Samer, DeStefano, Anita L, Myers, Richard H

“…Abstract The PARK3 locus on chromosome 2p13 has shown linkage to both the development and age of onset of Parkinson's disease (PD). One candidate gene at this…”
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Influence of Alcohol Dehydrogenase 1C Polymorphism on the Alcohol—Cardiovascular Disease Association (from the Framingham Offspring Study) by Djoussé, Luc, Levy, Daniel, Herbert, Alan G., Wilson, Peter W.F., D’Agostino, Ralph B., Cupples, L. Adrienne, Karamohamed, Samer, Ellison, R. Curtis

“…Although moderate alcohol consumption is associated with a lower risk of cardiovascular disease (CVD), little is known of the effects of alcohol dehydrogenase…”
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A haplotype at the PARK3 locus influences onset age for Parkinson's disease: The GenePD study by KARAMOHAMED, S, DESTEFANO, A. L, CURRIE, L. J, WOOTEN, G. F, STACY, M, SAINT-HILAIRE, M, FELDMAN, R. G, SULLIVAN, K. M, XU, G, WATTS, R, GROWDON, J, LEW, M, WILK, J. B, WATERS, C, VIEREGGE, P, PRAMSTALLER, P. P, KLEIN, C, RACETTE, B. A, PERLMUTTER, J. S, PARSIAN, A, SINGER, C, MONTGOMERY, E, BAKER, K, SHOEMAKER, C. M, GUSELLA, J. F, FINK, S. J, MYERS, R. H, HERBERT, A, GOLBE, L. I, MARK, M. H, LAZZARINI, A. M, SUCHOWERSKY, O, LABELLE, N, GUTTMAN, M

“…To identify a haplotype influencing onset age for Parkinson's disease (PD) in the PARK3 region on chromosome 2p13. Single nucleotide polymorphisms (SNP)…”
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Real-Time Detection and Quantification of Adenosine Triphosphate Sulfurylase Activity by a Bioluminometric Approach by Karamohamed, Samer, Nyrén, Pål

“…A real-time, sensitive, and simple assay for detection and quantification of adenosine triphosphate sulfurylase (ATP:sulfate adenylytransferase, EC 2.7.7.4)…”
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Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study by Karamohamed, Samer, Golbe, L.I., Mark, M.H., Lazzarini, A.M., Suchowersky, O., Labelle, N., Guttman, Mark, Currie, L.J., Wooten, G.F., Stacy, M., Saint-Hilaire, M., Feldman, R.G., Liu, J., Shoemaker, C.M., Wilk, J.B., DeStefano, A.L., Latourelle, J.C., Xu, G., Watts, R., Growdon, J., Lew, M., Waters, C., Vieregge, P., Pramstaller, P.P., Klein, C., Racette, B.A., Perlmutter, J.S., Parsian, A., Singer, Carlos, Montgomery, E., Baker, K., Gusella, J.F., Herbert, A., Myers, R.H.

“…Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of…”
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Detection of Single-Base Changes Using a Bioluminometric Primer Extension Assay by Nyrén, Pål, Karamohamed, Samer, Ronaghi, Mostafa

“…A rapid bioluminometric technique for real-time detection of known single-base changes is presented. The concept relies on the measurement of the difference in…”
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BDNF genetic variants are associated with onset age of familial Parkinson disease: Gene PD Study by Karamohamed, S., Latourelle, J. C., Racette, B. A., Perlmutter, J. S., Wooten, G. F., Lew, M., Klein, C., Shill, H., Golbe, L. I., Mark, M. H., Guttman, M., Nicholson, G., Wilk, J. B., Saint-Hilaire, M., DeStefano, A. L., Prakash, R., Tobin, S., Williamson, J., Suchowersky, O., Labell, N., Growdon, B.N.J., Singer, C., Watts, R., Goldwurm, S., Pezzoli, G., Baker, K. B., Giroux, M. L., Pramstaller, P. P., Burn, D. J., Chinnery, P., Sherman, S., Vieregge, P., Litvan, I., Gusella, J. F., Myers, R. H., Parsian, A.

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Production, purification, and luminometric analysis of recombinant Saccharomyces cerevisiae MET3 adenosine triphosphate sulfurylase expressed in Escherichia coli by Karamohamed, S, Nilsson, J, Nourizad, K, Ronaghi, M, Pettersson, B, Nyrén, P

“…ATP sulfurylase cDNA from MET3 on chromosome X of Saccharomyces cerevisiae was amplified and cloned, and recombinant ATP sulfurylase was expressed in…”
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A haplotype at the PARK3 locus influences onset age for Parkinson’s disease: The Gene PD study by Karamohamed, S., DeStefano, A. L., Wilk, J. B., Shoemaker, C. M., Golbe, L. I., Mark, M. H., Lazzarini, A. M., Suchowersky, O., Labelle, N., Guttman, M., Currie, L. J., Wooten, G. F., Stacy, M., Saint-Hilaire, M., Feldman, R. G., Sullivan, K. M., Xu, G., Watts, R., Growdon, J., Lew, M., Waters, C., Vieregge, P., Pramstaller, P. P., Klein, C., Racette, B. A., Perlmutter, J. S., Parsian, A., Singer, C., Montgomery, E., Baker, K., Gusella, J. F., Fink, S. J., Myers, R. H., Herbert, A.

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Real-time bioluminometric method for detection of nucleoside diphosphate kinase activity by Karamohamed, S, Nordström, T, Nyrén, P

“…A real-time, simple and sensitive method for detection of nucleoside diphosphate (NDP) kinase activity has been developed. The assay is based on detection of…”
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Bioluminometric method for real-time detection of reverse transcriptase activity by Karamohamed, S, Ronaghi, M, Nyrén, P

“…A simple and sensitive technique for detection of reverse transcriptase (RT) activity in real time has been developed. The technique is based on continuous…”
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