Sero-epidemioloical survey on African horse sickness virus among horses in Khartoum State, Central Sudan

African horse sickness virus (AHSV) is an infectious non contagious insect-transmitted double-stranded (ds) RNA orbivirus of the family Reoviridae. AHSV causes an often fatal hemorrhagic infection with high mortality among selected breeds of Arabian horses. This study was conducted to avail some inf...

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Bibliographic Details
Published in:	BMC veterinary research Vol. 14; no. 1; p. 230
Main Authors:	Karamalla, Siham T, Gubran, Ahmed I, Adam, Ibrahim A, Abdalla, Tamadur M, Sinada, Reem O, Haroun, Eltahir M, Aradaib, Imadeldin E
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 01-08-2018 BioMed Central BMC
Subjects:	African horse sickness African Horse Sickness - epidemiology African Horse Sickness - etiology African Horse Sickness - virology African Horse Sickness Virus AHSV Animals Antibodies, Bacterial - immunology Antigens Disease Distribution Double-stranded RNA ELISA Enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - veterinary Enzymes Epidemiology equines Female Health aspects Health risks Hemorrhage Horses Horses - virology Immunoglobulin G Immunoglobulin G - immunology Immunoglobulins Infections Male Pest outbreaks Polymerase chain reaction Prevalence Reoviridae Reoviruses Risk Factors Seroepidemiologic Studies Sudan Sudan - epidemiology Surveillance Survey Surveys and Questionnaires Veterinary research Viral infections Viruses Sudan Ethiopia Survey AHSV Epidemiology Sudan equines ELISA
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Summary:	African horse sickness virus (AHSV) is an infectious non contagious insect-transmitted double-stranded (ds) RNA orbivirus of the family Reoviridae. AHSV causes an often fatal hemorrhagic infection with high mortality among selected breeds of Arabian horses. This study was conducted to avail some information with regard to the prevalence and associated risk factors of AHSV among ecotype breeds of horses in central Sudan. Sera were collected from 320 horses, which were selected randomly from four localities and employed in the study. A competitive enzyme-linked immunosorbent assay (cELISA) was used to screen sampled sera for AHSV-specific immunoglobulin G (Ig G) antibodies. Seropositivity to AHSV Ig G was detected in 275 out of the 320 horse sera, thus accounting for a prevalence rate of 85.9%. Potential risk factors to AHSV infection were reported to be associated with horse breed (OR = 5.0, CI = 0.07-2.104, p-value = 0.039) and activity of the horse (OR = 3.21, CI = 0.72-1.48, p- value = 0.008). The high prevalence of AHSV in Khartoum State of Central Sudan necessitates the need for continuous surveillance for AHSV infection to prevent a possible disease outbreak in this region of the African continent.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1746-6148 1746-6148
DOI:	10.1186/s12917-018-1554-5