Search Results - "Karamali, Negin"
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Decoding contextual crosstalk: revealing distinct interactions between non-coding RNAs and unfolded protein response in breast cancer
Published in Cancer cell international (11-03-2024)“…Breast cancer is significantly influenced by endoplasmic reticulum (ER) stress, impacting both its initiation and progression. When cells experience an…”
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The axis of long non-coding RNA MALAT1/miR-1-3p/CXCR4 is dysregulated in patients with diabetic neuropathy
Published in Heliyon (01-03-2022)“…Diabetic neuropathy (DN) is a prevalent complication of diabetes mellitus characterized by pain and inflammation. Long non-coding RNAs (lncRNAs) have been…”
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Molecular mechanism of lncRNAs in pathogenesis and diagnosis of auto-immune diseases, with a special focus on lncRNA-based therapeutic approaches
Published in Life sciences (1973) (01-01-2024)“…Autoimmune diseases are a diverse set of conditions defined by organ damage due to abnormal innate and acquired immune system responses. The pathophysiology of…”
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HRD1 in human malignant neoplasms: Molecular mechanisms and novel therapeutic strategy for cancer
Published in Life sciences (1973) (15-07-2022)“…In tumor cells, the endoplasmic reticulum (ER) plays an essential role in maintaining cellular proteostasis by stimulating unfolded protein response (UPR)…”
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Casting Light on the Janus-Faced HMG-CoA Reductase Degradation Protein 1: A Comprehensive Review of Its Dualistic Impact on Apoptosis in Various Diseases
Published in Molecular neurobiology (01-09-2024)“…Nowadays, it is well recognized that apoptosis, as a highly regulated cellular process, plays a crucial role in various biological processes, such as cell…”
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Efficacy of DMARDs and methylprednisolone treatment on the gene expression levels of HSPA5, MMD, and non-coding RNAs MALAT1, H19, miR-199a-5p, and miR-1-3p, in patients with rheumatoid arthritis
Published in International immunopharmacology (01-07-2022)“…•MALAT1 and H19 may be candidates as potential biomarkers in rheumatoid arthritis.•MALAT1 and H19 positively correlated with MMD and RA severity.•DMARDs plus…”
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Autoimmune thyroid disorders and polycystic ovary syndrome: Tracing links through systematic review and meta-analysis
Published in Journal of reproductive immunology (01-06-2024)“…Polycystic Ovary Syndrome (PCOS) and Autoimmune Thyroiditis (AIT) are two prevalent endocrine disorders affecting women, often coexisting within the same…”
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Overexpression of Synoviolin and miR-125a-5p, miR-19b-3p in peripheral blood of rheumatoid arthritis patients after treatment with conventional DMARDs and methylprednisolone
Published in Clinical rheumatology (2024)“…Purpose SYVN1 is an endoplasmic reticulum (ER)-resident E3 ubiquitin ligase that has an essential function along with SEL1L in rheumatoid arthritis (RA)…”
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Dysregulation of Long Noncoding RNA NEAT1/miR-199a-5/BiP Axis in Patients with Diabetic Neuropathy
Published in Laboratory medicine (07-03-2023)“…Abstract Objective Diabetic neuropathy (DN) is a type of nerve damage and the most common complication of diabetes. Regarding the association between…”
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