Search Results - "Karam, Sherif"

Development of a therapeutic model of precancerous liver using crocin-coated magnetite nanoparticles by El-Kharrag, Rkia, Amin, Amr, Hisaindee, Soleiman, Greish, Yaser, Karam, Sherif M

“…Despite considerable advances in understanding hepatocellular carcinoma, it is one of the common and deadliest cancers worldwide. Hence, increasing efforts are…”
Get full text

Long-Term Vitamin D Deficiency Results in the Inhibition of Cell Proliferation and Alteration of Multiple Gastric Epithelial Cell Lineages in Mice by Sirajudeen, Shaima, Shah, Iltaf, Ayoub, Mohammed Akli, Karam, Sherif M, Al Menhali, Asma

“…Over one billion people globally are vitamin D (VD) deficient. Studies on the biological roles of VD are numerous but very little on the stomach. This project…”
Get full text

Genetic polymorphisms and protein expression of P53 and BRCA1 in preneoplastic and neoplastic rat mammary glands by Al-Dhaheri, Wafa, Hassouna, Imam, Karam, Sherif M

“…Breast cancer is the most common type of cancer and the leading cause of cancer-related deaths among women in the United Arab Emirates and worldwide. Although…”
Get full text

Ghrelin knockout mice show decreased voluntary alcohol consumption and reduced ethanol-induced conditioned place preference by Bahi, Amine, Tolle, Virginie, Fehrentz, Jean-Alain, Brunel, Luc, Martinez, Jean, Tomasetto, Catherine-Laure, Karam, Sherif M.

“…► Ghrelin KO displayed lower ethanol-CPP. ► Ghrelin receptor antagonist JMV2959 reduced CPP-expression in C57BL/6 mice. ► Ghrelin KO displayed lower…”
Get full text

Seven-Month Vitamin D Deficiency Inhibits Gastric Epithelial Cell Proliferation, Stimulates Acid Secretion, and Differentially Alters Cell Lineages in the Gastric Glands by Sirajudeen, Shaima, Shah, Iltaf, Karam, Sherif M, Al Menhali, Asma

“…Vitamin D (VD) deficiency can result from insufficiency of either light exposure or VD intake. We investigated the biological effects of VD deficiency for 7…”
Get full text

Probiotics Upregulate Trefoil Factors and Downregulate Pepsinogen in the Mouse Stomach by Khoder, Ghalia, Al-Yassir, Farah, Al Menhali, Asma, Saseedharan, Prashanth, Sugathan, Subi, Tomasetto, Catherine, Karam, Sherif M

“…Probiotics are used in the management of some gastrointestinal diseases. However, little is known about their effects on normal gastric epithelial biology. The…”
Get full text

Overgrowth of Squamocolumnar Junction and Dysregulation of Stem Cell Lineages in the Stomach of Vitamin A-Deficient Mice by Vins, Neethu, Sugathan, Subi, Al Menhali, Asma, Karam, Sherif M

“…Junctional epithelia are common sites for pathological transformations. In mice, the stratified epithelium of the forestomach joins the simple glandular…”
Get full text

BioMOF-Based Anti-Cancer Drug Delivery Systems by Elmehrath, Sandy, Nguyen, Ha L, Karam, Sherif M, Amin, Amr, Greish, Yaser E

“…A variety of nanomaterials have been developed specifically for biomedical applications, such as drug delivery in cancer treatment. These materials involve…”
Get full text

A focus on parietal cells as a renewing cell population by Karam, Sherif M

“…The fact that the acidsecreting parietal cells undergo continuous renewal has been ignored by many gastroenterologists and cell biologists. In the past, it was…”
Get full text

SMARCAD1 in Breast Cancer Progression by Arafat, Kholoud, Al Kubaisy, Elham, Sulaiman, Shahrazad, Karam, Sherif M., Al Natour, Zeina, Hassan, Ahmed H., Attoub, Samir 

“…Background/Aims: Breast cancer is the most common cancer in women worldwide, and within this cancer type, triple-negative breast cancers have the worst…”
Get full text

Vitamin D Is Necessary for Murine Gastric Epithelial Homeostasis by Ali, Ifrah Ismail, Shah, Iltaf, Marzouk, Sayed, Karam, Sherif M., Al Menhali, Asma

“…Unlike other organs, the importance of VD in a normal stomach is unknown. This study focuses on understanding the physiological role of vitamin D in gastric…”
Get full text

Growth and Differentiation of Dental Stem Cells of Apical Papilla on Polycaprolactone Scaffolds by Jamal, Mohamed, Greish, Yaser, Chogle, Sami, Goodis, Harold, Karam, Sherif M

“…Biodegradable scaffolds are useful tools in the field of tissue engineering and regenerative medicine. The aim of this study was to test the potential of the…”
Get more information

Potential role of probiotics in the management of gastric ulcer by KHODER, GHALIA, AL-MENHALI, ASMA A, AL-YASSIR, FARAH, KARAM, SHERIF M

“…Gastric ulcer is one of the most common chronic gastrointestinal diseases characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H…”
Get full text

Origanum majorana essential oil decreases lung tumor growth and metastasis in vitro and in vivo by Arafat, Kholoud, Sulaiman, Shahrazad, Al-Azawi, Aya Mudhafar, Yasin, Javed, Sugathan, Subi, Nemmar, Abderrahim, Karam, Sherif, Attoub, Samir

“…Current targeted- and immuno-therapies have prolonged the overall survival of non-small cell lung cancer (NSCLC) patients by few months in a small percentage…”
Get full text

Decreased acylated and total ghrelin levels in bipolar disorder patients recovering from a manic episode by Abdel Aziz, Karim, Al-Mugaddam, Fadwa, Sugathan, Subi, Saseedharan, Prashanth, Jouini, Tarek, Elamin, Mohamed Elhassan, Moselhy, Hamdy, Aly El-Gabry, Dina, Arnone, Danilo, Karam, Sherif M

“…To date, only few studies have investigated ghrelin levels in bipolar disorders, and all have exclusively measured acylated ghrelin, with none investigating…”
Get full text

Modulation of Stem Cell Progeny by Probiotics during Regeneration of Gastric Mucosal Erosions by Al-Yassir, Farah, Khoder, Ghalia, Sugathan, Subi, Saseedharan, Prashanth, Al Menhali, Asma, Karam, Sherif M.

“…Patients with gastric mucosal erosions are predisposed to chronic gastritis, ulcer or even cancer. The repair of mucosal erosions involves several events…”
Get full text

Helicobacter pylori Evolution during Progression from Chronic Atrophic Gastritis to Gastric Cancer and Its Impact on Gastric Stem Cells by Giannakis, Marios, Chen, Swaine L., Karam, Sherif M., Engstrand, Lars, Gordon, Jeffrey I.

“…We have characterized the adaptations of Helicobacter pylori to a rarely captured event in the evolution of its impact on host biology-the transition from…”
Get full text

Cellular Origin of Gastric Cancer by Karam, Sherif M.

“…Gastric cancer is the second leading cause of cancer deaths worldwide. Although the link between Helicobacter pylori infection and gastric cancer is well…”
Get full text

Gastric parietal cell vacuolation mimicking gastric carcinoma by Rahman, Muhammad Amin ur, Karam, Sherif M

Get full text

Mouse models demonstrating the role of stem/progenitor cells in gastric carcinogenesis by Karam, Sherif M

“…Advances have been made in identifying the gastric epithelial stem cells and their immediate descendents which act as uncommitted or committed progenitors…”
Get full text