Search Results - "Karalis, Theodoros"
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Targeting Hyaluronan Synthesis in Cancer: A Road Less Travelled
Published in Biologics (Basel, Switzerland) (12-12-2023)“…Hyaluronan is one of the major components of the extracellular matrix and is involved in the regulation of multiple processes in both human physiology and…”
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Hyaluronan-CD44 axis orchestrates cancer stem cell functions
Published in Cellular signalling (01-11-2019)“…The prominent role of CD44 in tumor cell signaling together with its establishment as a cancer stem cell (CSC) marker for various tumor entities imply a key…”
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Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors
Published in Matrix biology (01-05-2019)“…The malignant phenotype of various cancers is linked to enhanced expression of hyaluronan, a pro-angiogenic glycosaminoglycan whose expression is suppressed by…”
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The Emerging Role of LPA as an Oncometabolite
Published in Cells (Basel, Switzerland) (01-04-2024)“…Lysophosphatidic acid (LPA) is a phospholipid that displays potent signalling activities that are regulated in both an autocrine and paracrine manner. It can…”
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Cold Atmospheric Plasma Attenuates Breast Cancer Cell Growth Through Regulation of Cell Microenvironment Effectors
Published in Frontiers in oncology (17-01-2022)“…Breast cancer exists in multiple subtypes some of which still lack a targeted and effective therapy. Cold atmospheric plasma (CAP) has been proposed as an…”
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Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells
Published in Matrix biology plus (01-05-2020)“…The oncogenic role of hyaluronan in several aspects of tumor biology has been well established. Recent studies by us and others suggest that inhibition of…”
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Intracellular hyaluronan: Importance for cellular functions
Published in Seminars in cancer biology (01-05-2020)“…Hyaluronan-rich matrices are abundant in ECM and are involved in biological processes, such as cell growth and migration. Hyaluronan is synthesized by the…”
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Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells
Published in Cancers (25-11-2022)“…Breast cancer is a common cancer in women. Breast cancer cells synthesize large amounts of hyaluronan to assist their proliferation, survival, migration and…”
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Integrated effects on the shrinkage stresses from the water loss in soft cohesive soils
Published in International journal of engineering science (01-03-2003)“…The objective of this paper is to explain field shrinkage-crack associations formed on a homogeneous soil surface layer due to withdrawal of the interstitial…”
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Αξιολόγηση επενδυτικού σχεδίου δημιουργίας ενός Κέντρου Φυσικής και Ιατρικής Αποκατάστασης
Published 01-01-2015“…Η ίδρυση ενός Κέντρου Φυσικής και Ιατρικής Αποκατάστασης, αποτελεί μια σύνθετη διαδικασία, καθώς απαιτεί το συνδυασμό επιστημονικών γνώσεων πάνω στο…”
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Dissertation