Search Results - "Karalay, Özlem"
-
1
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Published in Nature communications (22-03-2016)“…Germline removal provokes longevity in several species and shifts resources towards survival and repair. Several Caenorhabditis elegans transcription factors…”
Get full text
Journal Article -
2
Translating niche-derived signals into neurogenesis: The function of Prox1 in the adult hippocampus
Published in Cell cycle (Georgetown, Tex.) (15-07-2011)“…Comment on: Karalay O, et al. Proc Natl Acad Sci USA 2011; 108:5807-12…”
Get full text
Journal Article -
3
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Published in Nature (London) (10-01-2013)“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
Get full text
Journal Article -
4
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (05-04-2011)“…Neural stem cells (NSCs) generate new granule cells throughout life in the mammalian hippocampus. Canonical Wnt signaling regulates the differentiation of NSCs…”
Get full text
Journal Article -
5
Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus
Published in PLoS biology (01-11-2008)“…Newborn granule cells become functionally integrated into the synaptic circuitry of the adult dentate gyrus after a morphological and electrophysiological…”
Get full text
Journal Article -
6
Ageing-associated changes in transcriptional elongation influence longevity
Published in Nature (London) (27-04-2023)“…Physiological homeostasis becomes compromised during ageing, as a result of impairment of cellular processes, including transcription and RNA splicing 1 – 4 …”
Get full text
Journal Article