Search Results - "Karaki, Sachiko"

HLA-B51 transgenic mice as recipients for production of polymorphic HLA-A, B-specific antibodies by Karaki, S, Kariyone, A, Kato, N, Kano, K, Iwakura, Y, Takiguchi, M

“…In the present study, we attempted to produce polymorphic antibodies for HLA-A, B, And C antigens in HLA-B51 TGM. TGM were produced by injecting the 6.4…”
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Characterization of beta-tricalcium phosphate as a novel immunomodulator by Tai, Sachiko, Cheng, Jin-Yan, Ishii, Hidee, Akimoto, Shingo, Satoh, Takatomo, Yamamoto, Kazumi, Nakajima, Takashi, Karaki, Sachiko, Suzuki, Emiko, Yamaguchi, Ken, Maruyama, Kouji

“…Calcium phosphate (CaP) ceramics including hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) have been widely used for bone substitution in orthopedic,…”
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Development and validation of algorithms for measuring G‐protein coupled receptor activation in cells using the LSC‐based imaging cytometer platform by Ozawa, Kazuo, Hudson, Christine C., Wille, Kirsten R., Karaki, Sachiko, Oakley, Robert H.

“…Background A cell‐based assay system (Transfluor) has been developed for measurement of G‐protein coupled receptor (GPCR) activity by using cells transfected…”
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Dengue virus-specific, HLA-B35-restricted, human CD8+ cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities by Livingston, PG, Kurane, I, Dai, LC, Okamoto, Y, Lai, CJ, Men, R, Karaki, S, Takiguchi, M, Ennis, FA

“…Dengue virus infections are a major cause of morbidity and mortality in tropical and subtropical areas of the world. We analyzed dengue virus-specific CD8+…”
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Beta-chain broadens range of CD8 recognition for MHC class I molecule by Karaki, S, Tanabe, M, Nakauchi, H, Takiguchi, M

“…It is known that the alpha-chain of CD8 binds to a negatively charged loop composed of residues 223 to 229 on MHC class I Ag and that binding of CD8 alpha…”
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Identification of HTLV-1-Specific CTL Directed against Synthetic and Naturally Processed Peptides in HLA-B3501 Transgenic Mice by Schönbach, Christian, Nokihara, Kiyoshi, Bangham, Charles R.M., Kariyone, Ai, Karaki, Sachiko, Shida, Hisatoshi, Takatsu, Kiyoshi, Egawa, Kohji, Wiesmüller, Karl-Heinz, Takiguchi, Masafumi

“…Previous studies of CTL responses to influenza peptides in HLA single transgenic mice resulted in the identification of at most one immunodominant epitope…”
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Antigen recognition by the T cell receptor is enhanced by CD8 alpha-chain binding to the alpha 3 domain of MHC class I molecules, not by signaling via the cytoplasmic domain of CD8 alpha by Tanabe, M, Karaki, S, Takiguchi, M, Nakauchi, H

“…The binding specificities and function of mouse CD8 were studied using a CD4-CD8- allospecific T cell hybridoma, chimeric class I MHC molecules, and a CD8…”
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The structure of HLA-B35 suggests that it is derived from HLA-Bw58 by two genetic mechanisms by OOBA, T, HAYASHI, H, KARAKI, S, TANABE, M, KANO, K, TAKIGUCHI, M

“…The primary structure of HLA-B51 and HLA-Bw52 suggested that HLA-B51 was derived from HLA-Bw52 by the combination of a genetic exchange with HLA-B8 and a point…”
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Structural analysis of HLA-B40 epitopes by Kawaguchi, G, Kato, N, Kashiwase, K, Karaki, S, Kohsaka, T, Akaza, T, Kano, K, Takiguchi, M

“…Two genes encoding HLA-B60 or HLA-B61 were cloned from Japanese and the exons of their genes were sequenced. One silent mutation was observed at the exon 1…”
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Effect of single amino acid substitution at residue 167 of HLA-B51 on binding of antibodies and recognition of T cells by Nakayama, S, Kawaguchi, G, Karaki, S, Nagao, T, Uchida, H, Kashiwase, K, Akaza, T, Nasuno, T, Takiguchi, M

“…We recently showed that a single amino acid substitution of tryptophane into glycine at residue 167 facing the "A pocket" forms a novel HLA-B51 subtype,…”
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Molecular analysis of HLA-B39 subtypes by KATO, N, KARAKI, S, KASHIWASE, K, MÜLLER, C, AKAZA, T, JUJI, T, KANO, K, TAKIGUCHI, M

“…Serological studies have suggested the presence of a new HLA-B39 subtype (B39.2) in the Japanese population. To identify the new HLA-B39 subtype and compare it…”
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Identification of the gene encoding a novel HLA-B39 subtype. Two amino acid substitutions on the beta-sheet out of the peptide-binding floor form a novel serological epitope by Ogawa, A, Tokunaga, K, Nakajima, F, Kikuchi, A, Karaki, S, Kashiwase, K, Ge, J, Hannestad, K, Juji, T, Takiguchi, M

“…Serological analysis suggests the existence of a novel HLA-B39 subtype (HLA-B39N) in the Japanese population. To identify this novel allele, a gene encoding…”
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Allodeterminants and evolution of a novel HLA-B5 CREG antigen, HLA-B SNA by Sekimata, M, Hiraiwa, M, Andrien, M, Dupont, E, Karaki, S, Yamamoto, J, Kano, K, Takiguchi, M

“…A novel HLA-B5 CREG gene, HLA-B SNA was cloned and the primary structure was determined. The sequence data showed that HLA-B SNA was identical to HLA-B51…”
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T cell can recognize the allospecificities formed by the substitution of amino acids associated with HLA-Bw4/Bw6 public epitopes by Hiraiwa, M, Yamamoto, J, Matsumoto, K, Karaki, S, Nagao, T, Kano, K, Takiguchi, M

“…Our previous studies clearly showed that HLA-B35 and HLA-Bw53 differed only by the amino acids associated with HLA-Bw4/Bw6 epitopes, in that the former…”
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Two subtypes of HLA-B51 differing by substitution at position 171 of the α2 helix by KAWAGUCHI, G, HILDEBRAND, W. H, JUJI, T, PARHAM, P, TAKIGUCHI, M, HIRAIWA, M, KARAKI, S, BAGAO, T, AKIYAMA, N, UCHIDA, H, HASHIWASE, K, AKAZA, T, WILLIAMS, R. C

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Two subtypes of HLA-B51 differing by substitution at position 171 of the ?2 helix by Kawaguchi, Go, Hildebrand, WilliamH, Hiraiwa, Masaki, Karaki, Sachiko, Nagao, Takeshi, Akiyama, Nobuo, Uchida, Hisanori, Kashiwase, Kouichi, Akaza, Tatsuya, Williams, RobertC, Juji, Takeo, Parham, Peter, Takiguchi, Masafumi

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The structure ofHLA-B35 suggests that it is derived fromHLA-Bw58 by two genetic mechanisms by Ooba, Takashi, Hayashi, Hideyuki, Karaki, Sachiko, Tanabe, Manabu, Kano, Kyoichi, Takiguchi, Masafumi

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