Search Results - "Karagoz, G."

Update on treatment options for spinal brucellosis by Ulu-Kilic, A., Karakas, A., Erdem, H., Turker, T., Inal, A.S., Ak, O., Turan, H., Kazak, E., Inan, A., Duygu, F., Demiraslan, H., Kader, C., Sener, A., Dayan, S., Deveci, O., Tekin, R., Saltoglu, N., Aydin, M., Horasan, E.S., Gul, H.C., Ceylan, B., Kadanali, A., Karabay, O., Karagoz, G., Kayabas, U., Turhan, V., Engin, D., Gulsun, S., Elaldı, N., Alabay, S.

“…We evaluated the efficacy and tolerability of antibiotic regimens and optimal duration of therapy in complicated and uncomplicated forms of spinal brucellosis…”
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The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum by Karagöz, G Elif, Acosta-Alvear, Diego, Walter, Peter

“…Most of the secreted and plasma membrane proteins are synthesized on membrane-bound ribosomes on the endoplasmic reticulum (ER). They require engagement of…”
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Dosimetric Evaluation of Different Radiation Therapy Techniques in Left-Sided Breast Cancer by Haydaroglu, A, Hazeral, Y.Z, Hazeral, B, Duran, O, Karagoz, G, Olacak, N, Alanyali, S

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Predictors for limb loss among patient with diabetic foot infections: an observational retrospective multicentric study in Turkey by Saltoglu, N., Yemisen, M., Ergonul, O., Kadanali, A., Karagoz, G., Batirel, A., Ak, O., Eraksoy, H., Cagatay, A., Vatan, A., Sengoz, G., Pehlivanoglu, F., Aslan, T., Akkoyunlu, Y., Engin, D., Ceran, N., Erturk, B., Mulazimoglu, L., Oncul, O., Ay, H., Sargin, F., Ozgunes, N., Simsek, F., Yildirmak, T., Tuna, N., Karabay, O., Yasar, K., Uzun, N., Kucukardali, Y., Sonmezoglu, M., Yilmaz, F., Tozalgan, U., Ozer, S., Ozyazar, M.

“…We aimed to investigate the predictors for limb loss among patients with diabetes who have complicated skin/soft-tissue infections. In this observational…”
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Evaluation of MLC Leaf Position Accuracy for Static and Dynamic IMRT Treatments Using DAVID In Vivo Dosimetric System by Karagoz, G, Zorlu, F, Yeğiner, M, Yıldız, D, Gürkaynak, M

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An unfolded protein-induced conformational switch activates mammalian IRE1 by Karagöz, G Elif, Acosta-Alvear, Diego, Nguyen, Hieu T, Lee, Crystal P, Chu, Feixia, Walter, Peter

“…The unfolded protein response (UPR) adjusts the cell's protein folding capacity in the endoplasmic reticulum (ER) according to need. IRE1 is the most conserved…”
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Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action by Karagöz, G. Elif, Duarte, Afonso M.S., Akoury, Elias, Ippel, Hans, Biernat, Jacek, Morán Luengo, Tania, Radli, Martina, Didenko, Tatiana, Nordhues, Bryce A., Veprintsev, Dmitry B., Dickey, Chad A., Mandelkow, Eckhard, Zweckstetter, Markus, Boelens, Rolf, Madl, Tobias, Rüdiger, Stefan G.D.

“…Protein folding in the cell relies on the orchestrated action of conserved families of molecular chaperones, the Hsp70 and Hsp90 systems. Hsp70 acts early and…”
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Effect of cultivar and harvest time on C6 and C5 volatile compounds of Turkish olive oils by Karagoz, Sermin G., Yilmazer, Mustafa, Ozkan, Gulcan, Carbonell-Barrachina, Ángel A., Kiralan, Mustafa, Ramadan, Mohamed Fawzy

“…Aroma is an important quality criterion for extra virgin olive oil. The goal of this study was to determine C 6 and C 5 volatile compounds in different Turkish…”
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Hsp90 interaction with clients by Karagöz, G. Elif, Rüdiger, Stefan G.D.

“…•Hsp90 recognises substrate by an extended interface with scattered hydrophobics.•Hsp90 binds folded proteins, folding intermediates, and disordered…”
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Endoplasmic reticulum: Monitoring and maintaining protein and membrane homeostasis in the endoplasmic reticulum by the unfolded protein response by Kettel, Paulina, Karagöz, G.Elif

“…The endoplasmic reticulum (ER) regulates essential cellular processes, including protein folding, lipid synthesis, and calcium homeostasis. The ER homeostasis…”
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The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1 by Acosta-Alvear, Diego, Karagöz, G Elif, Fröhlich, Florian, Li, Han, Walther, Tobias C, Walter, Peter

“…The protein folding capacity of the endoplasmic reticulum (ER) is tightly regulated by a network of signaling pathways, known as the unfolded protein response…”
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IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism by Hornegger, Harald, Anisimova, Aleksandra S., Muratovic, Adnan, Bourgeois, Benjamin, Spinetti, Elena, Niedermoser, Isabell, Covino, Roberto, Madl, Tobias, Karagöz, G. Elif

“…The insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) is a conserved RNA-binding protein that regulates RNA stability, localization and…”
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Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy by Picchianti, Lorenzo, Sánchez de Medina Hernández, Víctor, Zhan, Ni, Irwin, Nicholas AT, Groh, Roan, Stephani, Madlen, Hornegger, Harald, Beveridge, Rebecca, Sawa‐Makarska, Justyna, Lendl, Thomas, Grujic, Nenad, Naumann, Christin, Martens, Sascha, Richards, Thomas A, Clausen, Tim, Ramundo, Silvia, Karagöz, G Elif, Dagdas, Yasin

“…UFMylation involves the covalent modification of substrate proteins with UFM1 (Ubiquitin‐fold modifier 1) and is important for maintaining ER homeostasis…”
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Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells by Anisimova, Aleksandra S, Karagöz, G Elif

“…The conserved family of RNA-binding proteins (RBPs), IGF2BPs, plays an essential role in posttranscriptional regulation controlling mRNA stability,…”
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The Vertebrate Mitotic Checkpoint Protein BUBR1 Is an Unusual Pseudokinase by Suijkerbuijk, Saskia J.E., van Dam, Teunis J.P., Karagöz, G. Elif, von Castelmur, Eleonore, Hubner, Nina C., Duarte, Afonso M.S., Vleugel, Mathijs, Perrakis, Anastassis, Rüdiger, Stefan G.D., Snel, Berend, Kops, Geert J.P.L.

“…Chromosomal stability is safeguarded by a mitotic checkpoint, of which BUB1 and Mad3/BUBR1 are core components. These paralogs have similar, but not identical,…”
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Hsp90 structure and function studied by NMR spectroscopy by Didenko, Tatiana, Duarte, Afonso M.S., Karagöz, G. Elif, Rüdiger, Stefan G.D.

“…The molecular chaperone Hsp90 plays a crucial role in folding and maturation of regulatory proteins. Key aspects of Hsp90's molecular mechanism and its…”
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Recent advances in signal integration mechanisms in the unfolded protein response [version 1; peer review: 2 approved] by Elif, Karagöz G, Aragón Tomás, Acosta-Alvear, Diego

“…Since its discovery more than 25 years ago, great progress has been made in our understanding of the unfolded protein response (UPR), a homeostatic mechanism…”
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VULNERABILITY OF ECONOMIC SECTORS TO GEOMAGNETIC STORMS AND MITIGATION STRATEGIES by Demirköz, M. B., Karagöz, G., Kadıoğlu, Y. K., Sözeri, H.

“…Solar storms and CMEs increase the amount of radiation that reaches the Earth and can perturb the magnetic shielding of the Earth. K and Kp indices quantify…”
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N-terminal domain of human Hsp90 triggers binding to the cochaperone p23 by Karagöz, G. Elif, Duarte, Afonso M. S., Ippel, Hans, Uetrecht, Charlotte, Sinnige, Tessa, van Rosmalen, Martijn, Hausmann, Jens, Heck, Albert J. R., Boelens, Rolf, Rüdiger, Stefan G. D., Lindquist, Susan

“…The molecular chaperone Hsp90 is a protein folding machine that is conserved from bacteria to man. Human, cytosolic Hsp90 is dedicated to folding of chiefly…”
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In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay by Karagöz, G Elif, Peschek, Jirka, Walter, Peter, Acosta-Alvear, Diego

“…The kinase/RNase IRE1 is a key effector of the cellular response to endoplasmic reticulum stress. The RNase activity of IRE1 can be measured in cells or in the…”
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