Search Results - "Karagiozov, Stoyan"
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Development of a 99mTc-labeled tetrazine for pretargeted SPECT imaging using an alendronic acid-based bone targeting model
Published in PloS one (16-04-2024)“…Pretargeting, which is the separation of target accumulation and the administration of a secondary imaging agent into two sequential steps, offers the…”
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Role of Oxidative Metabolism in the Effect of Valproic Acid on Markers of Cell Viability, Necrosis, and Oxidative Stress in Sandwich-Cultured Rat Hepatocytes
Published in Toxicological sciences (01-12-2010)“…Valproic acid (VPA) is a drug known for idiosyncratic hepatotoxicity and is associated with oxidative stress. It is metabolized extensively with at least one…”
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Facile microwave synthesis of uniform magnetic nanoparticles with minimal sample processing
Published in Journal of magnetism and magnetic materials (01-01-2017)“…We present a simple and rapid method for the synthesis of small magnetic nanoparticles (diameters in the order of 5–20nm) and narrow size distributions (CV's…”
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Development of a 99mTc-labeled tetrazine for pretargeted SPECT imaging using an alendronic acid-based bone targeting model
Published in PloS one (01-01-2024)“…Pretargeting, which is the separation of target accumulation and the administration of a secondary imaging agent into two sequential steps, offers the…”
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5
Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems
Published in Journal of controlled release (10-01-2020)“…Using lipid-based drug delivery systems (LbDDS) is an efficient strategy to enhance the low oral bioavailability of poorly water-soluble drugs. Here the oral…”
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Development of a Coflowing Device for the Size-Controlled Preparation of Magnetic-Polymeric Microspheres as Embolization Agents in Magnetic Resonance Navigation Technology
Published in ACS biomaterials science & engineering (12-03-2018)“…Droplet microfluidics technology has recently been introduced to generate particles for many biomedical applications that include therapeutic embolizing agents…”
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Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity
Published in Toxicology and applied pharmacology (01-05-2011)“…The present study was conducted in sandwich-cultured rat hepatocytes to investigate the chemical basis of glutathione (GSH) depletion by valproic acid (VPA)…”
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Valproic acid glucuronidation is associated with increases in 15-F 2t-isoprostane in rats
Published in Free radical biology & medicine (01-06-2005)“…Oxidative stress has been associated with valproic acid (VPA) treatment in rats and studies are ongoing to examine the relationship between VPA…”
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Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats
Published in Free radical biology & medicine (01-06-2005)“…Oxidative stress has been associated with valproic acid (VPA) treatment in rats and studies are ongoing to examine the relationship between VPA…”
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10
Practical Stereoselective Synthesis of (2E)- and (2Z)-4-Cycloalkylidenebut-2-enoic Acids
Published in Synthetic communications (31-12-2004)“…Stereoselective synthesis of α,β-unsaturated esters 7 and 8 was achieved through Horner-Wadsworth-Emmons reaction of β,β-disubstituted α,β-unsaturated…”
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