Search Results - "Karademir, Betül"

Redox Regulation and Cancer Therapy by Yalçın, A Süha, Karademir, Betül

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Quercetin-Induced Cell Death in Human Papillary Thyroid Cancer (B-CPAP) Cells by Yalçın, A. Süha, Koçtürk, Semra, Karademir, Betül, Yılmaz, Ayşe Mine, Kasacı, Tolga, Mutlu Altundağ, Ergül, Taga, Yavuz

“…In this study, we have investigated the antiproliferative effect of quercetin on human papillary thyroid cancer cells and determined the apoptotic mechanisms…”
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Basic mechanisms in endoplasmic reticulum stress and relation to cardiovascular diseases by Sozen, Erdi, Karademir, Betul, Ozer, Nesrin Kartal

“…The folding process is an important step in protein synthesis for the functional shape or conformation of the protein. The endoplasmic reticulum (ER) is the…”
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Endoplasmic reticulum stress related molecular mechanisms in nonalcoholic steatohepatitis by Bozaykut, Perinur, Sahin, Ali, Karademir, Betul, Ozer, Nesrin Kartal

“…[Display omitted] •In NASH, lipid metabolism is dysregulated by increase of lipogenesis and free cholesterol and by decrease of VLDL production.•Lipid…”
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Proteasome inhibitors in cancer therapy: Treatment regimen and peripheral neuropathy as a side effect by Kaplan, Gulce Sari, Torcun, Ceyda Corek, Grune, Tilman, Ozer, Nesrin Kartal, Karademir, Betul

“…Proteasomal system plays an important role in protein turnover, which is essential for homeostasis of cells. Besides degradation of oxidized proteins, it is…”
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Production and characterization of bacterial cellulose scaffold and its modification with hyaluronic acid and gelatin for glioblastoma cell culture by Unal, Semra, Arslan, Sema, Yilmaz, Betul Karademir, Oktar, Faik Nuzhet, Sengil, Ahmet Zeki, Gunduz, Oguzhan

“…Three-dimensional (3D) in vitro cell culture models have recently gained increasing interest in predicting the response of anticancer drugs. In this study…”
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The potential use of natural products to negate hepatic, renal and neuronal toxicity induced by cancer therapeutics by Prša, Patrik, Karademir, Betül, Biçim, Gökhan, Mahmoud, Hatem, Dahan, Inbal, Yalçın, A. Süha, Mahajna, Jamal, Milisav, Irina

“…[Display omitted] Different types of chemotherapeutics are used for cancer treatment. These drugs act on several signal pathways, lead to programmed cell…”
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HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts by Karademir, Betül, Bergquist, Jonas, Ozaltin, Esra, Ece, Asli, Kaga, Elif, Sozen, Erdi, Bozaykut, Perinur, Kartal Ozer, Nesrin

“…Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others,…”
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Effect of electric stimulus on human adipose‐derived mesenchymal stem cells cultured in 3D‐printed scaffolds by Bedir, Tuba, Ulag, Songul, Aydogan, Kivanc, Sahin, Ali, Karademir Yilmaz, Betul, Guvenc, Yahya, Bozlar, Michael, Ustundag, Cem Bulent, Gunduz, Oguzhan

“…Electrical stimulation has shown great potential for nerve regeneration processes. This makes it attractive to use electrically active materials in the neural…”
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Propolis-Based Nanofiber Patches to Repair Corneal Microbial Keratitis by Ulag, Songul, Ilhan, Elif, Demirhan, Ramazan, Sahin, Ali, Yilmaz, Betul Karademir, Aksu, Burak, Sengor, Mustafa, Ficai, Denisa, Titu, Aurel Mihail, Ficai, Anton, Gunduz, Oguzhan

“…In this research, polyvinyl-alcohol (PVA)/gelatin (GEL)/propolis (Ps) biocompatible nanofiber patches were fabricated via electrospinning technique. The…”
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Protective effects of different exercise modalities in an Alzheimer’s disease-like model by Özbeyli, Dilek, Sarı, Gülce, Özkan, Naziye, Karademir, Betül, Yüksel, Meral, Çilingir Kaya, Özlem Tuğçe, Kasımay Çakır, Özgür

“…•Aerobic exercise improves anxiety-like behaviour in an Alzheimer’s disease-like model.•Aerobic, resistance and combined exercises protect from oxidative…”
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Polycaprolactone/Gelatin/Hyaluronic Acid Electrospun Scaffolds to Mimic Glioblastoma Extracellular Matrix by Unal, Semra, Arslan, Sema, Yilmaz, Betul Karademir, Oktar, Faik Nuzhet, Ficai, Denisa, Ficai, Anton, Gunduz, Oguzhan

“…Glioblastoma (GBM), one of the most malignant types of human brain tumor, is resistant to conventional treatments and is associated with poor survival. Since…”
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Endoplasmic reticulum stress and proteasomal system in amyotrophic lateral sclerosis by Karademir, Betul, Corek, Ceyda, Ozer, Nesrin Kartal

“…Protein processing including folding, unfolding and degradation is involved in the mechanisms of many diseases. Unfolded protein response and/or endoplasmic…”
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Encapsulation of indocyanine green in poly(lactic acid) nanofibers for using as a nanoprobe in biomedical diagnostics by Ege, Zeynep Ruya, Akan, Aydin, Oktar, Faik Nuzhet, Lin, Chi-Chang, Karademir, Betül, Gunduz, Oguzhan

“…[Display omitted] •Solutions physical properties affect on fiber sizes during Coaxial Electrospinning.•In Coaxial Electrospinning, unstable drugs can be…”
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Proteasome Inhibitors in Cancer Therapy and their Relation to Redox Regulation by Sari, Gulce, Okat, Zehra, Sahin, Ali, Karademir, Betul

“…Redox homeostasis is important for the maintenance of cell survival. Under physiological conditions, redox system works in a balance and involves activation of…”
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Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation by Can, Nisan Denizce, Basturk, Ezgi, Kizilboga, Tugba, Akcay, Izzet Mehmet, Dingiloglu, Baran, Tatli, Ozge, Acar, Sevilay, Ozfiliz Kilbas, Pelin, Elbeyli, Efe, Muratcioglu, Serena, Jannuzzi, Ayse Tarbin, Gursoy, Attila, Keskin, Ozlem, Doganay, Hamdi Levent, Karademir Yilmaz, Betul, Dinler Doganay, Gizem

“…Bag-1 is a multifunctional protein that regulates Hsp70 chaperone activity, apoptosis, and proliferation. The three major Bag-1 isoforms have different…”
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Differential co‐expression network analysis elucidated genes associated with sensitivity to farnesyltransferase inhibitor and prognosis of acute myeloid leukemia by Kelesoglu, Nurdan, Kori, Medi, Yilmaz, Betul Karademir, Duru, Ozlem Ates, Arga, Kazim Yalcin

“…Acute myeloid leukemia (AML) is a heterogeneous disease and the most common form of acute leukemia with a poor prognosis. Due to its complexity, the disease…”
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Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib by Karademir, Betul, Sari, Gulce, Jannuzzi, Ayse Tarbin, Musunuri, Sravani, Wicher, Grzegorz, Grune, Tilman, Mi, Jia, Hacioglu-Bay, Husniye, Forsberg-Nilsson, Karin, Bergquist, Jonas, Jung, Tobias

“…The proteasomal system is responsible for the turnover of damaged proteins. Because of its important functions in oncogenesis, inhibiting the proteasomal…”
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Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction by Jannuzzi, Ayse Tarbin, Yilmaz Goler, Ayse Mine, Bayrak, Nilüfer, Yıldız, Mahmut, Yıldırım, Hatice, Karademir Yilmaz, Betul, Shilkar, Deepak, Venkatesan, Raghusrinivasan Jayaprakash, Jayaprakash, Venkatesan, TuYuN, Amaç Fatih

“…Plastoquinone analogs are privileged structures among the known antiproliferative natural product-based compound families. Exploiting one of these analogs as a…”
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Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib by Jannuzzi, Ayse Tarbin, Arslan, Sema, Yilmaz, Ayse Mine, Sari, Gulce, Beklen, Hande, Méndez, Lucía, Fedorova, Maria, Arga, Kazim Yalcin, Karademir Yilmaz, Betul, Alpertunga, Buket

“…Proteasome inhibitors have great success for their therapeutic potential against hematologic malignancies. First generation proteasome inhibitor bortezomib…”
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