A case of metastasizing ovarian granulosa cell tumour in the myocardium of a bitch

Clinical examinations including X-ray analysis, gross pathological, histopathological and ultrastructural investigations were performed on a case of ovarian granulosa cell tumour in a 5-year-old German boxer bitch. Radiographic examination of the abdomen revealed a round, sharply demarcated formatio...

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Bibliographic Details
Published in:	Acta veterinaria Hungarica (Budapest. 1983) Vol. 44; no. 2; p. 189
Main Authors:	Sabocanec, R, Culjak, K, Vrbanac, L, Potocnjak, D, Stanin, D, Vranesić, D, Karacić, T
Format:	Journal Article
Language:	English
Published:	Hungary 1996
Subjects:	Animals Dog Diseases Dogs Female Granulosa Cell Tumor - pathology Granulosa Cell Tumor - secondary Granulosa Cell Tumor - veterinary Heart Neoplasms - pathology Heart Neoplasms - secondary Heart Neoplasms - veterinary Lymphatic Metastasis Ovarian Neoplasms - pathology Ovarian Neoplasms - veterinary
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Summary:	Clinical examinations including X-ray analysis, gross pathological, histopathological and ultrastructural investigations were performed on a case of ovarian granulosa cell tumour in a 5-year-old German boxer bitch. Radiographic examination of the abdomen revealed a round, sharply demarcated formation about 4-5 cm in size. The tumour of the left ovary was of a malignant granulosa cell type, with numerous metastases 5-20 mm in size, present in the myocardium (left ventricle), lungs (in all lobes) and prescapular lymph node. Ultrastructural characterization of the tumour demonstrated closely packed cells, with rough endoplasmic reticulum, indicating markedly enhanced protein synthesis probably associated with rapid cell proliferation.
ISSN:	0236-6290