Search Results - "Kar, Sidhartha S."

Small-molecule oligonucleotides as smart modality for antiviral therapy: a medicinal chemistry perspective by Kar, Sidhartha S, Dhar, Arghya Kusum, Palei, Narahari N, Bhatt, Shvetank

“…Small-molecule oligonucleotides could be exploited therapeutically to silence the expression of viral infection-causing genes, and a few of them are now in…”
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Design, synthesis, and evaluation of novel diphenyl ether derivatives against drug‐susceptible and drug‐resistant strains of Mycobacterium tuberculosis by Kar, Sidhartha S., Bhat, Varadaraj G., Shenoy, Vishnu P., Bairy, Indira, Shenoy, G. Gautham

“…In our efforts to develop druggable diphenyl ethers as potential antitubercular agents, a series of novel diphenyl ether derivatives (5a–f, 6a–f) were designed…”
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Design, synthesis and evaluation of antitubercular activity of Triclosan analogues by Cinu, Thomas A., Sidhartha, S. Kar, Indira, Bairy, Varadaraj, Bhat G., Vishnu, P. Shenoy, Shenoy, G. Gautham

“…Novel Triclosan mimic diphenyl ether derivatives 4a–k were designed and synthesized with lipophilicity considerably lesser than that of Triclosan. The binding…”
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Elucidation of Structure-activity Relationship of 2-Quinolone Derivatives and Exploration of Their Antitumor Potential Through Bax-induced Apoptotic Pathway by Kumar, Nitesh, Raj, Vasanth P., Jayshree, B. S., Kar, Sidhartha S., Anandam, Arvind, Thomas, Seeja, Jain, Prateek, Rai, Amita, Rao, C. M.

“…3‐Aryl‐2‐quinolone derivates were extensively investigated for their inhibition of farnesyl transferase. Taking this as a cue, we studied the other possible…”
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Development and validation of a HPLC method for quantification of rivastigmine in rat urine and identification of a novel metabolite in urine by LC-MS/MS by Arumugam, Karthik, Chamallamudi, Mallikarjuna Rao, Gilibili, Ravindranath Reddy, Mullangi, Ramesh, Ganesan, Subramanian, Kar, Sidhartha S, Averineni, Ranjithkumar, Shavi, Gopal, Udupa, Nayanabhirama

“…A sensitive, specific and accurate HPLC method for the quantification of rivastigmine (RSM) in rat urine was developed and validated. The method involves the…”
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Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents by Kar, Sidhartha S, Bhat G, Varadaraj, Rao, Praveen Pn, Shenoy, Vishnu P, Bairy, Indira, Shenoy, G Gautham

“…A series of triclosan mimic diphenyl ether derivatives have been synthesized and evaluated for their in vitro antitubercular activity against Mycobacterium…”
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Bioisosteric replacement of dihydropyrazole of 4S-(-)-3-(4-chlorophenyl)-N-methyl-N'-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole by Srivastava, Brijesh Kumar, Soni, Rina, Joharapurkar, Amit, Sairam, Kalapatapu V V M, Patel, Jayendra Z, Goswami, Amitgiri, Shedage, Sandeep A, Kar, Sidhartha S, Salunke, Rahul P, Gugale, Shivaji B, Dhawas, Amol, Kadam, Pravin, Mishra, Bhupendra, Sadhwani, Nisha, Unadkat, Vishal B, Mitra, Prasenjit, Jain, Mukul R, Patel, Pankaj R

“…Design, synthesis and conformational analysis of few imidazole and oxazole as bioisosters of…”
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Monastrol mimic Biginelli dihydropyrimidinone derivatives: synthesis, cytotoxicity screening against HepG2 and HeLa cell lines and molecular modeling study by Soumyanarayanan, Uttara, Bhat, Varadaraj G, Kar, Sidhartha S, Mathew, Jesil A

“…Biginelli dihydropyrimidinone derivatives as structural analogs of monastrol, a known human kinesin Eg5 inhibitor, were synthesized. IC 50 values of the…”
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Bioisosteric replacement of dihydropyrazole of 4 S-(−)-3-(4-chlorophenyl)- N-methyl- N′-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole by Srivastava, Brijesh Kumar, Soni, Rina, Joharapurkar, Amit, Sairam, Kalapatapu V.V.M., Patel, Jayendra Z., Goswami, Amitgiri, Shedage, Sandeep A., Kar, Sidhartha S., Salunke, Rahul P., Gugale, Shivaji B., Dhawas, Amol, Kadam, Pravin, Mishra, Bhupendra, Sadhwani, Nisha, Unadkat, Vishal B., Mitra, Prasenjit, Jain, Mukul R., Patel, Pankaj R.

“…Design, synthesis and conformational analysis of few imidazole and oxazole as bioisosters of 4 S-(−)-3-(4-chlorophenyl)- N-methyl-…”
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Bioisosteric replacement of dihydropyrazole of 4S-(-)-3-(4-chlorophenyl)-N-methyl-N'-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-lH-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole by BRIJESH KUMAR SRIVASTAVA, SONI, Rina, DHAWAS, Amol, KADAM, Pravin, MISHRA, Bhupendra, SADHWANI, Nisha, UNADKAT, Vishal B, MITRA, Prasenjit, JAIN, Mukul R, PATEL, Pankaj R, JOHARAPURKAR, Amit, SAIRAM, Kalapatapu V. V. M, PATEL, Jayendra Z, GOSWAMI, Amitgiri, SHEDAGE, Sandeep A, KAR, Sidhartha S, SALUNKE, Rahul P, GUGALE, Shivaji B

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