Search Results - "Kar, Saptarshi"

Local oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions by Kar, Saptarshi, Kavdia, Mahendra

“…Leukocyte-endothelial cell interactions and leukocyte activation are important factors for vascular diseases including nephropathy, retinopathy and angiopathy…”
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Polysaccharide‐based biomaterials in a journey from 3D to 4D printing by Shokrani, Hanieh, Shokrani, Amirhossein, Seidi, Farzad, Mashayekhi, Mohammad, Kar, Saptarshi, Nedeljkovic, Dragutin, Kuang, Tairong, Saeb, Mohammad Reza, Mozafari, Masoud

“…3D printing is a state‐of‐the‐art technology for the fabrication of biomaterials with myriad applications in translational medicine. After stimuli‐responsive…”
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Impact of SOD in eNOS uncoupling: a two-edged sword between hydrogen peroxide and peroxynitrite by Kar, Saptarshi, Bhandar, Bhagyesh, Kavdia, Mahendra

“…In endothelial cell dysfunction, the uncoupling of eNOS results in higher superoxide (O(2)(•-)) and lower NO production and a reduction in NO availability…”
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A pseudo-three-dimensional model for quantification of oxygen diffusion from preglomerular arteries to renal tissue and renal venous blood by Lee, Chang-Joon, Ngo, Jennifer P, Kar, Saptarshi, Gardiner, Bruce S, Evans, Roger G, Smith, David W

“…To assess the physiological significance of arterial-to-venous (AV) oxygen shunting, we generated a new pseudo-three-dimensional computational model of oxygen…”
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Systems Based Study of the Therapeutic Potential of Small Charged Molecules for the Inhibition of IL-1 Mediated Cartilage Degradation by Kar, Saptarshi, Smith, David W, Gardiner, Bruce S, Grodzinsky, Alan J

“…Inflammatory cytokines are key drivers of cartilage degradation in post-traumatic osteoarthritis. Cartilage degradation mediated by these inflammatory…”
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Facile Synthesis and Characterization of Few-Layer Multifunctional Graphene from Sustainable Precursors by Controlled Pyrolysis, Understanding of the Graphitization Pathway, and Its Potential Application in Polymer Nanocomposites by Roy, Amrita, Kar, Saptarshi, Ghosal, Ranjan, Naskar, Kinsuk, Bhowmick, Anil K

“…The key feature of the present work is the dexterous utilization of an apparently destructive process, pyrolysis, for the synthesis of the most esteemed…”
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Vascular geometry and oxygen diffusion in the vicinity of artery-vein pairs in the kidney by Ngo, Jennifer P, Kar, Saptarshi, Kett, Michelle M, Gardiner, Bruce S, Pearson, James T, Smith, David W, Ludbrook, John, Bertram, John F, Evans, Roger G

“…Renal arterial-to-venous (AV) oxygen shunting limits oxygen delivery to renal tissue. To better understand how oxygen in arterial blood can bypass renal…”
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Computational modeling of neuronal nitric oxide synthase biochemical pathway: A mechanistic analysis of tetrahydrobiopterin and oxidative stress by Allboani, Amnah, Kar, Saptarshi, Kavdia, Mahendra

“…Neuronal cell dysfunction plays an important role in neurodegenerative diseases. Oxidative stress can disrupt the redox balance within neuronal cells and may…”
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Effect of Fly Ash as Filler in Rubber: A Comprehensive Study of the Vulcanisate Properties of Styrene- Butadiene Rubber Compounds by DASGUPTA, Mridul, KAR, Saptarshi, DAS GUPTA, Saikat, MUKHOPADHYAY, Rabindra, BANDYOPADHYAY, Abhijit

“…The effect of fly ash as a filler for an ESBR-based compound was studied in the range 0-80 phr. Characterization of fly ash, as received, revealed the…”
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Endothelial NO and O2− production rates differentially regulate oxidative, nitroxidative, and nitrosative stress in the microcirculation by Kar, Saptarshi, Kavdia, Mahendra

“…Endothelial dysfunction causes an imbalance in endothelial NO and O2− production rates and increased peroxynitrite formation. Peroxynitrite and its…”
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How does ascorbate improve endothelial dysfunction? - A computational analysis by Panday, Sheetal, Kar, Saptarshi, Kavdia, Mahendra

“…Low levels of ascorbate (Asc) are observed in cardiovascular and neurovascular diseases. Asc has therapeutic potential for the treatment of endothelial…”
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Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production by Kar, Saptarshi, Kavdia, Mahendra

“…Endothelial dysfunction is associated with increase in oxidative stress and low NO bioavailability. The endothelial NO synthase (eNOS) uncoupling is considered…”
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Unique graphene‐carbon black hybrid nanofiller by a micromechanical cleavage technique as a reinforcing agent in elastomers: Fundamental and experimental studies by Roy, Amrita, Kar, Saptarshi, Ghosal, Ranjan, Mukhopadhyay, Rabindra, Naskar, Kinsuk, Bhowmick, Anil K.

“…In this work, a synthetic technique was developed which effected delamination of graphite into graphene with simultaneous disaggregation of carbon black…”
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Computational analysis of interactions of oxidative stress and tetrahydrobiopterin reveals instability in eNOS coupling by Joshi, Sheetal, Kar, Saptarshi, Kavdia, Mahendra

“…In cardiovascular and neurovascular diseases, an increase in oxidative stress and endothelial dysfunction has been reported. There is a reduction in…”
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Flourishing an Electrochemical Synthetic Route toward Carbon Black-Intercalated Graphene As a Neoteric Hybrid Nanofiller for Multifunctional Polymer Nanocomposites by Roy, Amrita, Kar, Saptarshi, Ghosal, Ranjan, Naskar, Kinsuk, Bhowmick, Anil K

“…This research work presents a creative and facile process for intercalation of graphite layers with the use of carbon black (CB) spacers, opening up the…”
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Study of reinforcement mechanism and structural elucidation of expanded graphite‐carbon black hybrid filler‐SBR nanocomposites through comprehensive analysis of mechanical properties and small angle X‐ray data by Roy, Amrita, Mondal, Titash, Kar, Saptarshi, Naskar, Kinsuk, Ghosal, Ranjan, Mukhopadhyay, Rabindra, Bhowmick, Anil K.

“…Use of hybrid fillers as a reinforcing agent for polymers is found to be critical step toward developing a high‐performance composite material. However,…”
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Vascular SOD levels is more important than Leukocyte Transmigration and Smooth Muscle Cell Activation on Vascular Pathology by Kar, Saptarshi, Kavdia, Mahendra

“…Abstract only Oxidative and nitrosative stress during leukocyte‐endothelial cell interactions lowers activity levels of superoxide dismutase (SOD), causes…”
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Quantitative Analysis of Tetrahydrobiopterin Synthesis and Oxidation in eNOS Uncoupling by Kar, Saptarshi, Kavdia, Mahendra

“…Abstract only The uncoupling of eNOS shifts the production from nitric oxide (NO) to (O 2 •− ). The lack of availability of eNOS co‐factor tetrahydrobiopterin…”
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A comparative study between conventional chemotherapy and photothermal activated nano-sized targeted drug delivery to solid tumor by Kiani Shahvandi, Mohammad, Souri, Mohammad, Tavasoli, Shaghayegh, Moradi Kashkooli, Farshad, Kar, Saptarshi, Soltani, M.

“…Delivery of chemotherapeutic medicines to solid tumors is critical for optimal therapeutic success and minimal adverse effects. We mathematically developed a…”
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Correction to “Flourishing an Electrochemical Synthetic Route toward Carbon Black-Intercalated Graphene As a Neoteric Hybrid Nanofiller for Multifunctional Polymer Nanocomposites” by Roy, Amrita, Kar, Saptarshi, Ghosal, Ranjan, Naskar, Kinsuk, Bhowmick, Anil K

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