Search Results - "Kapur, Raj"

Histology of the Transition Zone in Hirschsprung Disease by Kapur, Raj P

“…Surgical management of Hirschsprung disease requires resection of the aganglionic bowel and transition zone, a length of ganglionic bowel, immediately proximal…”
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Histopathological, Ultrastructural, and Immunohistochemical Findings in MYH11-Variant Visceral Myopathy by Kapur, Raj P.

“…Background: Pathogenic mutations in the smooth muscle myosin heavy chain gene, MYH11, cause megacystis megacolon intestinal hypoperistalsis syndrome and other…”
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Expression of Calretinin in the Cecal Muscularis Interna: Observation and Hypothetical Relevance to Appendicitis by Kapur, Raj P.

“…Background: The unexpected observation of calretinin immunoreactivity in smooth muscle cells in the muscularis propria of the cecum led to a more detailed…”
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Diagnosis of Hirschsprung Disease by Ambartsumyan, Lusine, Smith, Caitlin, Kapur, Raj P

“…Diagnosis or exclusion of Hirschsprung disease (HSCR) is a frequent exercise in any pediatric hospital. Although HSCR may present at different ages and with…”
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Submucosal nerve diameter of greater than 40 μm is not a valid diagnostic index of transition zone pull-through by Kapur, Raj P.

“…Submucosal nerve hypertrophy is a feature of the transition zone in Hirschsprung disease and has been used as a primary diagnostic feature of transition zone…”
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Surgery, Surgical Pathology, and Postoperative Management of Patients With Hirschsprung Disease by Smith, Caitlin, Ambartsumyan, Lusine, Kapur, Raj P

“…Endorectal pullthrough surgery is integral in the treatment of patients with Hirschsprung disease. Several different surgical procedures exist, which share as…”
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Intestinal Neuronal Dysplasia Type B: An Updated Review of a Problematic Diagnosis by Kapur, Raj P, Reyes-Mugica, Miguel

“…Intestinal neuronal dysplasia type B (IND B) is a controversial histopathologic phenotype that has been associated with intestinal dysmotility, either as an…”
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Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis by Kulkarni, Subhash, Micci, Maria-Adelaide, Leser, Jenna, Shin, Changsik, Tang, Shiue-Cheng, Fu, Ya-Yuan, Liu, Liansheng, Li, Qian, Saha, Monalee, Li, Cuiping, Enikolopov, Grigori, Becker, Laren, Rakhilin, Nikolai, Anderson, Michael, Shen, Xiling, Dong, Xinzhong, Butte, Manish J., Song, Hongjun, Southard-Smith, E. Michelle, Kapur, Raj P., Bogunovic, Milena, Pasricha, Pankaj J.

“…According to current dogma, there is little or no ongoing neurogenesis in the fully developed adult enteric nervous system. This lack of neurogenesis leaves…”
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Postoperative Pullthrough Obstruction in Hirschsprung Disease: Etiologies and Diagnosis by Kapur, Raj P, Smith, Caitlin, Ambartsumyan, Lusine

“…Some patients continue to have obstructive symptoms and/or incontinence after pullthrough surgery for Hirschsprung disease. Incontinence can be due to injury…”
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Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome by Quintana, Albert, Kruse, Shane E., Kapur, Raj P., Sanz, Elisenda, Palmiter, Richard D.

“…To explore the lethal, ataxic phenotype of complex I deficiency in Ndufs4 knockout (KO) mice, we inactivated Ndufs4 selectively in neurons and glia (NesKO…”
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Calretinin-Immunoreactive Mucosal Innervation in Very Short-Segment Hirschsprung Disease: A Potentially Misleading Observation by Kapur, Raj P.

“…Absent calretinin-immunoreactive (CRir) mucosal innervation in aganglionic rectal biopsies is considered a useful diagnostic finding for Hirschsprung disease…”
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A new approach for automation of location-based earthwork scheduling in road construction projects by Shah, Raj Kapur

“…Accurate information of working locations is vital for efficient resource planning, safety of the construction site and monitoring the weekly progress of…”
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Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate by Adams Waldorf, Kristina M, Stencel-Baerenwald, Jennifer E, Kapur, Raj P, Studholme, Colin, Boldenow, Erica, Vornhagen, Jay, Baldessari, Audrey, Dighe, Manjiri K, Thiel, Jeff, Merillat, Sean, Armistead, Blair, Tisoncik-Go, Jennifer, Green, Richard R, Davis, Michael A, Dewey, Elyse C, Fairgrieve, Marian R, Gatenby, J Christopher, Richards, Todd, Garden, Gwenn A, Diamond, Michael S, Juul, Sandra E, Grant, Richard F, Kuller, LaRene, Shaw, Dennis W W, Ogle, Jason, Gough, G Michael, Lee, Wonsok, English, Chris, Hevner, Robert F, Dobyns, William B, Gale, Michael, Rajagopal, Lakshmi

“…New animal models of Zika virus (ZIKV) infection are imperative to accelerating efforts to treat or prevent disease in humans. Adams Waldorf et al . now report…”
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Practical pathology and genetics of Hirschsprung's disease by Kapur, Raj P., MD, PhD

“…Diagnosis and management of Hirschsprung's disease (HSCR) requires understanding of the malformation's anatomic features and multigenic nature. Rectal…”
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Are We Underdiagnosing Hirschsprung Disease? by Kapur, Raj P, Ambartsumyan, Lusine, Smith, Caitlin

“…Hirschsprung disease (HSCR) is conventionally defined as aganglionosis of the distal rectum and a variable length of proximal contiguous bowel with a…”
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ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development by Gacem, Nadjet, Kavo, Anthula, Zerad, Lisa, Richard, Laurence, Mathis, Stephane, Kapur, Raj P., Parisot, Melanie, Amiel, Jeanne, Dufour, Sylvie, de la Grange, Pierre, Pingault, Veronique, Vallat, Jean Michel, Bondurand, Nadege

“…The neural crest gives rise to numerous cell types, dysfunction of which contributes to many disorders. Here, we report that adenosine deaminase acting on RNA…”
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Myelin Protein Zero Immunohistochemistry Is Not a Reliable Marker of Extrinsic Mucosal Innervation in Patients With Hirschsprung Disease by Kapur, Raj P., Tisoncik-Go, Jennifer, Gale, Michael

“…Background Innervation of aganglionic rectum in Hirschsprung disease derives from extrinsic nerves which project from cell bodies located outside the bowel…”
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Rectal suction biopsy versus incisional rectal biopsy in the diagnosis of Hirschsprung disease by Green, Nicole, Smith, Caitlin A., Bradford, Miranda C., Ambartsumyan, Lusine, Kapur, Raj P.

“…Background Hirschsprung disease is one of the most common congenital anomalies that affect colorectal function. Rectal biopsy demonstrating the absence of…”
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Disruption of myelin structure and oligodendrocyte maturation in a macaque model of congenital Zika infection by Tisoncik-Go, Jennifer, Stokes, Caleb, Whitmore, Leanne S., Newhouse, Daniel J., Voss, Kathleen, Gustin, Andrew, Sung, Cheng-Jung, Smith, Elise, Stencel-Baerenwald, Jennifer, Parker, Edward, Snyder, Jessica M., Shaw, Dennis W., Rajagopal, Lakshmi, Kapur, Raj P., Adams Waldorf, Kristina M., Gale, Michael

“…Zika virus (ZikV) infection during pregnancy can cause congenital Zika syndrome (CZS) and neurodevelopmental delay in infants, of which the pathogenesis…”
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Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy by Kruse, Shane E., Watt, William C., Marcinek, David J., Kapur, Raj P., Schenkman, Kenneth A., Palmiter, Richard D.

“…To study effects of mitochondrial complex I (CI, NADH:ubiquinone oxidoreductase) deficiency, we inactivated the Ndufs4 gene, which encodes an 18 kDa subunit of…”
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