Search Results - "Kapur, Arvinder"

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress by Felder, Mildred, Kapur, Arvinder, Gonzalez-Bosquet, Jesus, Horibata, Sachi, Heintz, Joseph, Albrecht, Ralph, Fass, Lucas, Kaur, Justanjyot, Hu, Kevin, Shojaei, Hadi, Whelan, Rebecca J, Patankar, Manish S

“…Over three decades have passed since the first report on the expression of CA125 by ovarian tumors. Since that time our understanding of ovarian cancer biology…”
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Oxidative Phosphorylation: A Target for Novel Therapeutic Strategies Against Ovarian Cancer by Nayak, Amruta P, Kapur, Arvinder, Barroilhet, Lisa, Patankar, Manish S

“…Aerobic glycolysis is an important metabolic adaptation of cancer cells. There is growing evidence that oxidative phosphorylation is also an active metabolic…”
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Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src by Shahzad, Mian M K, Felder, Mildred, Ludwig, Kai, Van Galder, Hannah R, Anderson, Matthew L, Kim, Jong, Cook, Mark E, Kapur, Arvinder K, Patankar, Manish S

“…The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA). MTT assays and QCM™ chemotaxis…”
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Formulation, Characterization, and Antitumor Properties of Trans- and Cis-Citral in the 4T1 Breast Cancer Xenograft Mouse Model by Zeng, San, Kapur, Arvinder, Patankar, Manish S., Xiong, May P.

“…Purpose Citral is composed of a random mixture of two geometric stereoisomers geranial ( trans -citral) and neral ( cis -citral) yet few studies have directly…”
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Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na+/K+-ATPase by Alharbi, Yousef, Kapur, Arvinder, Felder, Mildred, Barroilhet, Lisa, Pattnaik, Bikash R., Patankar, Manish S.

“…Oxidative stress inhibits Na + /K + -ATPase (NKA), the ion channel that maintains membrane potential. Here, we investigate the role of oxidative…”
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The taming of the cell penetrating domain of the HIV Tat: Myths and realities by Chauhan, Ashok, Tikoo, Akshay, Kapur, Arvinder K., Singh, Mahavir

“…Protein transduction with cell penetrating peptides over the past several years has been shown to be an effective way of delivering proteins in vitro and now…”
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M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop by Carroll, Molly J, Kapur, Arvinder, Felder, Mildred, Patankar, Manish S, Kreeger, Pamela K

“…In ovarian cancer, a high ratio of anti-inflammatory M2 to pro-inflammatory M1 macrophages correlates with poor patient prognosis. The mechanisms driving poor…”
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Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes by Belisle, Jennifer A, Horibata, Sachi, Jennifer, Gubbels A A, Petrie, Sarah, Kapur, Arvinder, André, Sabine, Gabius, Hans-Joachim, Rancourt, Claudine, Connor, Joseph, Paulson, James C, Patankar, Manish S

“…MUC16 is a cell surface mucin expressed at high levels by epithelial ovarian tumors. Following proteolytic cleavage, cell surface MUC16 (csMUC16) is shed in…”
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Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells by Alharbi, Yousef, Kapur, Arvinder, Felder, Mildred, Barroilhet, Lisa, Stein, Timothy, Pattnaik, Bikash R., Patankar, Manish S.

“…The Na + /K + -ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of…”
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Data mining of PubChem bioassay records reveals diverse OXPHOS inhibitory chemotypes as potential therapeutic agents against ovarian cancer by Sharma, Sejal, Feng, Liping, Boonpattrawong, Nicha, Kapur, Arvinder, Barroilhet, Lisa, Patankar, Manish S., Ericksen, Spencer S.

“…Focused screening on target-prioritized compound sets can be an efficient alternative to high throughput screening (HTS). For most biomolecular targets,…”
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Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers by Kapur, Arvinder, Mehta, Pooja, Simmons, Aaron D, Ericksen, Spencer S, Mehta, Geeta, Palecek, Sean P, Felder, Mildred, Stenerson, Zach, Nayak, Amruta, Dominguez, Jose Maria Ayuso, Patankar, Manish, Barroilhet, Lisa M

“…Oxidative phosphorylation is an active metabolic pathway in cancer. Atovaquone is an oral medication that inhibits oxidative phosphorylation and is…”
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Terpenoids from Zingiber officinale (Ginger) induce apoptosis in endometrial cancer cells through the activation of p53 by Liu, Yang, Whelan, Rebecca J, Pattnaik, Bikash R, Ludwig, Kai, Subudhi, Enkateswar, Rowland, Helen, Claussen, Nick, Zucker, Noah, Uppal, Shitanshu, Kushner, David M, Felder, Mildred, Patankar, Manish S, Kapur, Arvinder

“…Novel strategies are necessary to improve chemotherapy response in advanced and recurrent endometrial cancer. Here, we demonstrate that terpenoids present in…”
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MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells by Gubbels, Jennifer A A, Felder, Mildred, Horibata, Sachi, Belisle, Jennifer A, Kapur, Arvinder, Holden, Helen, Petrie, Sarah, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S

“…Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on the formation of an immune…”
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The detection, treatment, and biology of epithelial ovarian cancer by Gubbels, Jennifer Aa, Claussen, Nick, Kapur, Arvinder K, Connor, Joseph P, Patankar, Manish S

“…Ovarian cancer is particularly insidious in nature. Its ability to go undetected until late stages coupled with its non-descript signs and symptoms make it the…”
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DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1 by Connor, Joseph P, Felder, Mildred, Kapur, Arvinder, Onujiogu, Nonyem

“…Overcoming platinum resistance is a major obstacle in the treatment of Epithelial Ovarian Cancer (EOC). In our previous work Decoy Receptor 3 (DcR3) was found…”
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Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma by Shahzad, Mian M.K, Shin, Yong-Hyun, Matsuo, Koji, Lu, Chunhua, Nishimura, Masato, Shen, De-Yo, Kang, Yu, Hu, Wei, Mora, Edna M, Rodriguez-Aguayo, Cristian, Kapur, Arvinder, Bottsford-Miller, Justin, Lopez-Berestein, Gabriel, Rajkovic, Aleksandar, Sood, Anil K

“…Highlights ► HORMAD1 is a cancer/testis antigen expressed exclusively in germ cells during normal development. ► HORMAD1 is expressed in a substantial portion…”
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Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface by Gubbels, Jennifer A. A., Gadbaw, Brian, Buhtoiarov, Ilia N., Horibata, Sachi, Kapur, Arvinder K., Patel, Dhara, Hank, Jacquelyn A., Gillies, Stephen D., Sondel, Paul M., Patankar, Manish S., Connor, Joseph

“…The huKS-IL2 immunocytokine (IC) consists of IL2 fused to a mAb against EpCAM, while the hu14.18-IL2 IC recognizes the GD2 disialoganglioside. They are under…”
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Effects of Extracellular ATP on Bovine Lung Endothelial and Epithelial Cell Monolayer Morphologies, Apoptoses, and Permeabilities by McClenahan, David, Hillenbrand, Kati, Kapur, Arvinder, Carlton, David, Czuprynski, Charles

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effects of Lipopolysaccharide and Mannheimia haemolytica Leukotoxin on Bovine Lung Microvascular Endothelial Cells and Alveolar Epithelial Cells by McClenahan, David, Hellenbrand, Katrina, Atapattu, Dhammika, Aulik, Nicole, Carlton, David, Kapur, Arvinder, Czuprynski, Charles

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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High-Throughput Quantitative Glycomics Enabled by 12-plex Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tags by Li, Miyang, Feng, Yu, Ma, Min, Kapur, Arvinder, Patankar, Manish, Li, Lingjun

“…Glycans, which are widely distributed on most proteins and cell surfaces, are a class of important biomolecules playing crucial roles in various biological…”
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