Influenza A virus antigens in children with congenital pathology of central nervous system

The latent circulation of influenza A virus in nursing home children with congenital central nervous abnormality was studied during 1989-1993 by the present-day diagnostic methods for detection of viral antigens. The influenza A virus antigen detection rates correlated with age, genetic predispositi...

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Bibliographic Details
Published in:	Vestnik Rossiĭskoĭ akademii medits︠i︡nskih nauk no. 9; p. 28
Main Authors:	Kaprova, L S, Sominina, A A, Popova, T L, Lipina, N V, Zibina, E A, Grinbaum, E B, Rodionova, V B
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1994
Subjects:	Antigens, Viral - analysis Central Nervous System Diseases - congenital Central Nervous System Diseases - genetics Central Nervous System Diseases - virology Child, Preschool Female Follow-Up Studies Genome, Viral Humans Infant Influenza A virus - genetics Influenza A virus - immunology Influenza A virus - isolation & purification Pregnancy Prenatal Exposure Delayed Effects Time Factors Virus Latency
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Summary:	The latent circulation of influenza A virus in nursing home children with congenital central nervous abnormality was studied during 1989-1993 by the present-day diagnostic methods for detection of viral antigens. The influenza A virus antigen detection rates correlated with age, genetic predisposition, prior acute respiratory diseases in mothers during their pregnancy. There is evidence for long-term (up to 17 months) detection of influenza virus antigens in nasal secretions, as well as for prolonged (up to 7 months) detection of the same genomic sequences of HA gene both in leukocytes and nasal washes.
ISSN:	0869-6047