Search Results - "Kappler, S."

A PNPLA3-Deficient iPSC-Derived Hepatocyte Screen Identifies Pathways to Potentially Reduce Steatosis in Metabolic Dysfunction-Associated Fatty Liver Disease by Doueiry, Caren, Kappler, Christiana S, Martinez-Morant, Carla, Duncan, Stephen A

“…The incidence of nonalcoholic fatty liver disease (NAFLD), or metabolic dysfunction-associated fatty liver disease (MAFLD), is increasing in adults and…”
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Photon-Counting CT of the Brain: In Vivo Human Results and Image-Quality Assessment by Pourmorteza, A, Symons, R, Reich, D S, Bagheri, M, Cork, T E, Kappler, S, Ulzheimer, S, Bluemke, D A

“…Photon-counting detectors offer the potential for improved image quality for brain CT but have not yet been evaluated in vivo. The purpose of this study was to…”
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Relations between Children's and Parents' Behavior in Adoptive Families - A Longitudinal Analysis by Bovenschen, I., Hornfeck, F., Kappler, S.

“…Despite decades of research on adopted children's development, little research has examined the mutual relationship between children's and parents'…”
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KAT6A, a Chromatin Modifier from the 8p11-p12 Amplicon is a Candidate Oncogene in Luminal Breast Cancer by Turner-Ivey, Brittany, Guest, Stephen T, Irish, Jonathan C, Kappler, Christiana S, Garrett-Mayer, Elizabeth, Wilson, Robert C, Ethier, Stephen P

“…Abstract The chromosome 8p11-p12 amplicon is present in 12% to 15% of breast cancers, resulting in an increase in copy number and expression of several…”
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Construction, test and commissioning of the triple-gem tracking detector for compass by Altunbas, C., Capéans, M., Dehmelt, K., Ehlers, J., Friedrich, J., Konorov, I., Gandi, A., Kappler, S., Ketzer, B., De Oliveira, R., Paul, S., Placci, A., Ropelewski, L., Sauli, F., Simon, F., van Stenis, M.

“…The Small Area Tracking system of the COMPASS experiment at CERN includes a set of 20 large area, fast position-sensitive Gas Electron Multiplier detectors,…”
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The effect of tin prefiltration on extremity cone-beam CT imaging with a twin robotic X-ray system by Luetkens, K.S., Huflage, H., Kunz, A.S., Ritschl, L., Herbst, M., Kappler, S., Ergün, S., Goertz, L., Pennig, L., Bley, T.A., Gassenmaier, T., Grunz, J.-P.

“…While tin prefiltration is established in various CT applications, its value in extremity cone-beam CT relative to optimized spectra has not been thoroughly…”
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Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer by Kappler, Christiana S., Guest, Stephen T., Irish, Jonathan C., Garrett-Mayer, Elizabeth, Kratche, Zachary, Wilson, Robert C., Ethier, Stephen P.

“…A subset of triple negative breast cancer (TNBC) is characterized by overexpression of the epidermal growth factor receptor (EGFR) and loss of PTEN, and…”
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Chronic Administration of KB-R7943 Induces Up-regulation of Cardiac NCX1 by Xu, Lin, Kappler, Christiana S., Mani, Santhosh K., Shepherd, Neal R., Renaud, Ludivine, Snider, Paige, Conway, Simon J., Menick, Donald R.

“…The NCX1 (sodium-calcium exchanger) is up-regulated in human heart failure and in many animal models of heart failure. The potential benefits and risks of…”
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Regulation of Ncx1 Gene Expression in the Normal and Hypertrophic Heart by MENICK, DONALD R., RENAUD, LUDIVINE, BUCHHOLZ, AVERY, MÜLLER, JOACHIM G., ZHOU, HONGMING, KAPPLER, CHRISTIANA S., KUBALAK, STEVEN W., CONWAY, SIMON J., XU, LIN

“…:  The Na+/Ca2+ exchanger (NCX1) is crucial in the regulation of [Ca2+]i in the cardiac myocyte. The exchanger is upregulated in cardiac hypertrophy, ischemia,…”
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Interferon lambda receptor-1 isoforms differentially influence gene expression and HBV replication in stem cell-derived hepatocytes by Novotny, Laura A, Evans, J Grayson, Guo, Haitao, Kappler, Christiana S, Meissner, Eric G

“…In the tolerogenic liver, inadequate or ineffective interferon signaling fails to clear chronic HBV infection. Lambda IFNs (IFNL) bind the interferon lambda…”
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Altered chemokine levels in individuals at risk of Type 1 diabetes mellitus by Hanifi-Moghaddam, P., Kappler, S., Seissler, J., Müller-Scholze, S., Martin, S., Roep, B. O., Strassburger, K., Kolb, H., Schloot, N. C.

“…Aims  The hypothesis was tested in an exploratory study that individuals at high risk of developing Type 1 diabetes mellitus have altered systemic levels of…”
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Electron collection and ion feedback in GEM-based detectors by Sauli, F., Kappler, S., Ropelewski, L.

“…We report the results of systematic experimental investigations on electron transmission and ion feedback in a single gas electron multiplier (GEM) detector…”
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Degradation of Iso-α-Acids During Wort Boiling by Kappler, S, Krahl, M, Geissinger, C, Becker, T, Krottenthaler, M

“…A detailed study on the degradation of iso-α-acids was conducted. Because of the complexity of the wort matrix and interfering interactions during real wort…”
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Aging measurements with the Gas Electron Multiplier (GEM) by Altunbas, M.C., Dehmelt, K., Kappler, S., Ketzer, B., Ropelewski, L., Sauli, F., Simon, F.

“…Continuing previous aging measurements with detectors based on the Gas Electron Multiplier (GEM), we investigated a 31×31 cm 2 triple-GEM detector, as used in…”
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High rate X-ray imaging using multi-GEM detectors with a novel readout design by Bachmann, S, Kappler, S, Ketzer, B, Müller, Th, Ropelewski, L, Sauli, F, Schulte, E

“…Modern micropattern gas counters are able to detect soft X-rays with high spatial resolution. Based on the principle of gas amplification, this detector type…”
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49483 Evaluating the Role of IFNLR1 Receptor Dynamics and Plasticity in Regulating Cellular Response to Interferons by Evans, Gray, Kappler, Christiana S., Liu, Ray, Carten, Juliana D., Orr, Cody M., Stephenson, Sarah, Traktman, Paula, Duncan, Stephen A., Meissner, Eric G.

“…ABSTRACT IMPACT: We hope to provide a more nuanced understanding of the type-III IFN system, thereby exploring its therapeutic potential in the realm of…”
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Effect of combined oral proteases and flavonoid treatment in subjects at risk of Type 1 diabetes by Kempf, K., Manzo, G., Hanifi-Moghaddam, P., Kappler, S., Seissler, J., Jaeger, C., Boehm, B., Roden, M., Kolb, H., Martin, S., Schloot, N. C.

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Multibondic cluster algorithm for Monte Carlo simulations of first-order phase transitions by Janke, W, Kappler, S

“…Inspired by the multicanonical approach to simulations of first-order phase transitions we propose for [ital q]-state Potts models a combination of cluster…”
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Discharge studies and prevention in the gas electron multiplier (GEM) by Bachmann, S., Bressan, A., Capeáns, M., Deutel, M., Kappler, S., Ketzer, B., Polouektov, A., Ropelewski, L., Sauli, F., Schulte, E., Shekhtman, L., Sokolov, A.

“…The gas electron multiplier (GEM) used as single proportional counter or in a cascade of two or more elements, permits to attain high gains and to perform…”
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Performance of GEM detectors in high intensity particle beams by Bachmann, S, Bressan, A, Ketzer, B, Deutel, M, Ropelewski, L, Sauli, F, Bondar, A, Buzulutskov, A, Shekhtman, L, Sokolov, A, Tatarinov, A, Vasil'ev, A, Kappler, S, Schulte, E

“…We describe extensive tests of Double Gas Electron Multiplier (GEM) and Triple GEM detectors, including large size prototypes for the COMPASS experiment,…”
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