Search Results - "Kappers, Mariette"

Light-induced vs. bradykinin-induced relaxation of coronary arteries: do S-nitrosothiols act as endothelium-derived hyperpolarizing factors? by BATENBURG, Wendy W, KAPPERS, Mariette H. W, EIKMANN, Melissa J, RAMZAN, Serge N. A, DE VRIES, René, JAN DANSER, A. H

“…Light-induced relaxation depends on S-nitrosothiols. S-Nitrosothiols may also serve as endothelium-derived hyperpolarizing factors, mediating the relaxant…”
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Hypertension Induced by the Tyrosine Kinase Inhibitor Sunitinib Is Associated With Increased Circulating Endothelin-1 Levels by Kappers, Mariëtte H.W, van Esch, Joep H.M, Sluiter, Wim, Sleijfer, Stefan, Danser, A.H. Jan, van den Meiracker, Anton H

“…Angiogenesis inhibition with sunitinib, a multitarget tyrosine kinase inhibitor of the vascular endothelial growth factor receptor, is associated with…”
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Re: Hypertension as a Biomarker of Efficacy in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib by van den Meiracker, Anton H., Danser, A. H. Jan, Sleijfer, Stefan, Kappers, Mariette H. W.

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Treatment of Hypertension and Renal Injury Induced by the Angiogenesis Inhibitor Sunitinib: Preclinical Study by Lankhorst, Stephanie, Kappers, Mariëtte H.W, van Esch, Joep H.M, Smedts, Frank M.M, Sleijfer, Stefan, Mathijssen, Ron H.J, Baelde, Hans J, Danser, A.H Jan, van den Meiracker, Anton H

“…Common adverse effects of angiogenesis inhibition are hypertension and renal injury. To determine the most optimal way to prevent these adverse effects and to…”
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The Vascular Endothelial Growth Factor Receptor Inhibitor Sunitinib Causes a Preeclampsia-Like Syndrome With Activation of the Endothelin System by Kappers, Mariëtte H.W, Smedts, Frank M.M, Horn, Thomas, van Esch, Joep H.M, Sleijfer, Stefan, Leijten, Frank, Wesseling, Sebastiaan, Strevens, Helena, Jan Danser, A.H, van den Meiracker, Anton H

“…Angiogenesis inhibition is an established treatment for several tumor types. Unfortunately, this therapy is associated with adverse effects, including…”
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Sunitinib-Induced Systemic Vasoconstriction in Swine Is Endothelin Mediated and Does Not Involve Nitric Oxide or Oxidative Stress by Kappers, Mariëtte H.W, de Beer, Vincent J, Zhou, Zhichao, Danser, A.H Jan, Sleijfer, Stefan, Duncker, Dirk J, van den Meiracker, Anton H, Merkus, Daphne

“…Angiogenesis inhibition with agents targeting tyrosine kinases of vascular endothelial growth factor receptors is an established anticancer treatment, but is,…”
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Community-acquired necrotizing fasciitis due to Pseudomonas aeruginosa by Kappers, Mariëtte H W, van der Klooster, Johan M, Ouwendijk, Rob J Th, Dees, Ad

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Sunitinib-Induced Hypothyroidism Is due to Induction of Type 3 Deiodinase Activity and Thyroidal Capillary Regression by Kappers, Mariëtte H. W, van Esch, Joep H. M, Smedts, Frank M. M, de Krijger, Ronald R, Eechoute, Karel, Mathijssen, Ron H. J, Sleijfer, Stefan, Leijten, Frank, Danser, A. H. Jan, van den Meiracker, Anton H, Visser, Theo J

“…Context: Anticancer treatment with the tyrosine kinase inhibitor sunitinib causes thyroid dysfunction. Objective: Our objective was to investigate the time…”
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Greater Sensitivity of Blood Pressure Than Renal Toxicity to Tyrosine Kinase Receptor Inhibition With Sunitinib by Lankhorst, Stephanie, Baelde, Hans J, Kappers, Mariëtte H.W, Smedts, Frank M.M, Hansen, Alastair, Clahsen-van Groningen, Marian C, Sleijfer, Stefan, Mathijssen, Ron H.J, Danser, A.H Jan, van den Meiracker, Anton H

“…Hypertension and renal injury are off-target effects of sunitinib, a tyrosine kinase receptor inhibitor used for the treatment of various tumor types…”
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Hypertension during vascular endothelial growth factor inhibition: focus on nitric oxide, endothelin-1, and oxidative stress by Lankhorst, Stephanie, Kappers, Mariëtte H W, van Esch, Joep H M, Danser, A H Jan, van den Meiracker, Anton H

“…Angiogenesis inhibition with humanized antibodies targeting vascular endothelial growth factor (VEGF) or orally active small tyrosine kinase inhibitors…”
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Mechanism of hypertension and proteinuria during angiogenesis inhibition: evolving role of endothelin-1 by Lankhorst, Stephanie, Kappers, Mariëtte H W, van Esch, Joep H M, Danser, A H Jan, van den Meiracker, Anton H

“…Angiogenesis inhibition by blocking vascular endothelial growth factor (VEGF)-mediated signalling with monoclonal antibodies or tyrosine kinase inhibitors has…”
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Cardiovascular and renal toxicity during angiogenesis inhibition: clinical and mechanistic aspects by Kappers, Mariëtte HW, van Esch, Joep HM, Sleijfer, Stefan, Danser, AH Jan, van den Meiracker, Anton H

“…Inhibition of angiogenesis with humanized monoclonal antibodies to vascular endothelial growth factor (VEGF) or with tyrosine kinase inhibitors targeting VEGF…”
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S-52-5: MEASURING DRUG LEVELS USING A DRIED BLOOD SPOT COMBINED WITH PERSONALIZED FEEDBACK TO IMPROVE RESISTANT HYPERTENSION: A RANDOMIZED CONTROLLED TRIAL by Peeters, Laura EJ, Kappers, Mariette HW, Hesselink, Dennis A, Gelder, Teun van, Koch, Birgit CP, Versmissen, Jorie

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Abstract 528: Dose- And Salt-dependency Of Angiogenesis Inhibition-induced Blood Pressure Rise And Renal Toxicity by Lankhorst, Stephanie, Kappers, Mariëtte H, Sleijfer, Stefan, Danser, A H, van den Meiracker, Anton H

“…Abstract only Angiogenesis inhibition with the VEGF inhibitor sunitinib is an established anti-cancer therapy, inducing hypertension and nephrotoxicity. We…”
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Abstract 453: Angiogenesis Inhibition-Induced Hypertension and Nephrotoxicity: Not All Antihypertensives are the Same by Lankhorst, Stephanie, Kappers, Mariëtte H, Van Esch, Joep H, Smedts, Frank M, Sleijfer, Stefan, Danser, Jan A, van den Meiracker, Anton H

“…Abstract only Angiogenesis inhibition with the VEGF inhibitor sunitinib is an established anti-cancer therapy inducing hypertension and nephrotoxicity. Here we…”
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VEGF Inhibition with Sunitinib Results in Endothelin Mediated Hypertension by Beer, Vincent J, Kappers, Mariëtte HW, Verzijl, Annemarie, Danser, AH Jan, Meiracker, Anton H, Duncker, Dirk J, Merkus, Daphne

“…Inhibition of VEGF signaling is an established therapy for various forms of cancer. Unfortunately, this therapy is associated with hypertension and increased…”
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Treatment options for resistant hypertension: from pseudoresistant to refractory hypertension by Versmissen, Jorie, Hendriks, Kelly, van den Meiracker, Anton H, Kappers, Mariëtte H W

“…Resistant hypertension is defined as blood pressure above the target level despite treatment with 3 classes of antihypertensive drugs, including a diuretic. A…”
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New insights into the pathogenesis of pre-eclampsia: the role of angiogenesis-inhibiting factors by Verdonk, Koen, Visser, Willy, Steegers, Eric A P, Kappers, Mariëtte H W, Danser, A H Jan, van den Meiracker, Anton H

“…The pathogenesis of pre-eclampsia is biphasic. The first phase is characterised by insufficient placentation and the second phase by an increased placental…”
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Community-acquired necrotizing fasciitis due to Pseudomonas aeruginosa by Kappers, Mariëtte H W, van der Klooster, Johan M, Ouwendijk, Rob J Th, Dees, Ad

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