Search Results - "Kapoor, Utkarsh"

Unraveling the Structure and Function of Melanin through Synthesis by Cao, Wei, Zhou, Xuhao, McCallum, Naneki C, Hu, Ziying, Ni, Qing Zhe, Kapoor, Utkarsh, Heil, Christian M, Cay, Kristine S, Zand, Tara, Mantanona, Alex J, Jayaraman, Arthi, Dhinojwala, Ali, Deheyn, Dimitri D, Shawkey, Matthew D, Burkart, Michael D, Rinehart, Jeffrey D, Gianneschi, Nathan C

“…Melanin is ubiquitous in living organisms across different biological kingdoms of life, making it an important, natural biomaterial. Its presence in nature…”
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Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’ by Schaefer, Matthias, Kapoor, Utkarsh, Jantsch, Michael F.

“…The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene…”
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A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing by Licht, Konstantin, Kapoor, Utkarsh, Amman, Fabian, Picardi, Ernesto, Martin, David, Bajad, Prajakta, Jantsch, Michael F

“…Pre-mRNA-splicing and adenosine to inosine (A-to-I) RNA-editing occur mostly cotranscriptionally. During A-to-I editing, a genomically encoded adenosine is…”
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Mesoscale Organization and Dynamics in Binary Ionic Liquid Mixtures by Cosby, Tyler, Kapoor, Utkarsh, Shah, Jindal K, Sangoro, Joshua

“…The impact of mesoscale organization on dynamics and ion transport in binary ionic liquid mixtures is investigated by broad-band dielectric spectroscopy,…”
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Preferential Ionic Interactions and Microscopic Structural Changes Drive Nonideality in Binary Ionic Liquid Mixtures as Revealed from Molecular Simulations by Kapoor, Utkarsh, Shah, Jindal K.

“…Thermophysical and structural properties of two binary mixtures of ionic liquids were determined in this study using molecular dynamics simulations at 353 K…”
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TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 by Heinz, Leonhard X., Lee, JangEun, Kapoor, Utkarsh, Kartnig, Felix, Sedlyarov, Vitaly, Papakostas, Konstantinos, César-Razquin, Adrian, Essletzbichler, Patrick, Goldmann, Ulrich, Stefanovic, Adrijana, Bigenzahn, Johannes W., Scorzoni, Stefania, Pizzagalli, Mattia D., Bensimon, Ariel, Müller, André C., King, F. James, Li, Jun, Girardi, Enrico, Mbow, M. Lamine, Whitehurst, Charles E., Rebsamen, Manuele, Superti-Furga, Giulio

“…Toll-like receptors (TLRs) have a crucial role in the recognition of pathogens and initiation of immune responses 1 – 3 . Here we show that a previously…”
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Oculo-renal pathologies- ′Two sides of the same coin by Kapatia, Gargi, Gupta, Gaurav, Kapoor, Utkarsh

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ADAR-deficiency perturbs the global splicing landscape in mouse tissues by Kapoor, Utkarsh, Licht, Konstantin, Amman, Fabian, Jakobi, Tobias, Martin, David, Dieterich, Christoph, Jantsch, Michael F

“…Adenosine-to-inosine RNA editing and pre-mRNA splicing largely occur cotranscriptionally and influence each other. Here, we use mice deficient in either one of…”
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An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype by Bajad, Prajakta, Ebner, Florian, Amman, Fabian, Szabó, Brigitta, Kapoor, Utkarsh, Manjali, Greeshma, Hildebrandt, Alwine, Janisiw, Michael P, Jantsch, Michael F

“…Abstract The RNA-editing protein ADAR is essential for early development in the mouse. Genetic evidence suggests that A to I editing marks endogenous RNAs as…”
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Development of Coarse-Grained Models for Poly(4-vinylphenol) and Poly(2-vinylpyridine): Polymer Chemistries with Hydrogen Bonding by Kapoor, Utkarsh, Kulshreshtha, Arjita, Jayaraman, Arthi

“…In this paper, we identify the modifications needed in a recently developed generic coarse-grained (CG) model that captured directional interactions in…”
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Zooming in on Long Non-Coding RNAs in Ewing Sarcoma Pathogenesis by Aryee, Dave N T, Fock, Valerie, Kapoor, Utkarsh, Radic-Sarikas, Branka, Kovar, Heinrich

“…Ewing sarcoma (ES) is a rare aggressive cancer of bone and soft tissue that is mainly characterized by a reciprocal chromosomal translocation. As a result,…”
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Impact of Polydopamine Nanoparticle Surface Pattern and Roughness on Interactions with Poly(ethylene glycol) in Aqueous Solution: A Multiscale Modeling and Simulation Study by Kapoor, Utkarsh, Jayaraman, Arthi

“…A significant research effort in the past few years has been devoted to engineering synthetic mimics of naturally occurring eumelanin. One such effort has…”
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Self-Assembly of Allomelanin Dimers and the Impact of Poly(ethylene glycol) on the Assembly: A Molecular Dynamics Simulation Study by Kapoor, Utkarsh, Jayaraman, Arthi

“…Synthetic melanin nanoparticles that exhibit properties analogous to naturally found allomelanin can be formed by assembly of dimers/oligomers of the synthetic…”
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Molecular features underlying phase separation of protein-nucleic acid condensates revealed by a new coarse-grained DNA model by Kapoor, Utkarsh, Kim, Youngchan, Mittal, Jeetain

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Monte Carlo Simulations of Pure and Mixed Gas Solubilities of CO 2 and CH 4 in Nonideal Ionic Liquid–Ionic Liquid Mixtures by Kapoor, Utkarsh, Shah, Jindal K.

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Coarse-Grained Models to Study Protein–DNA Interactions and Liquid–Liquid Phase Separation by Kapoor, Utkarsh, Kim, Young C., Mittal, Jeetain

“…Recent advances in coarse-grained (CG) computational models for DNA have enabled molecular-level insights into the behavior of DNA in complex multiscale…”
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Principles Governing the Phase Separation of Multidomain Proteins by Mohanty, Priyesh, Kapoor, Utkarsh, Sundaravadivelu Devarajan, Dinesh, Phan, Tien Minh, Rizuan, Azamat, Mittal, Jeetain

“…A variety of membraneless organelles, often termed “biological condensates”, play an important role in the regulation of cellular processes such as gene…”
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Macroscopic Differentiators for Microscopic Structural Nonideality in Binary Ionic Liquid Mixtures by Kapoor, Utkarsh, Shah, Jindal K

“…Combining two ionic liquids to form a binary ionic liquid mixture is a simple yet effective strategy to not only expand the number of ionic liquids but also…”
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Monte Carlo Simulations of Pure and Mixed Gas Solubilities of CO2 and CH4 in Nonideal Ionic Liquid–Ionic Liquid Mixtures by Kapoor, Utkarsh, Shah, Jindal K

“…The knowledge of mixed gas solubility in ionic liquids at high pressures, which becomes relevant in applications such as tertiary oil recovery and landfill gas…”
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Globular, Sponge-like to Layer-like Morphological Transition in 1‑n‑Alkyl-3-methylimidazolium Octylsulfate Ionic Liquid Homologous Series by Kapoor, Utkarsh, Shah, Jindal K

“…Segregation of polar and nonpolar domains in ionic liquids for which either the cation or anion is responsible for inducing nonpolar domains is well…”
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