Search Results - "Kapoor, Saumya"

Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle by Kapoor, Saumya, Chatterjee, Deep Rohan, Chowdhury, Moumita Ghosh, Das, Rudradip, Shard, Amit

“…Pyruvate kinase M2 (PKM2) has surfaced as a potential target for anti-cancer therapy. PKM2 is known to be overexpressed in the tumor cells and is a critical…”
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Cognitive Skills and DNA Methylation Are Correlating in Healthy and Novice College Students Practicing Preksha Dhyāna Meditation by Abomoelak, Bassam, Prather, Ray, Pragya, Samani U, Pragya, Samani C, Mehta, Neelam D, Uddin, Parvin, Veeramachaneni, Pushya, Mehta, Naina, Young, Amanda, Kapoor, Saumya, Mehta, Devendra

“…The impact of different meditation protocols on human health is explored at the cognitive and cellular levels. Preksha Dhyana meditation has been observed to…”
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ChatGPT-4 Surpasses Residents: A Study of Artificial Intelligence Competency in Plastic Surgery In-service Examinations and Its Advancements from ChatGPT-3.5 by Hubany, Shannon S, Scala, Fernanda D, Hashemi, Kiana, Kapoor, Saumya, Fedorova, Julia R, Vaccaro, Matthew J, Ridout, Rees P, Hedman, Casey C, Kellogg, Brian C, Leto Barone, Angelo A

“…ChatGPT, launched in 2022 and updated to Generative Pre-trained Transformer 4 (GPT-4) in 2023, is a large language model trained on extensive data, including…”
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Speech intelligibility, nasal resonance, and swallowing ability of maxillectomy patients with customized obturator: A non randomized controlled study by Grover, Rohan, Jurel, Sunit, Agarwal, Bhaskar, Rao, Jitendra, Kapoor, Saumya, Mishra, Niraj, Singh, Balendra

“…Aim: To compare speech intelligibility (SI), nasal resonance, and swallowing ability in maxillectomy patients with a customized obturator to the conventional…”
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26. Treatment strategies for few complex situations by Kapoor, Saumya

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Rare diseases and pyruvate kinase M2: a promising therapeutic connection by Kapoor, Saumya, Kalmegh, Vaishnavi, Kumar, Hemant, Mandoli, Amit, Shard, Amit

“…[Display omitted] •Involvement of PKM2 and metabolic reprogramming as a consequence of the Warburg effect has been seen in multiple rare diseases.•PKM2…”
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PROTACting the kinome with covalent warheads by Chatterjee, Deep Rohan, Kapoor, Saumya, Jain, Meenakshi, Das, Rudradip, Chowdhury, Moumita Ghosh, Shard, Amit

“…[Display omitted] •A brief prologue of PROTACs targeting human kinases is focused upon.•Advantages of PROTACs over traditional small molecule drugs.•Role of…”
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Ferrocene-based modulators of cancer-associated tumor pyruvate kinase M2 by Jadhav, Jyotika, Das, Rudradip, Kamble, Sayali, Chowdhury, Moumita Ghosh, Kapoor, Saumya, Gupta, Astha, Vyas, Het, Shard, Amit

“…•Novel and skeletally diverse ferrocene-based triazolopyrimidines were synthesized using a multicomponent reaction.•The compounds exhibited excellent tumor…”
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Half sphere and single clip-bar retained implant supported silicone auricular prosthesis by Kapoor, Saumya, Singh, Saumyendra Vikram, Arya, Deeksha

“…Implant supported auricular prosthesis can be retained by several mechanical means, one of them being the Hader bar and clip system. Conventionally two or more…”
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Evaluation of the Vertical Loop of the Inferior Alveolar Nerve at the Mental Foramen Region - A Retrospective Study by Rajanikanth, B. R., Prasad, Kavitha, Kapoor, Saumya, Choudhary, Aakriti

“…Abstract Introduction: The objective of this study was to assess the vertical loop of the inferior alveolar nerve (IAN) at the mental foramen region by…”
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Technique to prevent fracture of a partial auricular prosthesis mold by Kapoor, Saumya, Singh, Saumyendra V., Arya, Deeksha, Chand, Pooran

“…One of the difficulties faced during the essential and demanding step of fabricating a mold for a partial auricular prosthesis is the fracture of its most…”
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Computational Design, Chemical Synthesis, and Bioevaluation of Pyrimidinyl‐Indoles for Targeting Breast Cancer Cells by Parameswaran, Preethi, Contractor, Darshan, Kalmegh, Vaishnavi, Chaudhary, Bharatkumar, Kapoor, Saumya, Sharma, Satyasheel, Jain, Alok, Shard, Amit

“…Cancer is a global health challenge, despite significant advancements in research. Addressing this issue, we report the design, synthesis and biological…”
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Modulation of tumour pyruvate kinase M2 and suppression of cancer cell proliferation using natural and synthetic antioxidants by Kapoor, Saumya, Kutre, Suraj, Joshi, Swarali, Goswami, Ashutosh, Singh, Amardeep, Teja, Parusu Kavya, Jadhav, Kishori, Tarde, Pooja, Jadhav, Rohini, Raut, Rohit, Solanki, Kajal B., Srivastava, Akshay, Chauthe, Siddheshwar K., Sharma, Satyasheel, Kate, Abhijeet S., Shard, Amit

“…•A total of twenty-four antioxidants were screened using LDH-coupled enzyme assay, in vitro studies, and in silico studies.•Eugenol, a phenylpropanoid, came…”
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Stent for Accurate Placement of Implants for Retaining an Auricular Prosthesis by Kapoor, Saumya, Singh, Saumyendra Vikram, Chowdhury, Adrita Roy, Singh, Arun Kumar

“…Mark the following anatomical landmarks with surgical skin marker pen (Devon Surgical Skin Marker, Regular Tip; Covidien), to form a rectangle which will…”
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Comparison of the effect of different surface treatments on the bond strength of different cements with nickel chromium metal alloy: An in vitro study by Kapoor, Saumya, Prabhu, Nayana, Balakrishnan, Dhanasekar

“…For success of any indirect metal restoration, a strong bond between cement and the intaglio surface of metal is imperative. The aim of this study is to…”
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Prevalence of maxillectomy defects among patients visiting in an institutionalized hospital setting: A prospective, single-institute study by Singh, Mayank, Kapoor, Saumya, Kumar, Lakshya, Pal, U, Singh, Anshulika, Anwar, Mohd

“…Introduction: The rehabilitation of a patient undergone maxillectomy requires a prosthesis that provides with the optimum appearance and functional results…”
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To Study the Effect of Emotional Maturity on Stress and Self Confidence of School Students by Kapoor, Saumya

“…Emotions do play a Central role in the life of an individual. One is expected to have higher emotional maturity in order to lead an effective life. It is also…”
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