Search Results - "Kapoor, Divya"
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Neutrophil Extracellular Traps and Their Possible Implications in Ocular Herpes Infection
Published in Pathogens (Basel) (29-01-2023)“…Neutrophil extracellular traps (NETs) are net-like structures released from neutrophils. NETs predominantly contain cell-free deoxyribonucleic acid (DNA)…”
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Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells
Published in Viruses (30-09-2022)“…Herpes Simplex Virus 1 (HSV-1) is a neurotropic human virus that belongs to the subfamily of . Establishment of its productive infection and progression of…”
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HerpDock: A GUI-based gateway to HSV-1 molecular docking insights
Published in Computational and structural biotechnology journal (01-12-2024)“…Herpes Simplex Virus 1 (HSV-1) is a member of the alpha-Herpesviridae family, with over 60 % of the global population being seropositive. HSV-1 can cause a…”
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Anticoagulation and Antiplatelet Strategies After On-X Mechanical Aortic Valve Replacement
Published in Journal of the American College of Cardiology (19-06-2018)“…The burden oral anticoagulation is a limitation of mechanical valve prostheses. The aim of this study was to test whether patients could be safely managed with…”
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Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication
Published in mBio (26-10-2022)“…Herpes simplex virus type-1 (HSV-1) infections are known to alter the host metabolism for efficient propagation in vitro. However, in vivo metabolic…”
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CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells
Published in Viruses (28-05-2022)“…Herpes simplex virus type-1 (HSV-1) exploits several host factors to enhance its replication and release from infected cells. It induces the production of host…”
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Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress
Published in Viruses (01-09-2021)“…Heparan sulfate (HS) and heparan sulfate proteoglycans (HSPGs) are considered important for the entry of many different viruses. Previously, we demonstrated…”
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Evaluation of mTORC1 signaling in mouse atherosclerotic macrophages by flow cytometry and immunofluorescence
Published in STAR protocols (16-12-2022)“…Previous studies have demonstrated that a high-protein diet leads to increased atherosclerosis in mice, and that this adverse effect is caused by activation of…”
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Diagnostic Accuracy of CT Coronary Angiography
Published in Cardiology clinics (01-11-2009)“…There is a rich and rapidly growing literature on the diagnostic utility of coronary CT angiography (CTA) and its performance relative to other modalities such…”
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Emerging drugs for the treatment of herpetic keratitis
Published in Expert opinion on emerging drugs (01-06-2024)“…Herpes simplex keratitis stands as a prominent factor contributing to infectious blindness among developed nations. On a global scale, over 60% of the…”
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Terminalia arjuna in coronary artery disease: Ethnopharmacology, pre-clinical, clinical & safety evaluation
Published in Journal of ethnopharmacology (11-09-2014)“…Terminalia arjuna (Roxb.) Wight & Arn. is one of the most popular and beneficial medicinal plants in indigenous system of medicine for the treatment of…”
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Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence
Published in Investigative ophthalmology & visual science (01-11-2023)“…PurposeThe objective of this study was to explore the ocular and systemic outcomes of herpes simplex virus type 1 (HSV-1) infection in guinea pigs, to monitor…”
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Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies
Published in Investigative ophthalmology & visual science (11-03-2024)“…Heparanase (HPSE) cleaves heparan sulfate proteoglycans during herpes simplex virus-1 (HSV-1) infection, aiding in viral egress and disease progression. Its…”
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Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection
Published in Investigative ophthalmology & visual science (25-06-2024)“…Neutrophils are known mediators of innate immunity, yet their effector function in herpesvirus infections remains poorly understood. Here, we elucidate the…”
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Virtually All Complications of Active Infective Endocarditis Occurring in a Single Patient
Published in The American journal of cardiology (15-12-2020)“…Described herein is a 49-year-old black man with advanced polycystic renal disease, on hemodialysis for 6 years, who during his last 12 days of life had his…”
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Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection
Published in The Journal of immunology (1950) (01-01-2022)“…Very little knowledge exists on virus-specific host cell intrinsic mechanisms that prevent hyperproliferation of primary HSV type 2 (HSV-2) genital infections…”
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Exploring soil microbiota and their role in plant growth, stress tolerance, disease control and nutrient immobilizer
Published in Biocatalysis and agricultural biotechnology (01-10-2024)“…Agriculture and the human population have historically thrived together; however, the exponential growth of the human population has now surpassed the capacity…”
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Outpatient telecardiology perceptions among rural, suburban, and urban veterans utilizing in‐person cardiology versus telecardiology services: A mixed methods analysis
Published in The Journal of rural health (01-09-2021)“…Purpose To better understand opportunities and barriers to implementation and adoption, this mixed‐methods study qualitatively examined attitudes toward…”
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Abstract P147: Dietary Protein Elicits A Leucine-mediated Threshold Effect On Monocyte/macrophage Mtorc1-autophagy Signaling Resulting In Elevated Cardiovascular Risk
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2021)“…Abstract only High-protein intake is common in Western societies and generally considered healthy. However, results from some epidemiological studies suggest…”
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