Search Results - "Kaplan, Joshua P."

Structures of the otopetrin proton channels Otop1 and Otop3 by Saotome, Kei, Teng, Bochuan, Tsui, Che Chun (Alex), Lee, Wen-Hsin, Tu, Yu-Hsiang, Kaplan, Joshua P., Sansom, Mark S. P., Liman, Emily R., Ward, Andrew B.

“…Otopetrins (Otop1–Otop3) comprise one of two known eukaryotic proton-selective channel families. Otop1 is required for otoconia formation and a candidate…”
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Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus by Teng, Bochuan, Kaplan, Joshua P, Liang, Ziyu, Chyung, Kevin Saejin, Goldschen-Ohm, Marcel P, Liman, Emily R

“…Otopetrin proteins (OTOPs) form proton-selective ion channels that are expressed in diverse cell types where they mediate detection of acids or regulation of…”
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Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels by Teng, Bochuan, Kaplan, Joshua P, Liang, Ziyu, Krieger, Zachary, Tu, Yu-Hsiang, Burendei, Batuujin, Ward, Andrew B, Liman, Emily R

“…Otopetrin (OTOP) channels are proton-selective ion channels conserved among vertebrates and invertebrates, with no structural similarity to other ion channels…”
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Generalizable Compositional Features Influencing the Proteostatic Fates of Polar Low-Complexity Domains by Cascarina, Sean M., Kaplan, Joshua P., Elder, Mikaela R., Brookbank, Lindsey, Ross, Eric D.

“…Protein aggregation is associated with a growing list of human diseases. A substantial fraction of proteins in eukaryotic proteomes constitutes a proteostasis…”
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Subtype-specific potentiation of otopetrin proton channels by Zn2+ and its structural basis by Kaplan, Joshua P., Teng, Bochuan, Goldschen-Ohm, Marcel P., Liman, Emily R.

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Subtype-specific potentiation of otopetrin proton channels by Zn 2+ and its structural basis by Kaplan, Joshua P, Teng, Bochuan, Goldschen-Ohm, Marcel P, Liman, Emily R

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